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IL17RB

interleukin 17 receptor B

IL17RB is a type I transmembrane protein with 17% homology to IL17R. Studies have shown that IL17RB binds strongly to IL17E, weakly to IL17B but does not bind IL17 or IL17C. The IL17 proteins are a family of potent cytokines that act to induce proinflammatory responses. Receptor binding of ligand has been shown to lead to the activation of nuclear factor kappa-B and production of IL8. Studies in a rat model of chemically induced IBD showed increased expression of IL17RB in the small intestine of treated rats.

Gene Name: interleukin 17 receptor B
Family/Subfamily: Interleukin
Synonyms: IL17RB, CRL4, Cytokine receptor-like 4, EVI27, IL-17 receptor B, IL-17 receptor homolog 1, IL-17B receptor, IL-17RB, Interleukin 17 receptor B, IL17RH1, IL17BR, Interleukin 17B receptor, Interleukin-17B receptor, Cytokine receptor CRL4, IL-17Rh1, Interleukin-17 receptor B, IL25R, IL-25R
Target Sequences: NM_018725 NP_061195.2 Q9NRM6

Publications (1)

1
Interleukin-25 and mucosal T cells in noneosinophilic and eosinophilic chronic rhinosinusitis. Tomohisa Iinuma, Yoshitaka Okamoto, Heizaburo Yamamoto, Ayako Inamine-Sasaki, Yuji Ohki, Toshioki Sakurai, Urara Funakoshi, Syuji Yonekura, Daiju Sakurai, Kiyoshi Hirahara, Toshinori Nakayama. The Breast : official journal of the European Society of Mastology. 2015 Apr;;114:289-98. [Full Text Article] [PubMed:25704964]

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Proteins (8)
Recombinant (8)
IL17RB (8)
No (8)
Fc, C-terminus (1)
GST, N-terminus (1)
His (4)
His, N-Terminal (1)
His-T7 (1)
Human (5)
Mouse (2)
Rat (1)
E. coli (4)
HEK 293 Cells (1)
Human Cells (2)
Wheat Germ Extract (1)
Purified (3)
Low endotoxin level (3)
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Human Cells
His
Less than 1.0 EU/µg protein (determined by LAL method).
31.3 kDa
100 µg/$721
IL17RB Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
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HEK 293 Cells
Fc, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
56.9 kDa
100 µg/$721
IL17RB Protein - Active Interleukin 17 Receptor B (IL17RB) by WB
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E. coli
His, N-Terminal
19kDa
10 µg/$283; 50 µg/$452; 200 µg/$902; 100 µg/$722; 1 mg/$2,016; 500 µg/$1,553; 5 mg/$3,151; 2 mg/$2,204
IL17RB Protein - Recombinant  Interleukin 17 Receptor B By SDS-PAGE
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E. coli
His-T7
19.5 kDa
10 µg/$279; 50 µg/$432; 100 µg/$690; 200 µg/$862; 1 mg/$1,962; 500 µg/$1,505; 5 mg/$3,011; 2 mg/$2,148
IL17RB Protein - Recombinant Interleukin 17 Receptor B By SDS-PAGE
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E. coli
His
22.4 kDa
10 µg/$285; 50 µg/$465; 100 µg/$742; 200 µg/$930; 1 mg/$2,052; 500 µg/$1,586; 5 mg/$3,249; 2 mg/$2,241
IL17RB Protein - Recombinant Interleukin 17 Receptor B By SDS-PAGE
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E. coli
His
23.0 kDa
10 µg/$282; 50 µg/$447; 100 µg/$715; 200 µg/$892; 1 mg/$2,005; 500 µg/$1,543; 5 mg/$3,123; 2 mg/$2,192
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Human Cells
His
Less than 1.0 EU/µg protein (determined by LAL method).
31.5 kDa
100 µg/$721
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).