IL4

interleukin 4

IL4 is a pleiotropic cytokine produced by activated T cells. This cytokine is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. This gene, IL3, IL5, IL13, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL13. This gene, IL13 and IL5 are found to be regulated coordinately by several long-range regulatory elements in an over 120 kilobase range on the chromosome. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

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Products

Proteins (72)

Type

Over-Expression Lysate (2)

Recombinant (70)

Target

IL4 (72)

Format

Animal-free (2)

Publications

No (72)

Tag

10His-B2M, N-terminus + Myc, C-terminus (1)

6His, C-terminus (5)

6His, N-terminus (3)

6His-SUMO, N-terminus (1)

Fc, C-terminus (1)

GST (1)

GST, N-terminus (1)

His (9)

His, C-Terminal (1)

His, N-Terminal (5)

His,C-terminus (1)

His-GST (2)

His-T7 (3)

Human IgG1 Fc, C-terminus (1)

Human Mutant IgG1 Fc (1)

Mouse Mutant IgG2a Fc (1)

Myc-DDK (Flag) (3)

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Species

Bovine (1)

Chicken (1)

Crab-eating macaque (1)

Dog (2)

Human (38)

Mouse (16)

Pig (3)

Rabbit (2)

Rat (4)

Rhesus monkey (1)

Sheep (2)

more less

Source

293F Cells (2)

293T Cells (1)

CHO Cells (7)

E. coli (36)

HEK 293 Cells (6)

Human (4)

Human Cells (2)

Mammalian Cells (5)

Wheat Germ Extract (2)

Yeast (4)

Purification

Purified (24)

Low Endotoxin Level

Low endotoxin level (38)

Biologically Active

Biologically active (25)

Animal-free

Animal-free (2)

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Human IL4 Protein (Recombinant Human IgG1 Fc, C-terminus) (aa1-153) - LS-G4021

Source:

CHO Cells

Tag:

Human IgG1 Fc, C-terminus

Endotoxin Level:

Less than 0.06 EU/µg protein (determined by LAL method).

Molecular Weight:

43 kDa (predicted)

Price:

50 µg/$428; 10 µg/$337

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Crab-eating macaque IL4 Protein (Recombinant 6His, N-terminus) (aa25-153) - LS-G57385

Source:

Yeast

Tag:

6His, N-terminus

Price:

1 mg/$1,973; 100 µg/$679; 20 µg/$429

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Mouse IL4 Protein (Recombinant) - LS-G27079

Source:

CHO Cells

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 0.2 EU/µg protein (determined by LAL method).

Molecular Weight:

15 kDa (SDS-PAGE)

Price:

50 µg/$342; 10 µg/$286; 1 mg/$1,612

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Rhesus monkey IL4 Protein (Recombinant) (aa25-153) - LS-G5753

Source:

E. coli

Tag:

None

Biological Activity:

Biologically active

Molecular Weight:

14.9 kDa

Price:

5 µg/$267; 20 µg/$351; 100 µg/$874; 250 µg/$1,382; 1 mg/$2,839; 500 µg/$1,917

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Mouse IL4 Protein (Recombinant) - LS-G136723

Source:

E. coli

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

13.4 kDa

Price:

50 µg/$487; 10 µg/$303; 1 mg/$2,837; 500 µg/$1,987

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Human IL4 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G69813

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

14.9 kDa

Price:

20 µg/$1,107

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Mouse IL4 Protein (Recombinant) (aa21-140) - LS-G5876

Source:

E. coli

Tag:

None

Biological Activity:

Biologically active

Molecular Weight:

13.5 kDa

Price:

5 µg/$282; 100 µg/$1,030; 500 µg/$1,891

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Chicken IL4 Protein (Recombinant His, N-Terminal) (aa26-136) - LS-G23885

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

16.2 kDa

Price:

10 µg/$284; 50 µg/$460; 100 µg/$735; 200 µg/$917; 1 mg/$2,037; 500 µg/$1,571; 5 mg/$3,207; 2 mg/$2,225

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Rat IL4 Protein (Recombinant His) - LS-G23887

Source:

HEK 293 Cells

Tag:

His

Molecular Weight:

15.5 kDa

Price:

10 µg/$323; 50 µg/$702; 100 µg/$1,043

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Pig IL4 Protein (Recombinant) - LS-G27055

Source:

CHO Cells

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 0.2 EU/µg protein (determined by LAL method).

