IL6R / IL6 Receptor

interleukin 6 receptor

IL6R / IL6 Receptor is a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been reported. A pseudogene of this gene is found on chromosome 9.

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Products

Proteins (34)

Type

Native (1)

Over-Expression Lysate (4)

Recombinant (29)

Target

IL6R / IL6 Receptor (34)

Application

Bind (1)

ELISA (1)

Func (1)

SDS-PAGE (3)

Publications

No (34)

Tag

6His, C-terminus (3)

6His, N-terminus (1)

AVI-6His, C-terminus (1)

Fc (1)

Fc, C-terminus (1)

GST (1)

GST, N-terminus (1)

His (10)

His, N-Terminal (2)

His, N-terminus + His, C-terminus (1)

His,C-terminus (2)

Human IgG Fc, C-terminus (1)

Human IgG1 Fc (1)

Mouse IgG2 Fc (1)

Myc-DDK (Flag) (6)

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Species

Human (19)

Mouse (7)

Rat (6)

Source

293T Cells (2)

CHO Cells (3)

E. coli (8)

HEK 293 Cells (7)

Human (3)

Human Cells (5)

Mammalian Cells (1)

Mouse (1)

Sf9 Cells (1)

Wheat Germ Extract (2)

Yeast (1)

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Purification

Purified (11)

Low Endotoxin Level

Low endotoxin level (16)

Biologically Active

Biologically active (5)

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Human IL6R / IL6 Receptor Protein (Recombinant) (aa20-365) - LS-G27205

Source:

CHO Cells

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 0.2 EU/µg protein (determined by LAL method).

Molecular Weight:

54-56 kDa (SDS-PAGE)

Price:

50 µg/$615; 10 µg/$304

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Human IL6R / IL6 Receptor Protein (Recombinant Human IgG Fc, C-terminus) (Met1-Pro365) - LS-G141239

Source:

HEK 293 Cells

Tag:

Human IgG Fc, C-terminus

Application:

SDS-PAGE

Biological Activity:

Biologically active

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

The recombinant human IL6R consists of 464 amino acids and predicts a molecular mass of 52.2 kDa.

Price:

100 µg/$480; 1 mg/$2,333

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Human IL6R / IL6 Receptor Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G70524

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

49.8 kDa

Price:

20 µg/$1,107

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Mouse IL6R / IL6 Receptor Protein (Recombinant Mouse IgG2 Fc) (aa20-357) - LS-G4112

Source:

CHO Cells

Tag:

Mouse IgG2 Fc

Biological Activity:

Biologically active

Endotoxin Level:

Less than 0.06 EU/µg protein (determined by LAL method).

Price:

50 µg/$442

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Human IL6R / IL6 Receptor Protein (Recombinant 6His, C-terminus) (Leu20-Asp358) - LS-G39132

Source:

Human Cells

Tag:

6His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

38.9kD

Price:

10 µg/$288; 50 µg/$442; 500 µg/$1,585; 1 mg/$2,157

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Human IL6R / IL6 Receptor Protein (Recombinant His,C-terminus) (Met1-Pro365) - LS-G47982

Source:

HEK 293 Cells

Tag:

His,C-terminus

Application:

Bind ELISA Func SDS-PAGE

Biological Activity:

Biologically active

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

The soluble form of recombinant human IL6R consists of 357 amino acids and has a predicted molecular mass of 40 kDa. In SDS-PAGE under reducing conditions, it migrates with an apparent molecular mass of 60-65 kDa due to glycosylation.

Price:

100 µg/$472; 1 mg/$2,272

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Human IL6R / IL6 Receptor Protein (Recombinant Human IgG1 Fc) (aa20-359) - LS-G4017

Source:

CHO Cells

Tag:

Human IgG1 Fc

Endotoxin Level:

Less than 0.06 EU/µg protein (determined by LAL method).

