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IL24

interleukin 24

IL24 is a member of the IL10 family of cytokines. It was identified as a gene induced during terminal differentiation in melanoma cells. The protein encoded by this gene can induce apoptosis selectively in various cancer cells. Overexpression of this gene leads to elevated expression of several GADD family genes, which correlates with the induction of apoptosis. The phosphorylation of mitogen-activated protein kinase 14 (MAPK7/P38), and heat shock 27kDa protein 1 (HSPB2/HSP27) are found to be induced by this gene in melanoma cells, but not in normal immortal melanocytes. Alternatively spliced transcript variants encoding distinct isoforms have been reported.

Gene Name: interleukin 24
Family/Subfamily: Interleukin
Synonyms: IL24, FISP, IL10B, IL-24, IL-4-induced secreted protein, Interleukin 24, Interleukin-24, Melanocyte-associated Mda-7, Mob-5, ST16, Mda-7, MDA7, MOB5, C49A
Target Sequences: NM_006850 NP_006841.1 Q13007

Publications (1)

1
Interleukin-24 protects against liver injury in mouse models. Hsiao-Hsuan Wang, Jian-Hao Huang, Min-Hao Sue, Wei-Chih Ho, Yu-Hsiang Hsu, Kung-Chao Chang, Ming-Shi Chang. EBioMedicine. 2021 February;64:103213. [Full Text Article] [PubMed:33508745] [PMC:PMC7841303]

