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ILT3 / LILRB4

leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4

ILT3 / LILRB4 is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. The receptor can also function in antigen capture and presentation. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene Name: leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4
Family/Subfamily: Immunoglobulin , not assigned-Immunoglobulin
Synonyms: LILRB4, CD85K, CD85k antigen, ILT-3, ILT3, LIR-5, LIR5, HM18
Target Sequences: NM_006847 NP_006838.3 Q8NHJ6

Publications (1)

1
NCR(+)ILC3 concentrate in human lung cancer and associate with intratumoral lymphoid structures. Carrega P, Loiacono F, Di Carlo E, Scaramuccia A, Mora M, Conte R, Benelli R, Spaggiari GM, Cantoni C, Campana S, Bonaccorsi I, Morandi B, Truini M, Mingari MC, Moretta L, Ferlazzo G. Nature communications. 2015 6:8280. (WB; Human) [Full Text Article] [PubMed:26395069] Related Antibodies: LS-C261904.

☰ Filters
Products
Proteins (12)
Over-Expression Lysate (4)
Recombinant (8)
ILT3 / LILRB4 (12)
No (12)
Fc, C-terminus (3)
GST (1)
His, C-Terminal (1)
His,C-terminus (2)
His-T7 (1)
Myc-DDK (Flag) (4)
Human (6)
Mouse (4)
293T Cells (2)
E. coli (1)
HEK 293 Cells (3)
Human (2)
Mammalian Cells (3)
Wheat Germ Extract (1)
Purified (2)
Low endotoxin level (6)
ILT3 / LILRB4 Protein - Recombinant Leukocyte Immunoglobulin Like Receptor Subfamily B, Member 4 By SDS-PAGE
Select
E. coli
His-T7
24.3 kDa
10 µg/$289; 50 µg/$492; 100 µg/$785; 200 µg/$982; 1 mg/$2,119; 500 µg/$1,646; 5 mg/$3,431; 2 mg/$2,309
ILT3 / LILRB4 Protein - 12.5% SDS-PAGE of human LILRB4 stained with Coomassie Blue
Select
Wheat Germ Extract
GST
75.02 kDa
10 µg/$479; 25 µg/$670
ILT3 / LILRB4 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
49 kDa
20 µg/$215
ILT3 / LILRB4 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
49.2 kDa
20 µg/$150
ILT3 / LILRB4 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
49 kDa
100 µg/$710
ILT3 / LILRB4 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
49.2 kDa
100 µg/$494
ILT3 / LILRB4 Protein - Recombinant Mouse Leukocyte Ig-Like Receptor B4/LILRB4/CD85k/ILT3 (C-Fc)
Select
Human
Fc, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
51 kDa
10 µg/$308; 50 µg/$502
Select
Human
His, C-Terminal
Less than 1.0 EU/µg protein (determined by LAL method).
24.9kD
10 µg/$288; 50 µg/$442; 500 µg/$1,377; 1 mg/$1,765
Select
HEK 293 Cells
Fc, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
52.8 kDa
100 µg/$1,070; 1 mg/$7,069
Select
Mammalian Cells
His,C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
24.9 kDa
10 µg/$288; 50 µg/$436
Select
Mammalian Cells
Fc, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
53.2 kDa
10 µg/$317; 50 µg/$524
Select
Mammalian Cells
His,C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
27.1 kDa
10 µg/$317; 50 µg/$524
Viewing 1-12 of 12 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).