IL15

interleukin 15

IL15 is a cytokine that regulates T and natural killer cell activation and proliferation. This cytokine and interleukine 2 share many biological activities. They are found to bind common hematopoietin receptor subunits, and may compete for the same receptor, and thus negatively regulate each other's activity. The number of CD8+ memory cells is shown to be controlled by a balance between this cytokine and IL2. This cytokine induces the activation of JAK kinases, as well as the phosphorylation and activation of transcription activators STAT3, STAT5, and STAT6. Studies of the mouse counterpart suggested that this cytokine may increase the expression of apoptosis inhibitor BCL2L1/BCL-x(L), possibly through the transcription activation activity of STAT6, and thus prevent apoptosis. Alternatively spliced transcript variants of this gene have been reported.

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Products

Proteins (37)

Type

Over-Expression Lysate (2)

Recombinant (35)

Target

IL15 (37)

Format

Animal-free (1)

Publications

No (37)

Tag

6His, N-terminus (1)

GST (2)

GST, N-terminus (1)

His (9)

His, N-Terminal (1)

His-S (1)

Human IgG1 Fc (1)

Mouse IgG2 Fc (1)

Myc-DDK (Flag) (3)

Species

Bovine (2)

Guinea pig (1)

Human (21)

Mouse (5)

Rabbit (1)

Rat (2)

Rhesus monkey (1)

Sheep (1)

Source

293T Cells (1)

CHO Cells (2)

E. coli (25)

HEK 293 Cells (2)

Wheat Germ Extract (3)

Yeast (2)

Purification

Purified (14)

Low Endotoxin Level

Low endotoxin level (17)

Biologically Active

Biologically active (14)

Animal-free

Animal-free (1)

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Rhesus monkey IL15 Protein (Recombinant 6His, N-terminus) (aa49-162) - LS-G22977

Source:

Yeast

Tag:

6His, N-terminus

Molecular Weight:

14.9 kD

Price:

100 µg/$679; 20 µg/$429; 1 mg/$1,973

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Human IL15 Protein (Recombinant) - LS-G172

Source:

E. coli

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 0.1 ng/µg of protein (less than 1EU/µg).

Molecular Weight:

12.9 kDa

Price:

2 µg/$268; 10 µg/$349

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Human IL15 Protein (Recombinant) - LS-G3644

Source:

E. coli

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 0.01 ng/µg of protein (Less than 0.1 EU/µg).

Price:

2 µg/$281; 10 µg/$369

• Unmodified
• Animal-free

• Unmodified
• Animal-free

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Rabbit IL15 Protein (Recombinant His) (aa49-162) - LS-G11419

Source:

E. coli

Tag:

His

Molecular Weight:

14.6 kDa

Price:

10 µg/$287; 50 µg/$482; 100 µg/$770; 200 µg/$962; 1 mg/$2,094; 500 µg/$1,623; 5 mg/$3,361; 2 mg/$2,284

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Rat IL15 Protein (Recombinant) - LS-G412

Source:

E. coli

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 0.1 ng/µg of protein (less than 1EU/µg).

Molecular Weight:

13.5 kDa

Price:

2 µg/$268; 10 µg/$349

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Mouse IL15 Protein (Recombinant) - LS-G193

Source:

E. coli

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 0.1 ng/µg of protein (less than 1EU/µg).

Molecular Weight:

13.3 kDa

Price:

2 µg/$268; 10 µg/$349

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Human IL15 Protein (Recombinant) (aa49-162) - LS-G5710

Source:

E. coli

Tag:

None

Biological Activity:

Biologically active

Molecular Weight:

12.9 kDa

Price:

10 µg/$388; 100 µg/$1,186; 500 µg/$2,269

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Human IL15 Protein (Recombinant GST) (Full Length) - LS-G29050

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

44.5 kDa

Price:

10 µg/$479; 25 µg/$670

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Human IL15 Protein (Recombinant GST) (Full Length) - LS-G29049

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

43.56 kDa

Price:

10 µg/$479; 25 µg/$670

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Human IL15 Protein (Recombinant) - LS-G37716

Tag:

None

Biological Activity:

Biologically active

Molecular Weight:

12.9 kDa

Price:

10 µg/$476

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Mouse IL15 Protein (Recombinant) - LS-G37830

Tag:

None

Biological Activity:

Biologically active

Molecular Weight:

13.3 kDa

Price:

10 µg/$476

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Human IL15 Protein (Recombinant GST, N-terminus) (aa30-129) - LS-G58987

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human IL15 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G66099

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

14.7 kDa

Price:

20 µg/$1,107

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Human IL15 Protein (Recombinant) (Asn49-Ser162) - LS-G38568

Source:

E. coli

Tag:

None

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

12.5kD

Price:

10 µg/$321; 50 µg/$534; 500 µg/$1,353; 1 mg/$1,725

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Human IL15 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G76908

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

14.7 kDa

Price:

20 µg/$150

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IL15 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G102415

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

14.7 kDa

Price:

100 µg/$494

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Mouse IL15 Protein (Recombinant His) (aa49-162) - LS-G141072

Source:

E. coli

Sequence Length:

113 AA

Tag:

His

Endotoxin Level:

Less than 0.1 EU/µg protein (determined by LAL method).

Molecular Weight:

12.54 kDa

Price:

10 mg/$4,268; 5 mg/$3,201; 1 mg/$1,868; 0.5 mg/$1,475; 200 µg/$1,103; 100 µg/$756; 50 µg/$531

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Human IL15 Protein (Recombinant) - LS-G145599

Source:

E. coli

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 1 EU/µg (determined by LAL method).

Molecular Weight:

12.5 kDa

Price:

10 µg/$364; 1 mg/$3,412; 50 µg/$893

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Human IL15 Protein (Recombinant His) - LS-G134296

Source:

E. coli

Tag:

His

Biological Activity:

Biologically active

Endotoxin Level:

Less than 0.1 EU/µg protein (determined by LAL method).

Molecular Weight:

~14 kDa (SDS-PAGE)

Price:

10 µg/$319; 50 µg/$519

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Bovine IL15 Protein (Recombinant) (aa49-162) - LS-G136190

Source:

Yeast

Tag:

None

Molecular Weight:

13.2 kDa

Price:

5 µg/$390

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Human IL15 Protein (Recombinant) - LS-G137482

Source:

E. coli

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 0.01 ng/µg (Less than 0.1 EU/µg) (determined by LAL method).

Molecular Weight:

The 114 amino acid recombinant protein has a predicted molecular mass of 12,773 Da. The DTT-reduced protein migrates at approximately 9kDa and the non-reduced protein migrates at approximately 7kDa by SDS-PAGE. The N-terminal amino acid is Asn.

Price:

10 µg/$359; 25 µg/$436; 100 µg/$951; 500 µg/$2,133

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Mouse IL15 Protein (Recombinant) - LS-G137647

Source:

E. coli

Tag:

None

Endotoxin Level:

Less than 1 EU/µg (determined by LAL method).

Molecular Weight:

The 115 amino acid N-terminal methionylated recombinant protein has a predicted molecular mass of 13,382 Da.

Price:

2 µg/$268; 10 µg/$352; 100 µg/$969

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Human IL15 Protein (Recombinant) (Full Length) - LS-G137395

Source:

E. coli

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

12.5 kDa

Price:

50 µg/$698; 10 µg/$356; 1 mg/$2,269; 500 µg/$1,639

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Human IL15 Protein (Recombinant) - LS-G131258

Source:

E. coli

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

~13 kDa

Price:

10 µg/$357; 1 mg/$6,427

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Human IL15 Protein (Recombinant His, N-Terminal) (aa50-162) - LS-G132808

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

14/16/18kDa

Price:

10 µg/$402; 50 µg/$1,002; 200 µg/$1,668; 100 µg/$1,430; 1 mg/$3,201; 500 µg/$2,501; 5 mg/$7,001; 2 mg/$3,735

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