Molecular Weight:

15 kDa (SDS-PAGE)

Price:

50 µg/$551; 10 µg/$304; 1 mg/$3,157

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Sheep IL4 Protein (Recombinant 6His, N-terminus) (Full Length) - LS-G136598

Source:

Yeast

Tag:

6His, N-terminus

Molecular Weight:

14.6 kDa

Price:

100 µg/$679; 20 µg/$429; 1 mg/$1,973

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Mouse IL4 Protein (Recombinant) - LS-G209

Source:

E. coli

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 0.1 ng/µg of protein (less than 1EU/µg).

Molecular Weight:

13.5 kDa

Price:

5 µg/$268; 20 µg/$349

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Mouse IL4 Protein (Recombinant) - LS-G3698

Source:

E. coli

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 0.01 ng/µg of protein (Less than 0.1 EU/µg).

Price:

5 µg/$281; 20 µg/$369

• Unmodified
• Animal-free

• Unmodified
• Animal-free

Select

Rat IL4 Protein (Recombinant) - LS-G396

Source:

E. coli

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 0.1 ng/µg of protein (less than 1EU/µg).

Molecular Weight:

14.0 kDa

Price:

5 µg/$268; 20 µg/$349

Select

Human IL4 Protein (Recombinant His) - LS-G3475

Source:

E. coli

Tag:

His

Biological Activity:

Biologically active

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Price:

50 µg/$511; 250 µg/$1,348; 10 µg/$311

Select

Human IL4 Protein (Recombinant) - LS-G157

Source:

E. coli

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 0.1 ng/µg of protein (less than 1EU/µg).

Molecular Weight:

15.1 kDa

Price:

5 µg/$268; 20 µg/$349

Select

Human IL4 Protein (Recombinant) - LS-G3658

Source:

E. coli

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 0.01 ng/µg of protein (Less than 0.1 EU/µg).

Price:

5 µg/$281; 20 µg/$369

• Unmodified
• Animal-free

• Unmodified
• Animal-free

Select

Human IL4 Protein (Recombinant) (aa25-153) - LS-G5719

Source:

E. coli

Tag:

None

Biological Activity:

Biologically active

Molecular Weight:

15.0 kDa

Price:

5 µg/$282; 100 µg/$1,030; 500 µg/$1,891

Select

Human IL4 Protein (Recombinant GST) (Full Length) - LS-G29030

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

42.46 kDa

Price:

2 µg/$439

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Human IL4 Protein (Recombinant) (His25-Ser153) - LS-G38595

Source:

E. coli

Tag:

None

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

15.1kD

Price:

10 µg/$297; 50 µg/$468; 500 µg/$1,353; 1 mg/$1,725

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Mouse IL4 Protein (Recombinant) (His23-Ser140) - LS-G40073

Source:

E. coli

Tag:

None

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

13.4kD

Price:

10 µg/$281; 50 µg/$420; 500 µg/$1,585; 1 mg/$2,157

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Mouse IL4 Protein (Recombinant 6His, C-terminus) (His21-Ser140) - LS-G40128

Source:

Human Cells

Tag:

6His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

14.6kD

Price:

10 µg/$288; 50 µg/$442; 500 µg/$1,585; 1 mg/$2,157

Select

Bovine IL4 Protein (Recombinant) - LS-G37655

Tag:

None

Molecular Weight:

12.6 kD

Price:

20 µg/$900

Select

Human IL4 Protein (Recombinant) (aa25-153) - LS-G55912

Source:

Human

Tag:

None

Price:

50 µg/$522; 10 µg/$294; 200 µg/$1,034; 100 µg/$832; 1 mg/$2,192; 500 µg/$1,712; 5 mg/$3,641; 2 mg/$2,383

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Human IL4 Protein (Recombinant) (aa25-147) - LS-G55913

Source:

Human

Tag:

None

Molecular Weight:

15.4kDa

Price:

50 µg/$702; 10 µg/$323; 200 µg/$1,300; 100 µg/$1,098; 1 mg/$2,565; 500 µg/$2,063; 5 mg/$4,915; 2 mg/$2,757

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