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ILT3 / LILRB4

leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4

ILT3 / LILRB4 is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. The receptor can also function in antigen capture and presentation. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene Name: leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4
Family/Subfamily: Immunoglobulin , not assigned-Immunoglobulin
Synonyms: LILRB4, CD85K, CD85k antigen, ILT-3, ILT3, LIR-5, LIR5, HM18
Target Sequences: NM_006847 NP_006838.3 Q8NHJ6

Publications (1)

1
NCR(+)ILC3 concentrate in human lung cancer and associate with intratumoral lymphoid structures. Carrega P, Loiacono F, Di Carlo E, Scaramuccia A, Mora M, Conte R, Benelli R, Spaggiari GM, Cantoni C, Campana S, Bonaccorsi I, Morandi B, Truini M, Mingari MC, Moretta L, Ferlazzo G. Nature communications. 2015 6:8280. (WB; Human) [Full Text Article] [PubMed:26395069] Related Antibodies: LS-C261904.

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ELISA Kits (12)
Sandwich (11)
Sandwich CLIA (1)
ILT3 / LILRB4 (12)
Human (6)
Mouse (1)
Chicken (1)
Guinea pig (1)
Monkey (1)
Porcine (1)
Rabbit (1)
12 x 8-Well Microstrips (1)
96-Well Microplate (2)
96-Well Strip Plate (9)
No (12)
Cell Culture Supernatants (1)
Plasma (6)
Serum (6)
Tissue Homogenates (2)
ILT3 / LILRB4 ELISA Kit
Select
Sandwich
96-Well Microplate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$586
ILT3 / LILRB4 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
ILT3 / LILRB4 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
ILT3 / LILRB4 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Tissue Homogenates
1 Plate/$798
ILT3 / LILRB4 ELISA Kit
Select
Sandwich CLIA
12 x 8-Well Microstrips
Human
31.25 - 2000 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$656
ILT3 / LILRB4 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
ILT3 / LILRB4 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Chicken
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
ILT3 / LILRB4 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Guinea pig
125 - 8000 pg/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
ILT3 / LILRB4 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Monkey
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
ILT3 / LILRB4 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Porcine
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
ILT3 / LILRB4 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rabbit
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
ILT3 / LILRB4 ELISA Kit
Select
Sandwich
96-Well Microplate
Human
1.3 - 300 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$610
Viewing 1-12 of 12 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).