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Feedback inhibitor of fibroblast growth factor mediated Ras-MAPK signaling and ERK activation. May inhibit FGF-induced FGFR1 tyrosine phosphorylation. Regulates the nuclear ERK signaling pathway by spatially blocking nuclear translocation of activated ERK without inhibiting cytoplasmic phosphorylation of ERK. Mediates JNK activation and may be involved in apoptosis. Might have a role in the early stages of fate specification of GnRH-secreting neurons.
Gene Name: | interleukin 17 receptor D |
Synonyms: | IL17RD, HSef, IL-17 receptor D, IL17RLM, Interleukin 17 receptor D, IL17Rhom, Interleukin-17 receptor D, SEF, Sef homolog, IL-17RD |
Target Sequences: | AL133097 Q8NFM7 Q8NFM7 |
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