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Corporate Headquarters
Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
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Customer Service: (800) 227-6666 / (650) 697-3600
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IL8 / Interleukin 8
interleukin 8
Interleukin 8 (IL8), a member of the CXC chemokine family. This chemokine, is one of the major mediators of the inflammatory response. This chemokine is secreted by several cell types. It functions as a chemoattractant, and is also a potent angiogenic factor. This gene is believed to play a role in the pathogenesis of bronchiolitis, a common respiratory tract disease caused by viral infection. This gene and other ten members of the CXC chemokine gene family form a chemokine gene cluster in a region mapped to chromosome 4q.
| Gene Name: | interleukin 8 |
| Family/Subfamily: | Intercrine , Intercrine alpha |
| Synonyms: | CXCL8, 3-10C, AMCF-I, B-ENAP, C-X-C motif chemokine 8, GCP-1, IL-8, IL8, Interleukin-8, K60, LECT, GCP1, LUCT, NAF, NAP1, Neutrophil-activating factor, Interleukin 8, Protein 3-10C, MDNCF, TSG-1, Emoctakin, LYNAP, MONAP, NAP-1, SCYB8, T-cell chemotactic factor |
| Target Sequences: | NM_000584 NP_000575.1 P10145 |
Publications (6)
1
Unique early gene expression patterns in human adult-to-adult living donor liver grafts compared to deceased donor grafts. de Jonge J, Kurian S, Shaked A, Reddy KR, Hancock W, Salomon DR, Olthoff KM. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 2009 9:758-72. (IHC)
[PubMed:19353763]
[PMC:PMC2734955]
2
Autocrine IL-8 promotes F-actin polymerization and mediate mesenchymal transition via ELMO1-NF-?B-Snail signaling in glioma. Zhang B, Shi L, Lu S, Sun X, Liu Y, Li H, Wang X, Zhao C, Zhang H, Wang Y. Cancer biology & therapy. 2015 16:898-911. (IHC, WB; Human)
[Full Text Article]
[PubMed:25870011]
[PMC:PMC4623112]
Related Antibodies: LS-C104558.
3
Expression and secretion of the pro-inflammatory cytokine IL-8 is increased in colorectal cancer cells following the knockdown of non-erythroid spectrin aII. Anne Ackermann, Barbara Lafferton, Guido Plotz, Stefan Zeuzem, Angela Brieger. International journal of oncology. 2020 June;56:1551-1564. [Full Text Article]
[PubMed:32236629]
Related Antibodies: LS-C663556.
☰ Filters
Products
Proteins
(57)
Type
Over-Expression Lysate
(2)
Recombinant
(53)
Target
IL8 / Interleukin 8
(57)
Product Group
Coronavirus Antibodies Proteins cDNAs
(57)
Cytokine Release Syndrome
(57)
Cytokine Release Syndrome Proteins
(57)
Format
Animal-free
(1)
Publications
No
(57)
Tag
6His, C-terminus
(3)
6His, N-terminus
(3)
Fc
(2)
GST
(2)
GST, N-terminus
(1)
His
(11)
His, N-Terminal
(1)
His-S
(2)
His-T7
(3)
Human Mutant IgG1 Fc
(1)
Myc-DDK (Flag)
(3)
Species
Chicken
(3)
Cow
(1)
Dog
(4)
Guinea pig
(1)
Horse
(1)
Human
(37)
Pig
(3)
Rabbit
(2)
Rhesus monkey
(2)
Sheep
(2)
Source
293F Cells
(1)
293T Cells
(1)
CHO Cells
(2)
E. coli
(36)
HEK 293 Cells
(2)
Human Cells
(5)
Mammalian Cells
(3)
Wheat Germ Extract
(2)
Yeast
(4)
Purification
Purified
(21)
Low Endotoxin Level
Low endotoxin level
(26)
Biologically Active
Biologically active
(11)
Animal-free
Animal-free
(1)
E. coli
His
13 kD
1 mg/$1,355; 100 µg/$420; 20 µg/$323
E. coli
None
Less than 0.1 ng/µg of protein (less than 1EU/µg).
8.9 kDa
5 µg/$268; 25 µg/$349
E. coli
His-T7
12.9 kDa
10 µg/$291; 50 µg/$502; 100 µg/$802; 200 µg/$1,002; 1 mg/$2,144; 500 µg/$1,668; 5 mg/$3,501; 2 mg/$2,334
E. coli
None
Less than 1.0 EU/µg protein (determined by LAL method).
100 µg/$317; 500 µg/$526; 20 µg/$245
E. coli
None
Biologically active
Less than 0.1 ng/µg of protein (less than 1EU/µg).
8.4 kDa
5 µg/$268; 25 µg/$349
E. coli
None
Biologically active
Less than 0.01 ng/µg of protein (Less than 0.1 EU/µg).
5 µg/$282; 25 µg/$370
E. coli
None
Biologically active
8.9 kDa
5 µg/$282; 100 µg/$957; 500 µg/$1,747
E. coli
None
Biologically active
8.4 kDa
5 µg/$282; 100 µg/$957; 500 µg/$1,747
E. coli
None
Biologically active
9.14kDa
5 µg/$296; 100 µg/$1,116; 500 µg/$2,095
E. coli
His-T7
12.9 kDa
10 µg/$287; 50 µg/$482; 100 µg/$770; 200 µg/$962; 1 mg/$2,094; 500 µg/$1,623; 5 mg/$3,361; 2 mg/$2,284
E. coli
His
13.0 kDa
10 µg/$287; 50 µg/$482; 100 µg/$770; 200 µg/$962; 1 mg/$2,094; 500 µg/$1,623; 5 mg/$3,361; 2 mg/$2,284
Wheat Germ Extract
GST
36.52 kDa
10 µg/$479; 25 µg/$670
E. coli
None
Less than 1.0 EU/µg protein (determined by LAL method).
8.45kD
10 µg/$284; 50 µg/$431; 500 µg/$1,353; 1 mg/$1,725
E. coli
None
Less than 1.0 EU/µg protein (determined by LAL method).
8.9kD
10 µg/$284; 50 µg/$424; 500 µg/$1,353; 1 mg/$1,725
Wheat Germ Extract
GST, N-terminus
2 µg/$439
HEK 293 Cells
Myc-DDK (Flag)
9.1 kDa
20 µg/$1,107
Human Cells
None
Less than 1.0 EU/µg protein (determined by LAL method).
8.5 kDa
100 µg/$666
Human Cells
None
Less than 1.0 EU/µg protein (determined by LAL method).
8 kDa
100 µg/$666; 10 µg/$346
Human Cells
Fc
Less than 1.0 EU/µg protein (determined by LAL method).
35.6 kDa
100 µg/$666
E. coli
None
8.5 kDa
20 µg/$383; 100 µg/$713
HEK 293 Cells
Myc-DDK (Flag)
11.1 kDa
100 µg/$494
Human Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
10.1kD
10 µg/$281; 50 µg/$420; 500 µg/$1,585; 1 mg/$2,157
293T Cells
Myc-DDK (Flag)
11.1 kDa
20 µg/$150
E. coli
78 AA
His
Less than 0.1 EU/µg protein (determined by LAL method).
8.69 kDa
10 mg/$4,268; 5 mg/$3,201; 1 mg/$1,868; 0.5 mg/$1,475; 200 µg/$1,103; 100 µg/$756; 50 µg/$531
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