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IL1RL1

interleukin 1 receptor-like 1

IL1RL1 is a member of the interleukin 1 receptor family. Studies of the similar gene in mouse suggested that this receptor can be induced by proinflammatory stimuli, and may be involved in the function of helper T cells. This gene, interleukin 1 receptor, type I (IL1R1), interleukin 1 receptor, type II (IL1R2) and interleukin 1 receptor-like 2 (IL1RL2) form a cytokine receptor gene cluster in a region mapped to chromosome 2q12. Alternative splicing of this gene results in multiple transcript variants.

Gene Name: interleukin 1 receptor-like 1
Synonyms: IL1RL1, DER4, Growth stimulation-expressed, IL33R, Interleukin-1 receptor-like 1, Interleukin 1 receptor-like 1, ST2, ST2L, ST2V, FIT-1, Protein ST2, ST2 protein, IL-1R4, IL1R4
Target Sequences: NM_016232 NP_057316.3 Q01638

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Products
Proteins (20)
Over-Expression Lysate (2)
Recombinant (18)
IL1RL1 (20)
No (20)
6His, C-terminus (4)
Fc (1)
Fc, C-terminus (2)
His (4)
His,C-terminus (1)
Human IgG1 Fc (2)
Human IgG1 Fc, N-terminus (1)
Mouse IgG2 Fc (1)
Myc-DDK (Flag) (2)
Human (14)
Mouse (5)
293T Cells (1)
CHO Cells (3)
E. coli (3)
HEK 293 Cells (5)
Human Cells (5)
Mammalian Cells (3)
Purified (5)
Low endotoxin level (16)
Biologically active (4)
Select
Human Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
36kD
10 µg/$248; 50 µg/$288; 500 µg/$785; 1 mg/$1,203
Select
Human Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
36.6kD
10 µg/$281; 50 µg/$395; 500 µg/$1,585; 1 mg/$2,157
Select
Human Cells
Fc, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
62.7kD
10 µg/$281; 50 µg/$395; 500 µg/$1,585; 1 mg/$2,157
IL1RL1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
36.99 kDa
20 µg/$150
Select
Human Cells
His
Less than 1.0 EU/µg protein (determined by LAL method).
36.5 kDa
100 µg/$502
Select
Human Cells
Fc
Less than 1.0 EU/µg protein (determined by LAL method).
67.1 kDa
100 µg/$502
IL1RL1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
36.99 kDa
100 µg/$494
Select
CHO Cells
Human IgG1 Fc, N-terminus
Biologically active
Less than 0.06 EU/µg protein (determined by LAL method).
50 µg/$442
IL1RL1 Protein - Human IL-1R1L1 inhibits the proliferation of D10.G4.1 cells induced by IL-33 in a dose dependent manner.
Select
HEK 293 Cells
None
Biologically active
Less than 0.01 ng/µg (determined by LAL method).
The 550 amino acid recombinant protein has a predicted molecular mass of approximately 62 kD. The DTT-reduced and non-reduced protein migrate approximately at 100 kD and 200 kD by SDS-PAGE. The predicted N-terminal amino acid is Lys.
25 µg/$325; 100 µg/$459
Select
HEK 293 Cells
None
Less than 1.0 EU/µg protein (determined by LAL method).
35.6 kDa
100 µg/$721
Select
Mammalian Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
36.0 kDa
10 µg/$248; 50 µg/$288
Select
Mammalian Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
36.6 kDa
10 µg/$281; 50 µg/$389
Select
Mammalian Cells
Fc, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
62.7 kDa
10 µg/$281; 50 µg/$389
Select
HEK 293 Cells
His,C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
36.3 kDa
100 µg/$721
Select
E. coli
309 AA
His
Less than 0.1 EU/µg protein (determined by LAL method).
34.1 kDa
10 mg/$4,268; 5 mg/$3,201; 1 mg/$1,868; 0.5 mg/$1,475; 200 µg/$1,103; 100 µg/$756; 50 µg/$531
Select
CHO Cells
Human IgG1 Fc
Biologically active
Less than 0.06 EU/µg protein (determined by LAL method).
50 µg/$442
Select
CHO Cells
Mouse IgG2 Fc
Biologically active
Less than 0.06 EU/µg protein (determined by LAL method).
50 µg/$442
Select
E. coli
His
21.7 kDa
10 µg/$281; 50 µg/$442; 100 µg/$705; 200 µg/$882; 1 mg/$1,989; 500 µg/$1,529; 5 mg/$3,081; 2 mg/$2,176
Select
E. coli
His
22.2 kDa
10 µg/$281; 50 µg/$442; 100 µg/$705; 200 µg/$882; 1 mg/$1,989; 500 µg/$1,529; 5 mg/$3,081; 2 mg/$2,176
IL1RL1 Protein - hIL-33 binding to hST2-Fc confirmed by pull down assay. a) pull down of h-IL-33 by hST2-Fc. b) pull down of hST2-Fc by h-IL-33-His. 5 ug of hST2-Fc (or control Fc protein), 2 ug of hIL-33-His (or control His protein), and protein G resin (or anti-His resin) were incubated in 0.5ml RIPA buffer overnight at 4 degrees C. The precipitates were separated by SDS-PAGE, electro-transferred onto NC membrane, and immunoblotted for the presence of hIL-33-His or hST2-Fc with anti-His HRP or anti-hIgG HRP, respectively.
Select
HEK 293 Cells
Human IgG1 Fc
Less than 0.1 EU/µg protein (determined by LAL method).
~90kDa (SDS-PAGE)
50 µg/$505
Viewing 1-20 of 20 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).