IMPA1 / IMP

inositol(myo)-1(or 4)-monophosphatase 1

IMPA1 / IMP is an enzyme that dephosphorylates myo-inositol monophosphate to generate free myo-inositol, a precursor of phosphatidylinositol, and is therefore an important modulator of intracellular signal transduction via the production of the second messengers myoinositol 1,4,5-trisphosphate and diacylglycerol. This enzyme can also use myo-inositol-1,3-diphosphate, myo-inositol-1,4-diphosphate, scyllo-inositol-phosphate, glucose-1-phosphate, glucose-6-phosphate, fructose-1-phosphate, beta-glycerophosphate, and 2'-AMP as substrates. This enzyme shows magnesium-dependent phosphatase activity and is inhibited by therapeutic concentrations of lithium. Inhibition of inositol monophosphate hydroylosis and subsequent depletion of inositol for phosphatidylinositol synthesis may explain the anti-manic and anti-depressive effects of lithium administered to treat bipolar disorder. Alternative splicing results in multiple transcript variants encoding distinct isoforms. A pseudogene of this gene is also present on chromosome 8q21.13.

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Antibodies (19)

Proteins (11)

ELISA Kits (6)

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Custom (4)

Over-Expression Lysate (4)

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Recombinant (7)

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Target

IMPA1 / IMP (36)

Reactivity

Human (21)

Mouse (15)

Rat (8)

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Monkey (3)

Orangutan (3)

Pig (1)

Rabbit (3)

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rabbit (17)

mouse (2)

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IgG (13)

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monoclonal mc (2)

polyclonal pc (17)

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Format

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IMPA1 / IMP Antibody LS-C666437

Antibody:

IMPA1 / IMP Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, WB

Format:

Unconjugated

Price:

100 µg/$331

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IMPA1 / IMP Antibody LS-C334674

Antibody:

IMPA1 / IMP Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 100 µl/$389

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IMPA1 / IMP Antibody (clone AT2G5) LS-C755491

Antibody:

IMPA1 / IMP Mouse anti-Human Monoclonal (AT2G5) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, ICC, WB

Format:

Unconjugated

Price:

50 µl/$303; 100 µl/$365

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Mouse IMPA1 / IMP (Sandwich ELISA) ELISA Kit - LS-F17125

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

78 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$669

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IMPA1 / IMP Antibody LS-C767557

Antibody:

IMPA1 / IMP Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC, WB

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

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IMPA1 / IMP Antibody LS-C830482

Antibody:

IMPA1 / IMP Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

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IMPA1 / IMP Antibody (clone 1E6-F11) LS-C197531

Antibody:

IMPA1 / IMP Mouse anti-Human Monoclonal (1E6-F11) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µg/$423

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IMPA1 / IMP Antibody LS-C831984

Antibody:

IMPA1 / IMP Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

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IMPA1 / IMP Antibody (aa227-277) LS-C762942

Antibody:

IMPA1 / IMP Rabbit anti-Human Polyclonal (aa227-277) Antibody

Reactivity:

Mouse, Human

Applications:

IP, WB

Format:

Unconjugated

Price:

10 µl/$295; 100 µl/$514

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IMPA1 / IMP Antibody LS-C311280

Antibody:

IMPA1 / IMP Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Unconjugated

Price:

100 µg/$749

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IMPA1 / IMP Antibody (HRP) LS-C542727

Antibody:

IMPA1 / IMP Rabbit anti-Human Polyclonal (HRP) Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$937

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IMPA1 / IMP Antibody (Biotin) LS-C522594

Antibody:

IMPA1 / IMP Rabbit anti-Human Polyclonal (Biotin) Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$937

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IMPA1 / IMP Antibody (FITC) LS-C532639

Antibody:

IMPA1 / IMP Rabbit anti-Human Polyclonal (FITC) Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$937

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IMPA1 / IMP Antibody (APC) LS-C514380

Antibody:

IMPA1 / IMP Rabbit anti-Human Polyclonal (APC) Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

APC Conjugated

Price:

100 µl/$937

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IMPA1 / IMP Antibody (PE) LS-C650840

Antibody:

IMPA1 / IMP Rabbit anti-Human Polyclonal (PE) Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

PE Conjugated

Price:

100 µl/$937

• Unconjugated
• HRP
• Biotin
• FITC
• APC
• PE

• Unconjugated
• HRP
• Biotin
• More...
  • FITC
  • APC
  • PE

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IMPA1 / IMP Antibody (C-Terminus) LS-C112233

Antibody:

IMPA1 / IMP Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

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IMPA1 / IMP Antibody (C-Terminus, HRP) LS-C465074

Antibody:

IMPA1 / IMP Rabbit anti-Human Polyclonal (C-Terminus) (HRP) Antibody

Reactivity:

Rabbit, Mouse, Guinea pig, Rat, Orangutan, Human, Monkey

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$469

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IMPA1 / IMP Antibody (C-Terminus, Biotin) LS-C465072

Antibody:

IMPA1 / IMP Rabbit anti-Human Polyclonal (C-Terminus) (Biotin) Antibody

Reactivity:

Rabbit, Mouse, Guinea pig, Rat, Orangutan, Human, Monkey

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$469

Select

IMPA1 / IMP Antibody (C-Terminus, FITC) LS-C465073

Antibody:

IMPA1 / IMP Rabbit anti-Human Polyclonal (C-Terminus) (FITC) Antibody

Reactivity:

Rabbit, Mouse, Guinea pig, Rat, Orangutan, Human, Monkey

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

IMPA1 / IMP Antibody (aa25-75) LS-C762946

Antibody:

IMPA1 / IMP Rabbit anti-Human Polyclonal (aa25-75) Antibody

Reactivity:

Human

Applications:

IP

Format:

Unconjugated

Price:

10 µg/$295; 100 µl/$514

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Human IMPA1 / IMP Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G66342

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

30 kDa

Price:

20 µg/$1,107

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Bovine IMPA1 / IMP (Custom ELISA) ELISA Kit - LS-F17124

Type:

Custom

Format:

96-Well Strip Plate

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$669

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Pig IMPA1 / IMP (Custom ELISA) ELISA Kit - LS-F17126

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Pig

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$669

Select

Human IMPA1 / IMP (Custom ELISA) ELISA Kit - LS-F17127

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

31.2 - 2000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$669

Select

Rat IMPA1 / IMP (Custom ELISA) ELISA Kit - LS-F17128

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Rat

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$669

Viewing 1-25 of 36 product results

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