IL1F9

interleukin 36, gamma

Cytokine that binds to and signals through the IL1RL2/IL-36R receptor which in turn activates NF-kappa-B and MAPK signaling pathways in target cells. Part of the IL-36 signaling system that is thought to be present in epithelial barriers and to take part in local inflammatory response; similar to the IL-1 system with which it shares the coreceptor IL1RAP. Seems to be involved in skin inflammatory response by acting on keratinocytes, dendritic cells and indirectly on T cells to drive tissue infiltration, cell maturation and cell proliferation. In cultured keratinocytes induces the expression of macrophage, T cell, and neutrophil chemokines, such as CCL3, CCL4, CCL5, CCL2, CCL17, CCL22, CL20, CCL5, CCL2, CCL17, CCL22, CXCL8, CCL20 and CXCL1; also stimulates its own expression and that of the prototypic cutaneous proinflammatory parameters TNF-alpha, S100A7/psoriasin and inducible NOS. May play a role in proinflammatory responses during particular neutrophilic airway inflammation: activates mitogen-activated protein kinases and NF-kappa B in primary lung fibroblasts, and stimulates the expression of IL-8 and CXCL3 and Th17 chemokine CCL20 in lung fibroblasts. May be involved in the innate immune response to fungal pathogens, such as Aspergillus fumigatus.

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Products

Proteins (27)

Type

Over-Expression Lysate (2)

Recombinant (25)

Target

IL1F9 (27)

Format

Animal-free (1)

Publications

No (27)

Tag

DDK (Flag) (1)

GST, N-terminus (2)

His (4)

His, N-Terminal (1)

His-T7 (2)

Myc-DDK (Flag) (3)

Species

Human (20)

Mouse (5)

Rat (1)

Source

293T Cells (1)

E. coli (23)

HEK 293 Cells (2)

Wheat Germ Extract (1)

Purification

Purified (10)

Low Endotoxin Level

Low endotoxin level (10)

Biologically Active

Biologically active (7)

Animal-free

Animal-free (1)

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Human IL1F9 Protein (Recombinant) - LS-G188

Source:

E. coli

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 0.1 ng/µg of protein (less than 1EU/µg).

Molecular Weight:

17.0 kDa

Price:

2 µg/$268; 10 µg/$349

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Human IL1F9 Protein (Recombinant) - LS-G3657

Source:

E. coli

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 0.01 ng/µg of protein (Less than 0.1 EU/µg).

Price:

2 µg/$282; 10 µg/$370

• Unmodified
• Animal-free

• Unmodified
• Animal-free

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Human IL1F9 Protein (Recombinant) (aa18-169) - LS-G5748

Source:

E. coli

Tag:

None

Biological Activity:

Biologically active

Molecular Weight:

17.0 kDa

Price:

10 µg/$388; 100 µg/$1,466; 500 µg/$3,025

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Human IL1F9 Protein (Recombinant) (aa1-169) - LS-G5747

Source:

E. coli

Tag:

None

Biological Activity:

Biologically active

Molecular Weight:

18.7 kDa

Price:

10 µg/$388; 100 µg/$1,466; 500 µg/$3,025

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Mouse IL1F9 Protein (Recombinant) (aa13-164) - LS-G5853

Source:

E. coli

Tag:

None

Biological Activity:

Biologically active

Molecular Weight:

17.3 kDa

Price:

10 µg/$388; 500 µg/$3,629; 100 µg/$1,661

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Human IL1F9 Protein (Recombinant GST, N-terminus) (aa1-110) - LS-G64606

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human IL1F9 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G91159

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

18.5 kDa

Price:

20 µg/$150

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Human IL1F9 Protein (Recombinant) (Met1-Asp169) - LS-G97591

Source:

E. coli

Tag:

None

Molecular Weight:

18.9 kDa

Price:

50 µg/$556

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Human IL1F9 Protein (Recombinant His) (Ser18-Asp169) - LS-G97592

Source:

E. coli

Tag:

His

Molecular Weight:

19.1 kDa

Price:

20 µg/$428

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Human IL1F9 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G72009

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

18.5 kDa

Price:

