IL27RA

interleukin 27 receptor, alpha

Upon antigen challenge, T-helper cells differentiate into two functional distinct subsets, Th1 and Th2. Th1 cells produce IL-2, IFN-g and lymphotoxin-b that augment cell mediated immune response while Th2 cells secrete IL-4, IL-5, and IL-10 that enhance humoral immunity. The function of T-helper cells is regulated by cytokines. A novel cytokine receptor was recently identified and cloned. It is a new member in the type I cytokine receptor family and designated TCCR for T-cell cytokine receptor and WSX-1. TCCR deficient mice had impaired Th1 responses to protein antigen challenge, including decreased levels of IFN-g and Th1-dependent antibody IgG2a. TCCR is predominately expressed in thymus, spleen, lymph notes and peripheral blood leukocytes.

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Products

Proteins (10)

Type

Over-Expression Lysate (3)

Recombinant (7)

Target

IL27RA (10)

Publications

No (10)

Tag

6His, N-terminus (1)

Fc, C-terminus (1)

GST, N-terminus (1)

His, N-Terminal (1)

His-T7 (3)

Myc-DDK (Flag) (3)

Species

Human (7)

Mouse (1)

Rat (1)

Source

293T Cells (1)

E. coli (4)

HEK 293 Cells (4)

Wheat Germ Extract (1)

Purification

Purified (1)

Low Endotoxin Level

Low endotoxin level (1)

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Human IL27RA Protein (Recombinant His, N-Terminal) (Gln33-Lys516) - LS-G96964

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

53 kDa

Price:

10 µg/$265; 200 µg/$484; 50 µg/$315

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Human IL27RA Protein (Recombinant GST, N-terminus) (aa33-132) - LS-G61139

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human IL27RA Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G68816

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

69.3 kDa

Price:

20 µg/$1,107

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Human IL27RA Protein (Over-Expression Lysate 6His, N-terminus) (Gln33-Lys516) - LS-G26780

Source:

HEK 293 Cells

Tag:

6His, N-terminus

Molecular Weight:

53 kDa

Price:

100 µg/$298

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Human IL27RA Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G83176

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

69.3 kDa

Price:

20 µg/$150

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IL27RA Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G116371

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

69.3 kDa

Price:

100 µg/$494

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Human IL27RA Protein (Recombinant Fc, C-terminus) (Met1-Arg514) - LS-G138090

Source:

HEK 293 Cells

Tag:

Fc, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

79 kDa

Price:

100 µg/$721

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Mouse IL27RA Protein (Recombinant His-T7) (aa117-350) - LS-G13446

Source:

E. coli

Tag:

His-T7

Molecular Weight:

29.8 kDa

Price:

10 µg/$289; 50 µg/$492; 100 µg/$785; 200 µg/$982; 1 mg/$2,119; 500 µg/$1,646; 5 mg/$3,431; 2 mg/$2,309

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Human IL27RA Protein (Recombinant His-T7) (aa123-343) - LS-G13448

Source:

E. coli

Tag:

His-T7

Molecular Weight:

28.2 kDa

Price:

10 µg/$287; 50 µg/$482; 100 µg/$770; 200 µg/$962; 1 mg/$2,094; 500 µg/$1,623; 5 mg/$3,361; 2 mg/$2,284

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Rat IL27RA Protein (Recombinant His-T7) (aa93-273) - LS-G13450

Source:

E. coli

Tag:

His-T7

Molecular Weight:

24.4 kDa

Price:

10 µg/$287; 50 µg/$482; 100 µg/$770; 200 µg/$962; 1 mg/$2,094; 500 µg/$1,623; 5 mg/$3,361; 2 mg/$2,284

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