IL1F9

interleukin 36, gamma

Cytokine that binds to and signals through the IL1RL2/IL-36R receptor which in turn activates NF-kappa-B and MAPK signaling pathways in target cells. Part of the IL-36 signaling system that is thought to be present in epithelial barriers and to take part in local inflammatory response; similar to the IL-1 system with which it shares the coreceptor IL1RAP. Seems to be involved in skin inflammatory response by acting on keratinocytes, dendritic cells and indirectly on T cells to drive tissue infiltration, cell maturation and cell proliferation. In cultured keratinocytes induces the expression of macrophage, T cell, and neutrophil chemokines, such as CCL3, CCL4, CCL5, CCL2, CCL17, CCL22, CL20, CCL5, CCL2, CCL17, CCL22, CXCL8, CCL20 and CXCL1; also stimulates its own expression and that of the prototypic cutaneous proinflammatory parameters TNF-alpha, S100A7/psoriasin and inducible NOS. May play a role in proinflammatory responses during particular neutrophilic airway inflammation: activates mitogen-activated protein kinases and NF-kappa B in primary lung fibroblasts, and stimulates the expression of IL-8 and CXCL3 and Th17 chemokine CCL20 in lung fibroblasts. May be involved in the innate immune response to fungal pathogens, such as Aspergillus fumigatus.

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Products

Antibodies (65)

Proteins (27)

ELISA Kits (8)

Type

Over-Expression Lysate (2)

Primary (65)

Recombinant (25)

Sandwich (6)

Sandwich CLIA (2)

Target

IL1F9 (100)

Reactivity

Human (42)

Mouse (26)

Rat (10)

Application

IHC (12)

IHC-P (7)

WB (48)

ELISA (15)

IF (3)

IP (1)

Peptide-ELISA (1)

Host

rabbit (50)

mouse (8)

rat (7)

Product Group

IHCPlus (2)

Isotype

IgG (17)

IgG1 (3)

IgG1,k (2)

IgG2b (2)

Clonality

monoclonal mc (15)

polyclonal pc (50)

Clone

10 (1)

2A8 (1)

2F4 (2)

Jussy-1 (1)

OTI6E4 (2)

Format

96-Well Microplate (1)

96-Well Strip Plate (7)

Animal-free (1)

APC (5)

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Biotin Conjugated (6)

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Epitope

aa5-149 (16)

aa1-158 (8)

aa1-162 (8)

aa5-153 (8)

aa105-169 (1)

Publications

No (97)

Yes (3)

Sample Type

Cell Culture Supernatants (4)

Cell Lysates (3)

Plasma (8)

Serum (8)

Tissue Homogenates (4)

Tag

DDK (Flag) (1)

GST, N-terminus (2)

His (4)

His, N-Terminal (1)

His-T7 (2)

Myc-DDK (Flag) (3)

Species

Human (20)

Mouse (5)

Rat (1)

Source

293T Cells (1)

E. coli (23)

HEK 293 Cells (2)

Wheat Germ Extract (1)

Purification

Purified (10)

Low Endotoxin Level

Low endotoxin level (10)

Biologically Active

Biologically active (7)

Animal-free

Animal-free (1)

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IL1F9 Antibody (aa5-149) LS-C294790

(4.0) Rating

(1) Publication(s)

Antibody:

IL1F9 Rabbit anti-Mouse Polyclonal (aa5-149) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$321; 200 µl/$369; 500 µl/$527; 1 ml/$611; 2 ml/$842; 5 ml/$1,387

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IL1F9 Antibody (aa5-149, Biotin) LS-C689395

Antibody:

IL1F9 Rabbit anti-Mouse Polyclonal (aa5-149) (Biotin) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$333; 200 µl/$385; 500 µl/$559; 1 ml/$671; 2 ml/$907; 5 ml/$1,525

• Unconjugated
• Biotin

• Unconjugated
• Biotin

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IL1F9 Antibody (aa5-149) LS-C314326

(4.0) Rating

(1) Publication(s)

Antibody:

IL1F9 Mouse anti-Mouse Monoclonal (aa5-149) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$327; 200 µl/$377; 500 µl/$543; 1 ml/$642; 2 ml/$876; 5 ml/$1,457

