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IL23A / IL-23 p19

interleukin 23, alpha subunit p19

Associates with IL12B to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis.

Gene Name: interleukin 23, alpha subunit p19
Family/Subfamily: Interleukin
Synonyms: IL23A, IL-23 subunit alpha, IL-23A, Interleukin 23 p19 subunit, Interleukin-23 subunit alpha, IL23P19, Interleukin-23 subunit p19, p19, SGRF, IL-23, IL-23 p19, IL-23-A, IL-23p19
Target Sequences: NM_016584 NP_057668.1 Q9NPF7

Publications (4)

1
The involvement of IL-23 and the Th17 pathway in periodontitis. Ohyama H, Kato-Kogoe N, Kuhara A, Nishimura F, Nakasho K, Yamanegi K, Yamada N, Hata M, Yamane J, Terada N. Journal of dental research. 2009 88:633-8. [PubMed:19605880] Related Antibodies: LS-B3708.
2
Systemic and local interleukin-17 and linked cytokines associated with Sjgren's syndrome immunopathogenesis. Katsifis GE, Rekka S, Moutsopoulos NM, Pillemer S, Wahl SM. The American journal of pathology. 2009 175:1167-77. [PubMed:19700754] [PMC:PMC2731135] Related Antibodies: LS-B3708.
3
Proteasome inhibitors prevent caspase-1-mediated disease in rodents challenged with anthrax lethal toxin. Muehlbauer SM, Lima H, Goldman DL, Jacobson LS, Rivera J, Goldberg MF, Palladino MA, Casadevall A, Brojatsch J. The American journal of pathology. 2010 177:735-43. [PubMed:20595632] [PMC:PMC2913046] Related Antibodies: LS-B3708.
4
Epigenetic control of IL-23 expression in keratinocytes is important for chronic skin inflammation. Li H, Yao Q, Mariscal AG, Wu X, Hülse J, Pedersen E, Helin K, Waisman A, Vinkel C, Thomsen SF, Avgustinova A, Benitah SA, Lovato P, Norsgaard H, Mortensen MS, Veng L, Rozell B, Brakebusch C. Nature communications. 2018 April;9:1420. (Human) [Full Text Article] [PubMed:29650963] [PMC:PMC5897363] Related Antibodies: LS-B573.
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IL23A / IL-23 p19 (23)
Human (4)
Mouse (6)
Rat (6)
Chicken (2)
Monkey (1)
Pig (3)
Rabbit (1)
12 x 8-Well Microstrips (1)
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96-Well Strip Plate (18)
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Cell Culture Supernatants (7)
Cell Lysates (4)
Plasma (19)
Serum (19)
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IL23A / IL-23 p19 ELISA Kit
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Sandwich
96-Well Strip Plate
Rat
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$715
IL23A / IL-23 p19 ELISA Kit
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Sandwich
96-Well Strip Plate
Human
31.2 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates
1 Plate/$590
IL23A / IL-23 p19 ELISA Kit
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Sandwich
96-Well Strip Plate
Human
31.2 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$585
IL23A / IL-23 p19 ELISA Kit
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Sandwich
96-Well Strip Plate
Human
31.2 - 500 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$764
IL23A / IL-23 p19 ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$590
IL23A / IL-23 p19 ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
7.8 - 500 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$544
IL23A / IL-23 p19 ELISA Kit
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Sandwich
96-Well Strip Plate
Rat
31.2 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$585
IL23A / IL-23 p19 ELISA Kit
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Sandwich
96-Well Microplate
Rat
15.625 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$586
IL23A / IL-23 p19 ELISA Kit
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Custom
96-Well Strip Plate
Pig
Colorimetric - 450nm (TMB)
1 Plate/$669
IL23A / IL-23 p19 ELISA Kit
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Custom
96-Well Strip Plate
Mouse
Colorimetric - 450nm (TMB)
1 Plate/$585
IL23A / IL-23 p19 ELISA Kit
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Sandwich
96-Well Strip Plate
Pig
46.875 - 3000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
IL23A / IL-23 p19 ELISA Kit
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Sandwich
96-Well Strip Plate
Rat
31.2 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
IL23A / IL-23 p19 ELISA Kit
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Sandwich CLIA
12 x 8-Well Microstrips
Mouse
7.813 - 500 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$656
IL23A / IL-23 p19 ELISA Kit
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Sandwich
96-Well Strip Plate
Chicken
15.625 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
IL23A / IL-23 p19 ELISA Kit
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Sandwich
96-Well Microplate
Rat
0.82 - 200 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$635
IL23A / IL-23 p19 ELISA Kit
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Sandwich
96-Well Strip Plate
Human
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$968
IL23A / IL-23 p19 ELISA Kit
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Sandwich
96-Well Strip Plate
Pig
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$968
IL23A / IL-23 p19 ELISA Kit
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Sandwich
96-Well Strip Plate
Monkey
39.063 - 2500 pg/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
IL23A / IL-23 p19 ELISA Kit
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Sandwich
96-Well Strip Plate
Rabbit
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
IL23A / IL-23 p19 ELISA Kit
Select
Sandwich
96-Well Microplate
Mouse
15.625 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$586
IL23A / IL-23 p19 ELISA Kit
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Sandwich
96-Well Microplate
Chicken
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$656
IL23A / IL-23 p19 ELISA Kit
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Sandwich
96-Well Strip Plate
Rat
50 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$805
IL23A / IL-23 p19 ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
100 - 2500 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$805
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).