Price:

50 µg/$428

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Rat IL6R / IL6 Receptor Protein (Recombinant His) (Met1-Pro364) - LS-G98425

Source:

Human Cells

Tag:

His

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

39.5 kDa

Price:

50 µg/$721

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Rat IL6R / IL6 Receptor Protein (Recombinant His) (aa385-462) - LS-G14315

Source:

E. coli

Tag:

His

Molecular Weight:

10.1 kDa

Price:

10 µg/$287; 50 µg/$482; 100 µg/$770; 200 µg/$962; 1 mg/$2,094; 500 µg/$1,623; 5 mg/$3,361; 2 mg/$2,284

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Rat IL6R / IL6 Receptor Protein (Recombinant His) (aa19-348) - LS-G14318

Source:

E. coli

Tag:

His

Molecular Weight:

38.0 kDa

Price:

10 µg/$287; 50 µg/$482; 100 µg/$770; 200 µg/$962; 1 mg/$2,094; 500 µg/$1,623; 5 mg/$3,361; 2 mg/$2,284

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Human IL6R / IL6 Receptor Protein (Recombinant GST) (Full Length) - LS-G29034

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

77.9 kDa

Price:

2 µg/$439

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Mouse IL6R / IL6 Receptor Protein (Recombinant His,C-terminus) (Ile44-Glu357) - LS-G49372

Source:

HEK 293 Cells

Tag:

His,C-terminus

Application:

SDS-PAGE

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

The recombinant mouse IL6Ra comprises 349 amino acids with a predicted molecular mass of 39 kDa. As a result of glycosylation, it migrates as an approximately 55-60 kDa band in SDS-PAGE under reducing conditions.

Price:

50 µg/$441; 1 mg/$2,551

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Human IL6R / IL6 Receptor Protein (Recombinant GST, N-terminus) (aa21-120) - LS-G58977

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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IL6R / IL6 Receptor Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G99077

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

51.5 kDa

Price:

100 µg/$710

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Human IL6R / IL6 Receptor Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G87339

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

51.5 kDa

Price:

20 µg/$215

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Human IL6R / IL6 Receptor Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G87340

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

38.4 kDa

Price:

20 µg/$150

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IL6R / IL6 Receptor Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G104500

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

38.4 kDa

Price:

100 µg/$494

Select

Human IL6R / IL6 Receptor Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G70525

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

38.4 kDa

Price:

20 µg/$1,107

Select

Human IL6R / IL6 Receptor Protein (Recombinant Fc, C-terminus) - LS-G146156

Source:

Human

Tag:

Fc, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

65.4 kDa

Price:

10 µg/$290; 50 µg/$446

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Human IL6R / IL6 Receptor Protein (Recombinant His, N-terminus + His, C-terminus) - LS-G146204

Source:

E. coli

Tag:

His, N-terminus + His, C-terminus

Molecular Weight:

39.9kDa

Price:

20 µg/$270; 100 µg/$390

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Human IL6R / IL6 Receptor Protein (Recombinant AVI-6His, C-terminus) - LS-G146092

Source:

Human

Tag:

AVI-6His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

41.2 kDa

Price:

20 µg/$428; 100 µg/$910

Select

Mouse IL6R / IL6 Receptor Protein (Recombinant 6His, C-terminus) - LS-G146272

Source:

Human

Tag:

6His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

38.9 kDa

Price:

10 µg/$373; 50 µg/$795

Select

Human IL6R / IL6 Receptor Protein (Recombinant 6His, C-terminus) (Leu20-Asp358) - LS-G139771

Source:

Mammalian Cells

Tag:

6His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

38.9 kDa

Price:

10 µg/$288; 50 µg/$436

Select

Mouse IL6R / IL6 Receptor Protein (Native His, N-Terminal) - LS-G133755

Source:

Mouse

Tag:

His, N-Terminal

Molecular Weight:

18kDa

Price:

10 µg/$291; 50 µg/$502; 200 µg/$1,002; 100 µg/$802; 1 mg/$2,144; 500 µg/$1,668; 5 mg/$3,501; 2 mg/$2,334

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Human IL6R / IL6 Receptor Protein (Recombinant His, N-Terminal) - LS-G27255

Source:

Sf9 Cells

Tag:

His, N-Terminal

Biological Activity:

Biologically active

Endotoxin Level:

Less than 0.2 EU/µg protein (determined by LAL method).

Molecular Weight:

50 kDa (SDS-PAGE)

Price:

50 µg/$402; 10 µg/$262; 1 mg/$1,933

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