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IL1F9 Antibody (aa5-149, Biotin) LS-C689397

Antibody:

IL1F9 Rat anti-Mouse Monoclonal (aa5-149) (Biotin) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$339; 200 µl/$394; 500 µl/$577; 1 ml/$705; 2 ml/$942; 5 ml/$1,603

• Unconjugated
• Biotin

• Unconjugated
• Biotin

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IL1F9 Antibody (clone OTI6E4) LS-C174631

Antibody:

IL1F9 Mouse anti-Human Monoclonal (OTI6E4) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$434

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IL1F9 Antibody (clone OTI6E4, Carrier-free) LS-C787963

Antibody:

IL1F9 Mouse anti-Human Monoclonal (Carrier-free) (OTI6E4) Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

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IL1F9 Antibody LS-C409839

Antibody:

IL1F9 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

20 µl/$275; 100 µl/$389

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IL1F9 Antibody LS-C201142

(4.0) Rating

(1) Publication(s)

Antibody:

IL1F9 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, WB

Format:

Unconjugated

Price:

0.1 mg/$460

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IHC-plus™ IL1F9 Antibody (clone 2F4) LS-B13566

(4.0) Rating

Antibody:

IL1F9 Mouse anti-Human Monoclonal (2F4) Antibody

Reactivity:

Human

Applications:

IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$460

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IL1F9 Antibody (aa105-169) LS-C185990

Antibody:

IL1F9 Rabbit anti-Human Polyclonal (aa105-169) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$450

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Human IL1F9 (Sandwich ELISA) ELISA Kit - LS-F3354

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

12.29 - 3000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum

Price:

1 Plate/$534

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Mouse IL1F9 (Sandwich ELISA) ELISA Kit - LS-F7319

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

7.81 - 500 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$811

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IHC-plus™ IL1F9 Antibody (clone 2A8) LS-B15618

(4.0) Rating

Antibody:

IL1F9 Mouse anti-Human Monoclonal (2A8) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$460

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IL1F9 Antibody LS-C802375

Antibody:

IL1F9 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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IL1F9 Antibody LS-C496876

Antibody:

IL1F9 Rabbit anti-Mouse Polyclonal Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Unconjugated

Price:

20 µl/$275; 100 µl/$389

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Human IL1F9 (Sandwich ELISA) ELISA Kit - LS-F6845

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

15.6 - 1000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$792

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IL1F9 Antibody LS-C487610

Antibody:

IL1F9 Rabbit anti-Mouse Polyclonal Antibody

Reactivity:

Mouse

Applications:

ELISA

Format:

Unconjugated

Price:

20 µl/$271; 100 µl/$412

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IL1F9 Antibody LS-C487612

Antibody:

IL1F9 Rabbit anti-Mouse Polyclonal Antibody

Reactivity:

Mouse

Applications:

ELISA

Format:

Unconjugated

Price:

100 µl/$412

Select

IL1F9 Antibody LS-C487613

Antibody:

IL1F9 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA

Format:

Unconjugated

Price:

100 µl/$375; 200 µl/$473; 400 µl/$648

Select

IL1F9 Antibody (clone 2F4, Carrier-free) LS-C787964

Antibody:

IL1F9 Mouse anti-Human Monoclonal (Carrier-free) (2F4) Antibody

Reactivity:

Human

Applications:

IF, IHC, WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

Select

Human IL1F9 (Sandwich ELISA) ELISA Kit - LS-F11793

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

31.2 - 2000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$585

Select

Mouse IL1F9 (Sandwich ELISA) ELISA Kit - LS-F19488

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

15.6 - 1000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$585

Select

Mouse IL1F9 (CLIA) ELISA Kit - LS-F26296

Type:

Sandwich CLIA

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

1.37 - 1000 pg/ml

Detection:

Chemiluminescent

Sample Types:

Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$871

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IL1F9 Antibody LS-C751715

Antibody:

IL1F9 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$351

Select

IL1F9 Antibody LS-C487611

Antibody:

IL1F9 Rabbit anti-Mouse Polyclonal Antibody

Reactivity:

Mouse

Applications:

ELISA, IP, WB

Format:

Unconjugated

Price:

100 µl/$412

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