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INHBB / Inhibin Beta B

inhibin, beta B

The inhibin beta B subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumour-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. Because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Furthermore, the beta B subunit forms a homodimer, activin B, and also joins with the beta A subunit to form a heterodimer, activin AB, both of which stimulate FSH secretion.

Gene Name: inhibin, beta B
Family/Subfamily: TGF beta , not assigned-TGF beta
Synonyms: INHBB, Activin beta-B chain, Activin AB beta polypeptide, Inhibin, beta B, Inhibin Beta B, Inhibin beta B chain, Inhibin, beta-2
Target Sequences: NM_002193 NP_002184.2 P09529

Publications (1)

1
Inhibin B in seminiferous tubules of human testes in normal spermatogenesis and in idiopathic infertility. Grigory A Demyashkin. Systems biology in reproductive medicine. 2019 Feb;65:20-28. [Full Text Article] [PubMed:29886763]

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Antibodies (99)
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INHBB / Inhibin Beta B (99)
Human (54)
Mouse (33)
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rabbit (81)
mouse (18)
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aa293-407 (17)
aa277-391 (16)
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No (99)
INHBB / Inhibin Beta B Antibody - Human Heart: Formalin-Fixed, Paraffin-Embedded (FFPE)
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INHBB / Inhibin Beta B Rabbit anti-Human Polyclonal (Internal) Antibody
Chicken, Zebrafish, Pig, Mouse, Rat, Sheep, Bovine, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
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INHBB / Inhibin Beta B Mouse anti-Human Monoclonal (aa293-407) Antibody
Human
ELISA, Neut, WB
Unconjugated
100 µg/$751
INHBB / Inhibin Beta B Antibody - INHBB Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human liver tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
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INHBB / Inhibin Beta B Rabbit anti-Human Polyclonal (aa369-397) Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
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INHBB / Inhibin Beta B Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Chicken, Rat, Pig, Mouse, Human
ELISA, WB
Unconjugated
0.1 mg/$379
INHBB / Inhibin Beta B Antibody - Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE)
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INHBB / Inhibin Beta B Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
INHBB / Inhibin Beta B Antibody - Immunohistochemistry of Inhibin beta-B antibody
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INHBB / Inhibin Beta B Rabbit anti-Human Polyclonal (351-400 aa, C-terminal) Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
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INHBB / Inhibin Beta B Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC
Unconjugated
100 µg/$331
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INHBB / Inhibin Beta B Mouse anti-Human Monoclonal (1.A.22) Antibody
Human
ELISA
Unconjugated
100 µg/$842
INHBB / Inhibin Beta B Antibody - Western Blot; Sample: Recombinant INHbB, Human.
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INHBB / Inhibin Beta B Mouse anti-Human Monoclonal Antibody
Human
WB
Unconjugated
100 µl/$309; 200 µl/$351; 500 µl/$492; 1 ml/$563; 2 ml/$758; 5 ml/$1,233
INHBB / Inhibin Beta B Antibody - Western blot of recombinant Inhibin Beta B / INHBB.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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INHBB / Inhibin Beta B Rabbit anti-Human Polyclonal (aa293-407) Antibody
Human
WB
Unconjugated
100 µl/$303; 200 µl/$343; 500 µl/$476; 1 ml/$543; 2 ml/$715; 5 ml/$1,182
INHBB / Inhibin Beta B Antibody - Western blot of recombinant Inhibin Beta B / INHBB.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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INHBB / Inhibin Beta B Rabbit anti-Human Polyclonal (aa293-407) (Biotin) Antibody
Human
WB
Biotin Conjugated
100 µl/$313; 200 µl/$357; 500 µl/$503; 1 ml/$576; 2 ml/$788; 5 ml/$1,279
INHBB / Inhibin Beta B Antibody - : Formalin-Fixed, Paraffin-Embedded (FFPE), Testis, at a concentration of 5 ug/ml.
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INHBB / Inhibin Beta B Rabbit anti-Human Polyclonal (aa369-397) Antibody
Mouse, Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$485
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INHBB / Inhibin Beta B Rabbit anti-Mouse Polyclonal (aa369-397) (HRP) Antibody
Mouse
ELISA, IHC, WB
HRP Conjugated
200 µl/$952
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INHBB / Inhibin Beta B Rabbit anti-Mouse Polyclonal (aa369-397) (Biotin) Antibody
Mouse
ELISA, IHC, WB
Biotin Conjugated
200 µl/$952
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INHBB / Inhibin Beta B Rabbit anti-Mouse Polyclonal (aa369-397) (FITC) Antibody
Mouse
IHC, WB
FITC Conjugated
200 µl/$952
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INHBB / Inhibin Beta B Rabbit anti-Mouse Polyclonal (aa369-397) (PE) Antibody
Mouse
ELISA, IHC, WB
PE Conjugated
200 µl/$952
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INHBB / Inhibin Beta B Rabbit anti-Mouse Polyclonal (aa369-397) (APC) Antibody
Mouse
ELISA, IHC, WB
APC Conjugated
200 µl/$952
INHBB / Inhibin Beta B Antibody - Immunochemical staining of human Inhibin beta B in human liver with rabbit polyclonal antibody at 1:200 dilution, formalin-fixed paraffin embedded sections.
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INHBB / Inhibin Beta B Rabbit anti-Human Polyclonal (Preservative Free) Antibody
Human
ICC, IF, IHC-P
Unconjugated, Preservative Free
100 µl/$412
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INHBB / Inhibin Beta B Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
INHBB / Inhibin Beta B Antibody - Immunohistochemistry of paraffin-embedded human kidney tissue using INHBB Antibody at dilution of 1:100
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INHBB / Inhibin Beta B Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
50 µg/$294; 100 µg/$360
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INHBB / Inhibin Beta B Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA, WB
HRP Conjugated
50 µg/$294; 100 µg/$360
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INHBB / Inhibin Beta B Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
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INHBB / Inhibin Beta B Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
20 µg/$242; 100 µg/$304; 200 µg/$334; 500 µg/$452
INHBB / Inhibin Beta B Antibody - Western blot analysis of lysate from HeLa cells, using Inhibin β-B antibody.
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INHBB / Inhibin Beta B Rabbit anti-Human Polyclonal (aa75-124) Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
INHBB / Inhibin Beta B Antibody - Western blot analysis of Inhibin BetaB expression in HeLa cells
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INHBB / Inhibin Beta B Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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