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IL13

interleukin 13

IL13 is an immunoregulatory cytokine produced primarily by activated Th2 cells. This cytokine is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils. This gene, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL4.

Gene Name: interleukin 13
Family/Subfamily: Hormone , not assigned-Hormone
Synonyms: IL13, ALRH, BHR1, Interleukin-13, NC30, p600, IL-13, Interleukin 13
Target Sequences: NM_002188 NP_002179.2 P35225

Publications (1)

1
A new heterotopic transplant animal model of intestinal fibrosis. Martin Hausmann, Thomas Rechsteiner, Michaela Caj, Christian Benden, Michael Fried, Annette Boehler, Gerhard Rogler. The Breast : official journal of the European Society of Mastology. 2013 Oct;;19:2302-14. [Full Text Article] [PubMed:24013360] Related Antibodies: LS-B3767.

☰ Filters
Products
Proteins (47)
Over-Expression Lysate (2)
Recombinant (45)
IL13 (47)
Animal-free (1)
No (47)
6His, C-terminus (9)
AVI-6His, C-terminus (1)
Fc (1)
Fc, C-terminus (1)
GST (1)
GST, N-terminus (1)
His, C-Terminal (1)
His, N-Terminal (1)
His-S (3)
His-T7 (1)
Mouse IgG Fc, C-terminus (1)
Myc-DDK (Flag) (2)
Bovine (2)
Dog (1)
Human (20)
Mouse (17)
Pig (1)
Rat (4)
Rhesus monkey (1)
293T Cells (1)
CHO Cells (2)
E. coli (26)
HEK 293 Cells (2)
Human (3)
Human Cells (3)
Mammalian Cells (6)
Wheat Germ Extract (2)
Yeast (2)
Purified (15)
Low endotoxin level (32)
Biologically active (22)
Animal-free (1)
IL13 Protein - Recombinant Interleukin 13 (IL13) by SDS-PAGE
Select
E. coli
His, N-Terminal
15.8kDa
10 µg/$286; 50 µg/$472; 200 µg/$942; 100 µg/$752; 1 mg/$2,069; 500 µg/$1,600; 5 mg/$3,291; 2 mg/$2,257
Select
Human Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
14.3kD
10 µg/$321; 50 µg/$534; 500 µg/$1,585; 1 mg/$2,353
IL13 Protein - Recombinant mouse IL-13 induces the proliferation of TF-1 cell in a dose-dependent manner. The ED50 for this effect is 0.3 - 1.5 ng/mL.
Select
E. coli
None
Biologically active
Less than 0.01 ng/µg (Less than 0.1 EU/µg) (determined by LAL method).
The 106 amino acid recombinant protein has a predicted molecular mass of 11,677 Da. The DTT-reduced protein migrates at approximately 9kDa and the non-reduced protein migrates at approximately 8kDa by SDS-PAGE. The N-terminal amino acid is Serine.
10 µg/$344; 25 µg/$478; 100 µg/$1,214; 500 µg/$2,539
IL13 Protein - Recombinant Interleukin 13 By SDS-PAGE
Select
E. coli
His-S
72.6 kDa
10 µg/$299; 50 µg/$552; 100 µg/$882; 200 µg/$1,080; 1 mg/$2,261; 500 µg/$1,775; 5 mg/$3,851; 2 mg/$2,453
Select
E. coli
None
Less than 1.0 EU/µg protein (determined by LAL method).
11.7kD
10 µg/$321; 50 µg/$534; 500 µg/$1,869; 1 mg/$2,991
Select
E. coli
None
Biologically active
Less than 0.1 ng/µg of protein (less than 1EU/µg).
11.9 kDa
2 µg/$268; 10 µg/$349
Select
E. coli
None
Biologically active
Less than 0.1 ng/µg of protein (less than 1EU/µg).
12.3 kDa
2 µg/$268; 10 µg/$349
Select
E. coli
None
Biologically active
Less than 0.1 ng/µg of protein (less than 1EU/µg).
2 µg/$268; 10 µg/$349
Select
E. coli
None
Biologically active
Less than 0.1 ng/µg of protein (less than 1EU/µg).
12.6 kDa
2 µg/$268; 10 µg/$349
Select
E. coli
None
Biologically active
Less than 0.01 ng/µg of protein (Less than 0.1 EU/µg).
2 µg/$281; 10 µg/$369
Select
E. coli
None
Biologically active
Less than 0.1 ng/µg of protein (less than 1EU/µg).
12.3 kDa
2 µg/$268; 10 µg/$349
IL13 Protein
Select
E. coli
None
Biologically active
12.3 kDa
10 µg/$388; 100 µg/$1,466; 500 µg/$3,025
IL13 Protein
Select
E. coli
None
Biologically active
12.5 kDa
10 µg/$388; 100 µg/$1,466; 500 µg/$3,025
IL13 Protein
Select
E. coli
None
Biologically active
12.6 kDa
10 µg/$388; 100 µg/$1,661; 500 µg/$3,629
IL13 Protein
Select
E. coli
None
Biologically active
12.3 kDa
10 µg/$388; 100 µg/$1,466; 500 µg/$3,025
IL13 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
Select
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
IL13 Protein - Recombinant Interleukin 13 By SDS-PAGE
Select
E. coli
His-T7
17.1 kDa
10 µg/$281; 50 µg/$442; 100 µg/$705; 200 µg/$882; 1 mg/$1,989; 500 µg/$1,529; 5 mg/$3,081; 2 mg/$2,176
IL13 Protein - Recombinant  Interleukin 13 By SDS-PAGE
Select
E. coli
His-S
16.1 kDa
10 µg/$289; 50 µg/$492; 100 µg/$785; 200 µg/$982; 1 mg/$2,119; 500 µg/$1,646; 5 mg/$3,921
IL13 Protein - Recombinant  Interleukin 13 By SDS-PAGE
Select
E. coli
His-S
15.8 kDa
10 µg/$287; 50 µg/$482; 100 µg/$770; 200 µg/$962; 1 mg/$2,094; 500 µg/$1,623; 5 mg/$3,361; 2 mg/$2,284
IL13 Protein - 12.5% SDS-PAGE of human IL13 stained with Coomassie Blue
Select
Wheat Germ Extract
GST
40.15 kDa
2 µg/$439
IL13 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
15.79 kDa
20 µg/$150
IL13 Protein - Recombinant Human Interleukin-13/IL-13 (C-Fc)
Select
Human
Fc, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
39.2 kDa
10 µg/$356; 50 µg/$716
IL13 Protein - Recombinant Human Interleukin-13/IL-13 (C-mFc)
Select
Human
Mouse IgG Fc, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
38.7 kDa
10 µg/$349; 50 µg/$682
IL13 Protein - Recombinant Human Interleukin-13/IL-13 (C-Avi-6His) Biotinylated
Select
Human
AVI-6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
15.2 kDa
20 µg/$416; 100 µg/$910
Select
E. coli
None
Biologically active
Less than 1 EU/µg (determined by LAL method).
12.3 kDa
10 µg/$372; 1 mg/$5,021
Viewing 1-25 of 47 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).