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IL1RN

interleukin 1 receptor antagonist

IL1RN is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses. This gene and five other closely related cytokine genes form a gene cluster spanning approximately 400 kb on chromosome 2. A polymorphism of this gene is reported to be associated with increased risk of osteoporotic fractures and gastric cancer. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.

Gene Name: interleukin 1 receptor antagonist
Family/Subfamily: IL-1 , not assigned-IL-1
Synonyms: IL1RN, DIRA, IL-1ra, IL-1RN, IL1F3, IL1RA, MVCD4, IL1 inhibitor, IL1RN (IL1F3), IRAP, ICIL-1RA, IL-1ra3
Target Sequences: NM_000577 NP_000568.1 P18510

☰ Filters
Products
Proteins (47)
Over-Expression Lysate (8)
Recombinant (38)
IL1RN (47)
Animal-free (1)
No (47)
Fc (1)
GST (1)
His (9)
His, N-Terminal (3)
His-S (1)
His-T7 (1)
Myc-DDK (Flag) (11)
Bovine (2)
Dog (2)
Horse (2)
Human (27)
Mouse (6)
Pig (1)
Rabbit (1)
Rat (1)
Rhesus monkey (1)
293F Cells (1)
293T Cells (4)
E. coli (29)
HEK 293 Cells (8)
Human Cells (1)
Wheat Germ Extract (1)
Yeast (2)
Purified (12)
Low endotoxin level (13)
Biologically active (9)
Animal-free (1)
IL1RN Protein
Select
E. coli
None
Less than 1.0 EU/µg protein (determined by LAL method).
100 µg/$361; 500 µg/$739; 20 µg/$261
Select
E. coli
None
Biologically active
Less than 0.1 ng/µg of protein (less than 1EU/µg).
17.2 kDa
20 µg/$268; 100 µg/$349
Select
E. coli
None
Biologically active
Less than 0.01 ng/µg of protein (Less than 0.1 EU/µg).
20 µg/$282; 100 µg/$370
IL1RN Protein
Select
E. coli
His
100 µg/$367; 0.5 mg/$769
IL1RN Protein
Select
E. coli
None
Biologically active
17.1 kDa
100 µg/$425; 500 µg/$789
IL1RN Protein
Select
E. coli
None
Biologically active
17.4 kDa
5 µg/$282; 100 µg/$700; 500 µg/$1,408
IL1RN Protein
Select
E. coli
None
Biologically active
17.3 kDa
100 µg/$468; 500 µg/$946
IL1RN Protein - 12.5% SDS-PAGE of human IL1RN stained with Coomassie Blue
Select
Wheat Germ Extract
GST
43.23 kDa
10 µg/$479; 25 µg/$670
Select
None
17 kD
20 µg/$476
Select
E. coli
None
Less than 1.0 EU/µg protein (determined by LAL method).
17.26kD
10 µg/$240; 50 µg/$284; 500 µg/$743; 1 mg/$1,048
Select
E. coli
None
Less than 1.0 EU/µg protein (determined by LAL method).
17.5kD
10 µg/$321; 50 µg/$534; 500 µg/$1,585; 1 mg/$2,157
IL1RN Protein - Purified recombinant protein IL1RN was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
17.1 kDa
20 µg/$1,107
IL1RN Protein - Purified recombinant protein IL1RN was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc-DDK (Flag)
17.7 kDa
20 µg/$1,107
IL1RN Protein - Purified recombinant protein IL1RN was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc-DDK (Flag)
16 kDa
20 µg/$1,107
Select
Human Cells
Fc
Less than 1.0 EU/µg protein (determined by LAL method).
43.8 kDa
50 µg/$556
IL1RN Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
19.7 kDa
100 µg/$494
IL1RN Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
17.7 kDa
20 µg/$150
IL1RN Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
19.7 kDa
20 µg/$150
IL1RN Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
17.1 kDa
20 µg/$150
Select
293T Cells
Myc-DDK (Flag)
16 kDa
20 µg/$150
IL1RN Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
17.1 kDa
100 µg/$494
IL1RN Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
16 kDa
100 µg/$494
Select
E. coli
None
Biologically active
Less than 1 EU/µg (determined by LAL method).
17.258 kDa
10 µg/$296; 1 mg/$1,563; 50 µg/$470
IL1RN Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
17.7 kDa
100 µg/$494
IL1RN Protein - Recombinant Bovine interleukin-1RA detected using Goat anti Bovine interleukin-1RA as the capture reagent and Goat anti Bovine interleukin-1RA:Biotin as the detection reagent followed by Streptavidin:HRP.
Select
Yeast
None
17.2 kDa
5 µg/$390
Viewing 1-25 of 47 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).