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IL32 is a member of the cytokine family. The protein contains a tyrosine sulfation site, 3 potential N-myristoylation sites, multiple putative phosphorylation sites, and an RGD cell-attachment sequence. Expression of this protein is increased after the activation of T-cells by mitogens or the activation of NK cells by IL-2. This protein induces the production of TNFalpha from macrophage cells. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Gene Name: | interleukin 32 |
Synonyms: | IL32, IL-32alpha, IL-32delta, IL-32gamma, Interleukin 32, Interleukin-32 small, Interleukin-32 theta, Interleukin-32, Interleukin-32 eta, Natural killer cells protein 4, IL-32beta, TAIF, TAIFb, TAIFc, TAIFd, NK4, IL-32, TAIFa |
Target Sequences: | NM_004221 NP_004212.4 P24001 |
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