20 µg/$1,107

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Human IL1F9 Protein (Recombinant) (Ser18-Asp169) - LS-G40218

Source:

E. coli

Tag:

None

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

17kD

Price:

10 µg/$321; 50 µg/$534; 500 µg/$1,680; 1 mg/$2,353

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IL1F9 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G111387

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

18.5 kDa

Price:

100 µg/$494

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Mouse IL1F9 Protein (Recombinant) - LS-G146242

Source:

E. coli

Tag:

None

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

17.3 kDa

Price:

10 µg/$388; 50 µg/$875

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Human IL1F9 Protein (Recombinant) - LS-G131424

Source:

E. coli

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

~18.9 kDa

Price:

10 µg/$291; 100 µg/$559; 1 mg/$2,707

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Human IL1F9 Protein (Recombinant) - LS-G134361

Source:

E. coli

Tag:

None

Endotoxin Level:

Less than 0.01 EU/µg protein (determined by LAL method).

Molecular Weight:

~17 kDa

Price:

10 µg/$344

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Human IL1F9 Protein (Recombinant) (Full Length) - LS-G136696

Source:

E. coli

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

17 kDa

Price:

50 µg/$698; 10 µg/$356; 1 mg/$3,095; 500 µg/$2,167

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Human IL1F9 Protein (Recombinant) (Ser18-Asp169) - LS-G138391

Source:

E. coli

Tag:

None

Molecular Weight:

17 kDa

Price:

20 µg/$428

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Human IL1F9 Protein (Recombinant His, N-Terminal) - LS-G132802

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

19kDa

Price:

10 µg/$348; 50 µg/$862; 200 µg/$1,505; 100 µg/$1,281; 1 mg/$2,817; 500 µg/$2,313; 5 mg/$6,021; 2 mg/$3,212

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Human IL1F9 Protein (Recombinant) (Ser18-Asp169) - LS-G140237

Source:

E. coli

Tag:

None

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

17.0 kDa

Price:

20 µg/$360; 100 µg/$728

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Mouse IL1F9 Protein (Recombinant DDK (Flag)) (aa13-164) - LS-G3938

Source:

E. coli

Tag:

DDK (Flag)

Endotoxin Level:

Less than 0.01 EU/µg protein (determined by LAL method).

Molecular Weight:

~17kDa

Price:

10 µg/$344

Select

Mouse IL1F9 Protein (Recombinant) (aa13-164) - LS-G3937

Source:

E. coli

Tag:

None

Endotoxin Level:

Less than 0.01 EU/µg protein (determined by LAL method).

Molecular Weight:

~17kDa

Price:

10 µg/$344

Select

Human IL1F9 Protein (Recombinant His-T7) (aa1-158) - LS-G25535

Source:

E. coli

Tag:

His-T7

Molecular Weight:

21.3 kDa

Price:

10 µg/$282; 50 µg/$450; 100 µg/$717; 200 µg/$897; 1 mg/$2,010; 500 µg/$1,547; 5 mg/$3,137; 2 mg/$2,198

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Rat IL1F9 Protein (Recombinant His-T7) (aa5-153) - LS-G26123

Source:

E. coli

Tag:

His-T7

Molecular Weight:

20.1 kDa

Price:

10 µg/$277; 50 µg/$420; 100 µg/$670; 200 µg/$837; 1 mg/$1,928; 500 µg/$1,474; 5 mg/$2,927; 2 mg/$2,113

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Human IL1F9 Protein (Recombinant His) (aa1-162) - LS-G16147

Source:

E. coli

Tag:

His

Molecular Weight:

19.4 kDa

Price:

10 µg/$284; 50 µg/$462; 100 µg/$737; 200 µg/$922; 1 mg/$2,042; 500 µg/$1,577; 5 mg/$3,221; 2 mg/$2,231

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Mouse IL1F9 Protein (Recombinant His) (aa5-149) - LS-G16150

Source:

E. coli

Tag:

His

Molecular Weight:

17.7 kDa

Price:

10 µg/$287; 50 µg/$482; 100 µg/$770; 200 µg/$962; 1 mg/$2,094; 500 µg/$1,623; 5 mg/$3,361; 2 mg/$2,284

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