IL12RB2

interleukin 12 receptor, beta 2

IL12RB2 is a type I transmembrane protein identified as a subunit of the interleukin 12 receptor complex. The coexpression of this and IL12RB1 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. The expression of this gene is up-regulated by interferon gamma in Th1 cells, and plays a role in Th1 cell differentiation. The up-regulation of this gene is found to be associated with a number of infectious diseases, such as Crohn's disease and leprosy, which is thought to contribute to the inflammatory response and host defense. Several transcript variants encoding different isoforms and non-protein coding transcripts have been found for this gene.

☰ Filters

Products

Proteins (13)

Type

Over-Expression Lysate (2)

Recombinant (11)

Target

IL12RB2 (13)

Application

Bind (1)

ELISA (1)

Func (1)

SDS-PAGE (1)

Publications

No (13)

Tag

6His, N-terminus (1)

Fc, C-terminus (2)

GST (1)

GST, N-terminus (1)

His (3)

His,C-terminus (2)

His-GST (1)

Myc-DDK (Flag) (2)

Species

Human (6)

Mouse (6)

Source

293T Cells (1)

E. coli (4)

HEK 293 Cells (3)

Human Cells (1)

Mammalian Cells (1)

Wheat Germ Extract (2)

Yeast (1)

Purification

Purified (3)

Low Endotoxin Level

Low endotoxin level (4)

Biologically Active

Biologically active (1)

Select

Human IL12RB2 Protein (Recombinant 6His, N-terminus) (aa24-622) - LS-G23450

Source:

Yeast

Tag:

6His, N-terminus

Molecular Weight:

69.7 kD

Price:

100 µg/$446; 20 µg/$336; 1 mg/$1,460

Select

Human IL12RB2 Protein (Recombinant His-GST) (aa559-647) - LS-G13308

Source:

E. coli

Tag:

His-GST

Molecular Weight:

42.6 kDa

Price:

10 µg/$281; 50 µg/$442; 100 µg/$707; 200 µg/$885; 1 mg/$1,994; 500 µg/$1,534; 5 mg/$3,095; 2 mg/$2,181

Select

Mouse IL12RB2 Protein (Recombinant His,C-terminus) (Met1-Asn637) - LS-G51409

Source:

HEK 293 Cells

Tag:

His,C-terminus

Application:

Bind ELISA Func SDS-PAGE

Biological Activity:

Biologically active

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

The secreted recombinant mouse IL12RB2 consists of 625 amino acids and has a predicted molecular mass of 70 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rmIL12RB2 is approximately 120-130 kDa due to glycosylation.

Price:

100 µg/$441; 1 mg/$2,003

Select

Mouse IL12RB2 Protein (Recombinant His,C-terminus) (Met1-Asn637) - LS-G138179

Source:

HEK 293 Cells

Tag:

His,C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

70 kDa

Price:

100 µg/$721

Select

Human IL12RB2 Protein (Recombinant GST, N-terminus) (aa105-214) - LS-G58984

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

Select

Human IL12RB2 Protein (Recombinant GST) (Full Length) - LS-G29045

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

123.5 kDa

Price:

2 µg/$439

Select

Human IL12RB2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G81705

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

97.14 kDa

Price:

20 µg/$150

Select

IL12RB2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G99483

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

97.14 kDa

Price:

100 µg/$494

Select

Mouse IL12RB2 Protein (Recombinant Fc, C-terminus) (Met1-Asn637) - LS-G139261

Source:

Mammalian Cells

Tag:

Fc, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

98.4 kDa

Price:

10 µg/$281; 50 µg/$389

Select

Mouse IL12RB2 Protein (Recombinant Fc, C-terminus) (Met1-Asn637) - LS-G40144

Source:

Human Cells

Tag:

Fc, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

98.4kD

Price:

10 µg/$281; 50 µg/$395; 500 µg/$1,585; 1 mg/$2,157

Select

Human IL12RB2 Protein (Recombinant His) (aa559-647) - LS-G13307

Source:

E. coli

Tag:

His

Molecular Weight:

16.8 kDa

Price:

10 µg/$281; 50 µg/$442; 100 µg/$707; 200 µg/$885; 1 mg/$1,994; 500 µg/$1,534; 5 mg/$3,095; 2 mg/$2,181

Select

Mouse IL12RB2 Protein (Recombinant His) (aa285-441) - LS-G13309

Source:

E. coli

Tag:

His

Molecular Weight:

19.3 kDa

Price:

10 µg/$283; 50 µg/$452; 100 µg/$722; 200 µg/$902; 1 mg/$2,016; 500 µg/$1,553; 5 mg/$3,151; 2 mg/$2,204

Select

Mouse IL12RB2 Protein (Recombinant His) (aa455-606) - LS-G13310

Source:

E. coli

Tag:

His

Molecular Weight:

19.1 kDa

Price:

10 µg/$283; 50 µg/$452; 100 µg/$722; 200 µg/$902; 1 mg/$2,016; 500 µg/$1,553; 5 mg/$3,151; 2 mg/$2,204

Viewing 1-13 of 13 product results

(0) Selected Add Selected To Cart Compare Selected Email Selected Clear Selected Top Of Search

---

Filtered By:

Products: Proteins

Clear Filters

If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.