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IL6 / Interleukin 6
interleukin 6 (interferon, beta 2)
Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation.
| Gene Name: | interleukin 6 (interferon, beta 2) |
| Family/Subfamily: | Hormone , not assigned-Hormone |
| Synonyms: | IL6, B-cell stimulatory factor 2, BSF-2, BSF2, CTL differentiation factor, Hybridoma growth factor, IFN-beta-2, Interleukin-6, Interleukin BSF-2, IFNB2, B-cell differentiation factor, CDF, HSF, IL-6 |
| Target Sequences: | NM_000600 NP_000591.1 P05231 |
Publications (18)
1
Mammalian target of rapamycin activation underlies HSC defects in autoimmune disease and inflammation in mice. Chen C, Liu Y, Liu Y, Zheng P. The Journal of clinical investigation. 2010 120:4091-101. (Mouse)
[PubMed:20972332]
[PMC:PMC2964994]
Related Antibodies: LS-C7955.
2
Fetal skin as a pro-inflammatory organ: Evidence from a primate model of chorioamnionitis. Boonkasidecha S, Kannan PS, Kallapur SG, Jobe AH, Kemp MW. PloS one. 2017 September;12:e0184938. (Human)
[Full Text Article]
[PubMed:28957335]
[PMC:PMC5619751]
Related Antibodies: LS-B7482.
3
Contribution of the Interleukin-6/STAT-3 Signaling Pathway to Chondrogenic Differentiation of Human Mesenchymal Stem Cells. Kondo M, Yamaoka K, Sakata K, Sonomoto K, Lin L, Nakano K, Tanaka Y. Arthritis & rheumatology (Hoboken, N.J.). 2015 May;67:1250-60. [Full Text Article]
[PubMed:25604648]
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Neuroscience
IL6 / Interleukin 6 Rabbit anti-Human Polyclonal (Internal) Antibody
Human, Monkey
IHC, IHC-P
Unconjugated
50 µg/$440
IL6 / Interleukin 6 Mouse anti-Human Monoclonal (6D9A1) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$460
Neuroscience
IL6 / Interleukin 6 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC-P, WB
Unconjugated
50 µg/$485
Neuroscience
IL6 / Interleukin 6 Mouse anti-Rat Monoclonal (10E5) Antibody
Rat
Flo, IHC, IHC-P, WB
Unconjugated
50 µg/$595
Fast Shipping
IL6 / Interleukin 6 Rabbit anti-Human Polyclonal (Internal) Antibody
Human
IHC, IHC-P
Unconjugated
50 µg/$460
IL6 / Interleukin 6 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
IL6 / Interleukin 6 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
IL6 / Interleukin 6 Rat anti-Mouse Monoclonal (Azide-free) Antibody
Mouse
ELISA, Flo, IHC, Neut, WB
Unconjugated, Azide-free
500 µg/$786
IL6 / Interleukin 6 Rabbit anti-Mouse Polyclonal Antibody
Mouse
ELISA, IHC, WB
Unconjugated
100 µg/$567
IL6 / Interleukin 6 Mouse anti-Human Monoclonal Antibody
Human
ELISA, WB
Unconjugated
500 µg/$326
IL6 / Interleukin 6 Rabbit anti-Sheep Polyclonal (Serum) Antibody
Sheep
ELISA, WB
Unconjugated, Serum
0.1 ml/$570
IL6 / Interleukin 6 Mouse anti-Human Monoclonal (OTI2C9) Antibody
Human
WB
Unconjugated
100 µl/$434
IL6 / Interleukin 6 Guinea pig anti-Rabbit Polyclonal (aa27-241) Antibody
Rabbit
WB
Unconjugated
100 µl/$306; 200 µl/$347; 500 µl/$484; 1 ml/$553; 2 ml/$737; 5 ml/$1,206
IL6 / Interleukin 6 Rabbit anti-Dog Polyclonal (aa18-207) (APC) Antibody
Dog
WB
APC Conjugated
100 µl/$412; 200 µl/$499; 500 µl/$869; 1 ml/$1,030; 2 ml/$1,345; 5 ml/$2,521
IL6 / Interleukin 6 Rabbit anti-Human Polyclonal (aa27-55) Antibody
Human
Flo, IHC, IHC-P, WB
Unconjugated
400 µl/$393
IL6 / Interleukin 6 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA, IHC, WB
HRP Conjugated
50 µg/$294; 100 µg/$360
Sandwich
96-Well Microplate
Mouse
0.82 - 600 pg/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$534
Sandwich
96-Well Microplate
Human
3 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$534
CHO Cells
Human Mutant IgG1 Fc
Less than 0.06 EU/µg protein (determined by LAL method).
50 µg/$358
Sandwich
96-Well Microplate
Pig
40.96 - 10000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$534
Sandwich
96-Well Strip Plate
Human
7.8 - 500 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$600
Sandwich
96-Well Strip Plate
Rat
7.8 - 500 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$573
Sandwich
96-Well Strip Plate
Rabbit
3.12 - 200 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$715
Sandwich
96-Well Strip Plate
Rat
1.56 - 100 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$602
Sandwich
96-Well Strip Plate
Human
3.12 - 200 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$659
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