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Products
Antibodies (68)
Primary (68)
IL24 (68)
Human (51)
Mouse (2)
Rat (18)
Chimpanzee (3)
Monkey (1)
Orangutan (3)
IHC (10)
IHC-P (1)
WB (59)
Flo (1)
ELISA (18)
Peptide-ELISA (2)
rabbit (49)
mouse (19)
Product Group
IHCPlus (1)
IgG (27)
IgG1 (10)
IgG2a,k (1)
IgG2b,k (8)
monoclonal mc (20)
polyclonal pc (48)
101 (1)
2B5 (1)
OTI3C5 (2)
OTI4D1 (2)
OTI4E1 (2)
OTI4H4 (2)
OTI5C8 (2)
APC (3)
APC Conjugated (5)
Azide-free (1)
Biotin Conjugated (7)
Carrier-free (5)
Cy3 Conjugated (3)
Cy7 Conjugated (3)
FITC Conjugated (7)
HRP Conjugated (7)
PE Conjugated (5)
Preservative Free (2)
Unconjugated (31)
aa52-206 (10)
aa29-183 (8)
aa51-206 (8)
aa139-168 (7)
C-Terminus (4)
131-180 aa, Internal (1)
aa100-150 (1)
aa142-206 (1)
No (68)
IL24 Antibody - Anti-IL-24 antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
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IL24 Rabbit anti-Human Polyclonal (aa100-150) Antibody
Human, Monkey
Flo, IHC, IHC-P, WB
Unconjugated
0.05 mg/$460
IL24 Antibody - Detection limit for recombinant GST tagged IL24 is 0.1 ng/ml as a capture antibody.
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IL24 Mouse anti-Human Monoclonal (2B5) Antibody
Human
ELISA
Unconjugated
100 µg/$423
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IL24 Rabbit anti-Human Monoclonal (Preservative Free) (101) Antibody
Human
ELISA
Unconjugated, Preservative Free
100 µl/$412
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IL24 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA
FITC Conjugated
50 µg/$294; 100 µg/$360
IL24 Antibody - Immunohistochemical staining of paraffin-embedded Human pancreas tissue within the normal limits using anti-IL24 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer. (pH8.5) at 120°C for 3 min. (1:2000)
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IL24 Mouse anti-Human Monoclonal (aa52-206) (OTI3C5) Antibody
Human
IHC, WB
Unconjugated
100 µl/$434
IL24 Antibody - Immunohistochemical staining of paraffin-embedded Human pancreas tissue within the normal limits using anti-IL24 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer. (pH8.5) at 120°C for 3 min. (1:2000)
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IL24 Mouse anti-Human Monoclonal (aa52-206) (Carrier-free) (OTI3C5) Antibody
Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
IL24 Antibody - Immunohistochemical staining of paraffin-embedded Human pancreas tissue within the normal limits using anti-IL24 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer. (pH8.5) at 120°C for 3 min. (1:2000)
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IL24 Mouse anti-Human Monoclonal (aa52-206) (OTI4H4) Antibody
Human
IHC, WB
Unconjugated
100 µl/$434
IL24 Antibody - Immunohistochemical staining of paraffin-embedded Human pancreas tissue within the normal limits using anti-IL24 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer. (pH8.5) at 120°C for 3 min. (1:2000)
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IL24 Mouse anti-Human Monoclonal (aa52-206) (Carrier-free) (OTI4H4) Antibody
Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
IL24 Antibody - Immunohistochemical staining of paraffin-embedded Human pancreas tissue within the normal limits using anti-IL24 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer. (pH8.5) at 120°C for 3 min. (1:150)
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IL24 Mouse anti-Human Monoclonal (aa52-206) (OTI4E1) Antibody
Human
IHC, WB
Unconjugated
100 µl/$434
IL24 Antibody - Immunohistochemical staining of paraffin-embedded Human pancreas tissue within the normal limits using anti-IL24 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer. (pH8.5) at 120°C for 3 min. (1:150)
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IL24 Mouse anti-Human Monoclonal (aa52-206) (Carrier-free) (OTI4E1) Antibody
Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
IL24 Antibody - 1:100 staining human Melanoma tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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IL24 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
IL24 Antibody - Western blot analysis of extracts of M21 cell and mouse liver.
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IL24 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat
IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
IL24 Antibody - Immunohistochemistry of paraffin-embedded Human cervical cancer tissue  using IL24 Polyclonal Antibody at dilution of 1:30(×200)
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IL24 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
Select
IL24 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$341
Select
IL24 Rabbit anti-Human Polyclonal (aa139-168) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
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IL24 Rabbit anti-Human Polyclonal (aa139-168) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
Select
IL24 Rabbit anti-Human Polyclonal (aa139-168) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
Select
IL24 Rabbit anti-Human Polyclonal (aa139-168) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
Select
IL24 Rabbit anti-Human Polyclonal (aa139-168) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
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IL24 Rabbit anti-Human Polyclonal (aa139-168) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
IL24 Antibody - Western blot of MDA-7 antibody
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IL24 Rabbit anti-Human Polyclonal (131-180 aa, Internal) Antibody
Human
ELISA, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
IL24 Antibody - Western blot analysis of lysate from 293 cells, using IL24 Antibody.
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IL24 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
IL24 Antibody - All lanes : Anti-IL24 Antibody at 1:2000 dilution Lane 1: HeLa whole cell lysates Lane 2: Jurkat whole cell lysates Lane 3: K562 whole cell lysates Lane 4: A431 whole cell lysates Lysates/proteins at 20 ug per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution Predicted band size : 24 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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IL24 Rabbit anti-Human Polyclonal Antibody
Human
Peptide-ELISA, WB
Unconjugated
400 µl/$393
IL24 Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control. (Left lane) or pCMV6-ENTRY IL24. (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates. (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-IL24. (1:2000)
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IL24 Mouse anti-Human Monoclonal (aa52-206) (Carrier-free) (OTI5C8) Antibody
Human
WB
Unconjugated, Carrier-free
100 µg/$511
IL24 Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control. (Left lane) or pCMV6-ENTRY IL24. (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates. (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-IL24. (1:2000)
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IL24 Mouse anti-Human Monoclonal (aa52-206) (Carrier-free) (OTI4D1) Antibody
Human
WB
Unconjugated, Carrier-free
100 µg/$511
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).