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IL3RA / CD123
interleukin 3 receptor, alpha (low affinity)
IL3RA / CD123 is an interleukin 3 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL3 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL3. This gene and the gene encoding the colony stimulating factor 2 receptor alpha chain (CSF2RA) form a cytokine receptor gene cluster in a X-Y pseudoautosomal region on chromosomes X or Y. Alternatively spliced transcript variants encoding distinct isoforms have been found.
| Gene Name: | interleukin 3 receptor, alpha (low affinity) |
| Family/Subfamily: | Interleukin |
| Synonyms: | IL3RA, CD123 antigen, IL-3 receptor subunit alpha, IL-3R subunit alpha, IL3R, IL3RY, CD123, HIL-3Ra, IL-3R-alpha, IL-3RA, IL3RAY, IL3RX |
| Target Sequences: | NM_002183 NP_002174.1 P26951 |
Publications (1)
1
Basophils and the T helper 2 environment can promote the development of lupus nephritis. Charles N, Hardwick D, Daugas E, Illei GG, Rivera J. Nature medicine. 2010 16:701-7.
[PubMed:20512127]
[PMC:PMC2909583]
Related Antibodies: LS-C40981.
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(98)
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IL3RA / CD123 Mouse anti-Human Monoclonal (aa200-305) (10B8E7) Antibody
Human
ELISA, Flo, IF, IHC, IHC-P, WB
Unconjugated
50 µl/$460
IL3RA / CD123 Mouse anti-Human Monoclonal (6H6) Antibody
Human
Flo, IHC, IHC-Fr, IP, WB
Unconjugated
100 µg/$276
IL3RA / CD123 Mouse anti-Human Monoclonal (aa200-305) (8E11C5) Antibody
Human
ELISA, Flo, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$459
IL3RA / CD123 Mouse anti-Human Monoclonal (6H6) Antibody
Human
Flo, IHC, IHC-Fr, IHC-P
Unconjugated
25 µg/$215; 100 µg/$255
IL3RA / CD123 Mouse anti-Human Monoclonal Antibody
Human
IHC, IHC-Fr, IHC-P
Unconjugated
0.1 ml/$332
IL3RA / CD123 Mouse anti-Human Monoclonal (Ready-to-Use) Antibody
Human
IHC-Fr, IHC-P
Unconjugated, Ready-to-Use
3 ml/$367
IL3RA / CD123 Goat anti-Human Polyclonal Antibody
Human
IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$460
E. coli
His, N-Terminal
17.3 kDa
10 µg/$285; 50 µg/$470; 100 µg/$750; 200 µg/$937; 1 mg/$2,063; 500 µg/$1,594; 5 mg/$3,277; 2 mg/$2,252
Sandwich
96-Well Strip Plate
Human
31.2 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
HEK 293 Cells
Myc-DDK (Flag)
41.2 kDa
20 µg/$1,107
IL3RA / CD123 Mouse anti-Human Monoclonal (6H6) Antibody
Mouse, Human
Flo, IHC-Fr, IHC-P
Unconjugated
100 µg/$304
IL3RA / CD123 Mouse anti-Human Monoclonal (IL3RA/1531) Antibody
Human
IHC-P
Unconjugated
20 µg/$371; 100 µg/$574
IL3RA / CD123 Mouse anti-Human Monoclonal (Azide-free, BSA-free) (IL3RA/1531) Antibody
Human
IHC-P
Unconjugated, Azide-free, BSA-free
100 µg/$574
IL3RA / CD123 Rabbit anti-Mouse Polyclonal (aa167-331) Antibody
Mouse
WB
Unconjugated
100 µl/$306; 200 µl/$347; 500 µl/$484; 1 ml/$553; 2 ml/$737; 5 ml/$1,206
IL3RA / CD123 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
IL3RA / CD123 Rabbit anti-Mouse Polyclonal (aa17-166) Antibody
Mouse
WB
Unconjugated
100 µl/$306; 200 µl/$347; 500 µl/$484; 1 ml/$553; 2 ml/$737; 5 ml/$1,206
IL3RA / CD123 Rabbit anti-Human Polyclonal (aa51-100) Antibody
Human
WB
Unconjugated
100 µl/$424
IL3RA / CD123 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
IL3RA / CD123 Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Rat, Human
WB
Unconjugated
100 µl/$299
IL3RA / CD123 Rabbit anti-Human Polyclonal (aa19-157) (PE) Antibody
Human
WB
PE Conjugated
100 µl/$396; 200 µl/$476; 500 µl/$815; 1 ml/$969; 2 ml/$1,240; 5 ml/$2,325
Wheat Germ Extract
GST, N-terminus
35.75 kDa
10 µg/$479; 25 µg/$670
Human Cells
His
Less than 1.0 EU/µg protein (determined by LAL method).
35.9 kDa
100 µg/$793; 1 mg/$4,191
IL3RA / CD123 Mouse anti-Human Monoclonal (6H6) Antibody
Human
Flo, IHC-Fr, IP, WB
Unconjugated
0.1 mg/$302
IL3RA / CD123 Mouse anti-Human Monoclonal (PE) (6H6) Antibody
Human
Flo, IHC-Fr, IP, WB
PE Conjugated
100 Tests/$365
Fast Shipping
IL3RA / CD123 Rabbit anti-Human Polyclonal Antibody
IHC-P
Unconjugated
50 µg/$460
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