IMPACT

impact RWD domain protein

Translational regulator that ensures constant high levels of translation under amino acid starvation. Acts by interacting with GCN1/GCN1L1, thereby preventing activation of GCN2 protein kinases (EIF2AK1 to 4) and subsequent down-regulation of protein synthesis By similarity. May be required to regulate translation in specific neuronal cells under amino acid starvation conditions by preventing GCN2 activation and therefore ATF4 synthesis By similarity. Through its action on GCN2, may also facilitate neuritogenesis.

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Products

Proteins (5)

Type

Over-Expression Lysate (2)

Recombinant (3)

Target

IMPACT (5)

Publications

No (5)

Tag

GST (1)

His (1)

Myc-DDK (Flag) (3)

Species

Human (4)

Source

293T Cells (1)

E. coli (1)

HEK 293 Cells (2)

Wheat Germ Extract (1)

Purification

Purified (2)

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Human IMPACT Protein (Recombinant His) - LS-G2482

Source:

E. coli

Tag:

His

Price:

100 µg/$361; 500 µg/$739; 20 µg/$261

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Human IMPACT Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G69278

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

36.3 kDa

Price:

20 µg/$1,107

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Human IMPACT Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G84249

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

36.3 kDa

Price:

20 µg/$150

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Human IMPACT Protein (Recombinant GST) (Full Length) - LS-G34305

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

60.83 kDa

Price:

10 µg/$479; 25 µg/$670

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IMPACT Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G111672

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

36.3 kDa

Price:

100 µg/$494

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