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Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
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IL16

interleukin 16

Interleukin-16 stimulates a migratory response in CD4+ lymphocytes, monocytes, and eosinophils. Primes CD4+ T-cells for IL-2 and IL-15 responsiveness. Also induces T-lymphocyte expression of interleukin 2 receptor. Ligand for CD4.Isoform 1 may act as a scaffolding protein that anchors ion channels in the membrane.Isoform 3 is involved in cell cycle progression in T-cells. Appears to be involved in transcriptional regulation of SKP2 and is probably part of a transcriptional repression complex on the core promoter of the SKP2 gene. May act as a scaffold for GABPB1 (the DNA-binding subunit the GABP transcription factor complex) and HDAC3 thus maintaining transcriptional repression and blocking cell cycle progression in resting T-cells.

Gene Name: interleukin 16
Family/Subfamily: Hormone , not assigned-Hormone
Synonyms: IL16, IL-16, Interleukin 16, Neuronal interleukin 16, PrIL-16, NIL16, HsT19289, LCF, PRIL16, Pro-interleukin-16, Prointerleukin 16
Target Sequences: NM_004513 NP_004504.3 Q14005

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Products
Antibodies (97)
Primary (97)
IL16 (97)
Human (67)
Mouse (20)
Rat (10)
Bovine (8)
Chimpanzee (6)
Cow (8)
Gibbon (6)
Guinea pig (3)
Monkey (4)
Orangutan (3)
IHC (10)
IHC-P (7)
WB (72)
ELISA (38)
Func (2)
ICC (3)
IF (9)
IP (1)
Neut (5)
Peptide-ELISA (2)
rabbit (85)
mouse (12)
Product Group
IHCPlus (1)
IgG (32)
IgG1 (5)
IgG1,k (1)
IgG2a,k (2)
IgG2b,k (1)
IgG3,k (1)
monoclonal mc (14)
polyclonal pc (83)
005 (1)
022 (1)
228 (1)
55 (1)
G11/II (1)
GF1 (1)
APC (4)
APC Conjugated (5)
Biotin Conjugated (10)
Cy3 Conjugated (4)
Cy7 Conjugated (4)
FITC Conjugated (9)
HRP Conjugated (9)
PE Conjugated (6)
Preservative Free (5)
Unconjugated (50)
aa1203-1322 (8)
aa1203-1332 (8)
aa1204-1323 (8)
aa508-627 (8)
C-Terminus (4)
aa76-125 (4)
C-terminal (1)
Gly97 (1)
N-Terminus (1)
aa1204-1332 (1)
aa1212-1332 (1)
aa1268-1332 (1)
aa1283-1332 (1)
aa48-97 (1)
No (97)
IL16 Antibody - Anti-IL-16 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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IL16 Mouse Monoclonal (G11/II) Antibody
Human
IHC, IHC-P
Unconjugated
50 µg/$525
IL16 Antibody - Immunohistochemistry of IL-16 in mouse brain tissue with IL-16 antibody at 2.5 µg/mL.
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IL16 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
0.1 mg/$460
IL16 Antibody - Western blot of recombinant IL16.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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IL16 Rabbit anti-Mouse Polyclonal (aa1203-1322) (Biotin) Antibody
Mouse
WB
Biotin Conjugated
100 µl/$311; 200 µl/$353; 500 µl/$496; 1 ml/$567; 2 ml/$769; 5 ml/$1,248
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IL16 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, Func, Neut, WB
Unconjugated
100 µg/$732
IL16 Antibody - Western Blot (non-reducing) of IL-16 antibody. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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IL16 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
50 µg/$356; 100 µg/$396
IL16 Antibody - Western Blot (non-reducing) of IL-16 antibody. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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IL16 Rabbit anti-Human Polyclonal (aa1204-1332) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
25 µg/$356; 50 µg/$396
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IL16 Rabbit anti-Mouse Monoclonal (Preservative Free) (005) Antibody
Mouse
ELISA
Unconjugated, Preservative Free
20 µl/$271; 100 µl/$412
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IL16 Rabbit anti-Mouse Monoclonal (Preservative Free) (022) Antibody
Mouse
ELISA
Unconjugated, Preservative Free
20 µl/$271; 100 µl/$412
IL16 Antibody - Immunohistochemistry of IL-16 in mouse brain tissue with IL-16 antibody at 2.5 µg/mL.
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IL16 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
0.1 mg/$460
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IL16 Rabbit anti-Human Monoclonal (Preservative Free) (228) Antibody
Human
ELISA
Unconjugated, Preservative Free
20 µl/$271; 100 µl/$412
IL16 Antibody - IL16 antibody IHC-paraffin: Human Tonsil Tissue.
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IL16 Rabbit anti-Human Polyclonal (aa1212-1332) Antibody
Human
ICC, IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
IL16 Antibody - Immunofluorescence analysis of U2OS cells using IL16 antibody. Blue: DAPI for nuclear staining.
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IL16 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
IL16 Antibody - IHC analysis of IL-16 using anti-IL-16 antibody. IL-16 was detected in paraffin-embedded section of mouse brain tissues. Heat mediated antigen retrieval was performed in citrate buffer (pH6, epitope retrieval solution) for 20 mins. The tissue section was blocked with 10% goat serum. The tissue section was then incubated with 1µg/ml rabbit anti-IL-16 Antibody overnight at 4°C. Biotinylated goat anti-rabbit IgG was used as secondary antibody and incubated for 30 minutes at 37°C. The tissue section was developed using Strepavidin-Biotin-Complex (SABC) with DAB as the chromogen.
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IL16 Rabbit anti-Mouse Polyclonal Antibody
Mouse
ELISA, WB
Unconjugated
10 µg/$318; 100 µg/$470
IL16 Antibody - Immunohistochemical analysis of IL-16 staining in human lymph node formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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IL16 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human, Monkey
IHC, IHC-P, WB
Unconjugated
100 µl/$321
IL16 Antibody - 1:100 staining mouse liver tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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IL16 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
IL16 Antibody - Immunofluorescent analysis of Hela cells using IL16 Antibody at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
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IL16 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF
Unconjugated
50 µg/$294; 100 µg/$360
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IL16 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, Func, WB
Unconjugated
100 µg/$797
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IL16 Mouse anti-Human Monoclonal Antibody
Human
ELISA, WB
Unconjugated
500 µg/$702
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IL16 Mouse anti-Human Monoclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$361
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IL16 Rabbit anti-Human Polyclonal Antibody
Human
ICC, WB
Unconjugated
100 µg/$749
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IL16 Mouse anti-Human Monoclonal Antibody
Human
ELISA, WB
Unconjugated
50 µg/$332; 100 µg/$404; 200 µg/$505
IL16 Antibody - Immunofluorescence analysis of U2OS cells using IL16 Polyclonal Antibody.
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IL16 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
IL16 Antibody - Immunofluorescence of methanol-fixed A549 using IL16 antibody at 1:500 dilution.
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IL16 Rabbit anti-Human Polyclonal (aa1268-1332) Antibody
Human
ICC, WB
Unconjugated
100 µl/$450
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IL16 Rabbit anti-Human Polyclonal Antibody
Human
IHC, IHC-P
Unconjugated
100 µl/$412
IL16 Antibody - Immunohistochemistry analysis of IL-16 antibody in paraffin-embedded human lung carcinoma tissue.
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IL16 Rabbit anti-Human Polyclonal (aa48-97) Antibody
Human
IHC, Peptide-ELISA
Unconjugated
50 µl/$334; 100 µl/$397
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).