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Cytokine with immunomodulatory activity. Alone, does not induce cytokine production, but reduces IL22 and IL17A production by T-cells in response to heat-killed Candida albicans. Reduces IL36G-induced production of IL8 by peripheral blood mononuclear cells. Increases IL6 production by dendritic cells stimulated by bacterial lipopolysaccharides (LPS). Ligand for IL-36R/IL1RL2.
Gene Name: | interleukin 1 family, member 10 (theta) |
Family/Subfamily: | IL-1 , not assigned-IL-1 |
Synonyms: | IL1F10, IL-1 theta, IL-1HY2, IL1-theta, IL-38, Interleukin-1 HY2, FIL1 theta, FIL1T, FKSG75, IL1HY2, Interleukin-1 theta, FIL1-theta, IL-1F10, Interleukin-1 family member 10 |
Target Sequences: | NM_032556 NP_115945.4 Q8WWZ1 |
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