IL24

interleukin 24

IL24 is a member of the IL10 family of cytokines. It was identified as a gene induced during terminal differentiation in melanoma cells. The protein encoded by this gene can induce apoptosis selectively in various cancer cells. Overexpression of this gene leads to elevated expression of several GADD family genes, which correlates with the induction of apoptosis. The phosphorylation of mitogen-activated protein kinase 14 (MAPK7/P38), and heat shock 27kDa protein 1 (HSPB2/HSP27) are found to be induced by this gene in melanoma cells, but not in normal immortal melanocytes. Alternatively spliced transcript variants encoding distinct isoforms have been reported.

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Products

Proteins (14)

Type

Over-Expression Lysate (2)

Recombinant (12)

Target

IL24 (14)

Application

SDS-PAGE (2)

Publications

No (13)

Yes (1)

Tag

GST (2)

GST, N-terminus (1)

His, C-Terminal (1)

His, N-Terminal (2)

His,C-terminus (1)

His-GST (1)

Human IgG1 Fc (1)

Mouse IgG1 Fc, C-terminus (1)

Myc-DDK (Flag) (3)

Species

Human (12)

Rat (1)

Source

293T Cells (1)

CHO Cells (3)

E. coli (3)

HEK 293 Cells (4)

Wheat Germ Extract (3)

Purification

Purified (5)

Low Endotoxin Level

Low endotoxin level (5)

Biologically Active

Biologically active (2)

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Human IL24 Protein (Recombinant His, C-Terminal) - LS-G187

Source:

CHO Cells

Tag:

His, C-Terminal

Endotoxin Level:

Less than 0.1 ng/µg of protein (less than 1EU/µg).

Molecular Weight:

18.9 kDa

Price:

5 µg/$268; 20 µg/$349

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Human IL24 Protein (Recombinant His, N-Terminal) (aa51-206) - LS-G14688

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

19.5 kDa

Price:

10 µg/$291; 50 µg/$502; 100 µg/$802; 200 µg/$1,002; 1 mg/$2,144; 500 µg/$1,668; 5 mg/$3,501; 2 mg/$2,334

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Human IL24 Protein (Recombinant GST) (Full Length) - LS-G32450

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

48.51 kDa

Price:

10 µg/$479; 25 µg/$670

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Human IL24 Protein (Recombinant His,C-terminus) (Met1-Leu207) - LS-G47159

Source:

HEK 293 Cells

Tag:

His,C-terminus

Application:

SDS-PAGE

Biological Activity:

Biologically active

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

The secreted recombinant human IL24 consists of 166 amino acids and has a predicted molecular mass of 19.5 kDa. As a result of different glycosylation, the apparent molecular mass of rhIL24 is approximately 35 kDa in SDS-PAGE under reducing conditions.

Price:

50 µg/$364; 1 mg/$2,003

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Human IL24 Protein (Recombinant GST, N-terminus) (aa58-167) - LS-G61708

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human IL24 Protein (Recombinant His, N-Terminal) (GLy51-Leu206) - LS-G132799

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

18kDa

Price:

10 µg/$295; 50 µg/$530; 200 µg/$1,045; 100 µg/$847; 1 mg/$2,211; 500 µg/$1,728; 5 mg/$3,697; 2 mg/$2,402

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Human IL24 Protein (Recombinant Human IgG1 Fc) (aa53-207) - LS-G4026

Source:

CHO Cells

Tag:

Human IgG1 Fc

Endotoxin Level:

Less than 0.06 EU/µg protein (determined by LAL method).

Price:

25 µg/$491

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Human IL24 Protein (Recombinant GST) (Full Length) - LS-G32453

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

50.2 kDa

Price:

2 µg/$439

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Human IL24 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G77255

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

23.91 kDa

Price:

20 µg/$150

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Human IL24 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G66249

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

18.4 kDa

Price:

20 µg/$1,107

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IL24 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G115047

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

23.91 kDa

Price:

100 µg/$494

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Human IL24 Protein (Recombinant Mouse IgG1 Fc, C-terminus) (Met1-Leu207) - LS-G141211

Source:

HEK 293 Cells

Tag:

Mouse IgG1 Fc, C-terminus

Application:

SDS-PAGE

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

The recombinant human IL24 consists 389 amino acids and predicts a molecular mass of 44.6 kDa.

Price:

50 µg/$364

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Human IL24 Protein (Recombinant) - LS-G131333

Source:

CHO Cells

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

~18.5 kDa

Price:

10 µg/$432

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Rat IL24 Protein (Recombinant His-GST) (aa29-183) - LS-G14689

(4.0) Rating

(1) Publication(s)

Source:

E. coli

Tag:

His-GST

Molecular Weight:

45.1 kDa

Price:

10 µg/$297; 50 µg/$542; 100 µg/$865; 200 µg/$1,065; 1 mg/$2,239; 500 µg/$1,755; 5 mg/$3,781; 2 mg/$2,430

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