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Newark, CA 94560
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IL17RB
interleukin 17 receptor B
IL17RB is a type I transmembrane protein with 17% homology to IL17R. Studies have shown that IL17RB binds strongly to IL17E, weakly to IL17B but does not bind IL17 or IL17C. The IL17 proteins are a family of potent cytokines that act to induce proinflammatory responses. Receptor binding of ligand has been shown to lead to the activation of nuclear factor kappa-B and production of IL8. Studies in a rat model of chemically induced IBD showed increased expression of IL17RB in the small intestine of treated rats.
| Gene Name: | interleukin 17 receptor B |
| Family/Subfamily: | Interleukin |
| Synonyms: | IL17RB, CRL4, Cytokine receptor-like 4, EVI27, IL-17 receptor B, IL-17 receptor homolog 1, IL-17B receptor, IL-17RB, Interleukin 17 receptor B, IL17RH1, IL17BR, Interleukin 17B receptor, Interleukin-17B receptor, Cytokine receptor CRL4, IL-17Rh1, Interleukin-17 receptor B, IL25R, IL-25R |
| Target Sequences: | NM_018725 NP_061195.2 Q9NRM6 |
Publications (1)
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