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2 Shaker Rd Suites
B001/B101
Shirley, MA 01464
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Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036
Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors.
Gene Name: | IMP (inosine 5'-monophosphate) dehydrogenase 1 |
Synonyms: | IMPDH1, IMP dehydrogenase 1, IMPD 1, IMPDH 1, IMPD1, LCA11, IMPD, IMPDH-I, SWSS2608, RP10 |
Target Sequences: | NM_000883 NP_000874.2 P20839 |
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