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IL12RB2

interleukin 12 receptor, beta 2

IL12RB2 is a type I transmembrane protein identified as a subunit of the interleukin 12 receptor complex. The coexpression of this and IL12RB1 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. The expression of this gene is up-regulated by interferon gamma in Th1 cells, and plays a role in Th1 cell differentiation. The up-regulation of this gene is found to be associated with a number of infectious diseases, such as Crohn's disease and leprosy, which is thought to contribute to the inflammatory response and host defense. Several transcript variants encoding different isoforms and non-protein coding transcripts have been found for this gene.

Gene Name: interleukin 12 receptor, beta 2
Family/Subfamily: Interleukin
Synonyms: IL12RB2, Il-12R beta2, IL-12R-beta-2, IL-12 receptor beta 2, Il-12 receptor beta2, IL-12 receptor subunit beta-2, IL-12R subunit beta-2, RP11-102M16.1, IL-12RB2
Target Sequences: NM_001559 NP_001550.1 Q99665

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Products
Antibodies (65)
Primary (65)
IL12RB2 (65)
Human (47)
Mouse (24)
Rat (3)
Bovine (3)
Chimpanzee (3)
Pig (3)
IHC (9)
IHC-P (1)
WB (55)
Flo (9)
ELISA (13)
IF (1)
Peptide-ELISA (1)
rabbit (60)
mouse (5)
Product Group
IHCPlus (1)
IgG (21)
IgG1 (2)
IgG2a (1)
IgG2a,k (1)
monoclonal mc (4)
polyclonal pc (61)
2H6 (1)
305719 (1)
APC (4)
APC Conjugated (7)
Azide-free (1)
Biotin Conjugated (8)
Cy3 Conjugated (4)
Cy7 Conjugated (4)
FITC Conjugated (8)
HRP Conjugated (8)
PE Conjugated (7)
Unconjugated (19)
aa559-647 (16)
aa285-441 (8)
aa455-606 (8)
aa756-783 (7)
aa326-375 (4)
aa24-622 (2)
aa323-695 (1)
No (65)
IL12RB2 Antibody - Anti-IL12RB2 antibody IHC staining of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:50.
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IL12RB2 Rabbit anti-Human Polyclonal (aa756-783) Antibody
Human
Flo, IHC, IHC-P, WB
Unconjugated
200 µl/$460
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IL12RB2 Mouse anti-Human Monoclonal Antibody
Human
WB
Unconjugated
100 µg/$896
IL12RB2 Antibody - Western blot of recombinant IL12RB2.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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IL12RB2 Rabbit anti-Mouse Polyclonal (aa285-441) Antibody
Mouse
WB
Unconjugated
100 µl/$306; 200 µl/$347; 500 µl/$484; 1 ml/$553; 2 ml/$737; 5 ml/$1,206
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IL12RB2 Mouse anti-Human Monoclonal (aa24-622) (PE) Antibody
Mouse, Human
Flo
PE Conjugated
100 Tests/$872
IL12RB2 Antibody - Immunofluorescence staining of HepG2 cells at a dilution of 1:133, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4 °C.The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG (H+L) .
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IL12RB2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF
Unconjugated
50 µg/$294; 100 µg/$360
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IL12RB2 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
Biotin Conjugated
50 µg/$294; 100 µg/$360
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IL12RB2 Mouse anti-Human Monoclonal (aa24-622) (APC) (305719) Antibody
Human
Flo
APC Conjugated
100 Tests/$884
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IL12RB2 Rabbit anti-Human Polyclonal (aa756-783) Antibody
Human
ELISA, Flo, IHC, WB
Unconjugated
200 µl/$734
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IL12RB2 Rabbit anti-Human Polyclonal (aa756-783) (Biotin) Antibody
Human
ELISA, Flo, IHC, WB
Biotin Conjugated
200 µl/$952
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IL12RB2 Rabbit anti-Human Polyclonal (aa756-783) (FITC) Antibody
Human
ELISA, Flo, IHC, WB
FITC Conjugated
200 µl/$952
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IL12RB2 Rabbit anti-Human Polyclonal (aa756-783) (APC) Antibody
Human
ELISA, Flo, IHC, WB
APC Conjugated
200 µl/$952
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IL12RB2 Rabbit anti-Human Polyclonal (aa756-783) (Azide-free) (HRP) Antibody
Human
ELISA, Flo, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
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IL12RB2 Rabbit anti-Human Polyclonal (aa756-783) (PE) Antibody
Human
ELISA, Flo, IHC, WB
PE Conjugated
200 µl/$952
IL12RB2 Antibody - Detection limit for recombinant GST tagged IL12RB2 is approximately 1 ng/ml as a capture antibody.
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IL12RB2 Mouse anti-Human Monoclonal (2H6) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$423
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IL12RB2 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, WB
Unconjugated
100 µg/$357
IL12RB2 Antibody - Sample (30 ug whole cell lysate). A: A431, B: Hep G2 . 7.5% SDS PAGE. IL12RB2 antibody diluted at 1:5000
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IL12RB2 Rabbit anti-Human Polyclonal (aa323-695) Antibody
Human
WB
Unconjugated
100 µl/$450
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IL12RB2 Rabbit anti-Mouse Polyclonal Antibody
Mouse
ELISA
Unconjugated
100 µl/$412
IL12RB2 Antibody - Immunohistochemistry of paraffin-embedded Human prostate cancer using IL12RB2 Polyclonal Antibody at dilution of 1:40.
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IL12RB2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
IL12RB2 Antibody - Immunohistochemistry of paraffin-embedded Human thyroid cancer using IL12RB2 Polyclonal Antibody at dilution of 1:40.
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IL12RB2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
IL12RB2 Antibody - Western blot analysis of IL12RB2 expression in 721_B whole cells lysate. The lane on the left is treated with the antigen-specific peptide.
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IL12RB2 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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IL12RB2 Rabbit anti-Mouse Polyclonal Antibody
Mouse
ELISA
Unconjugated
20 µl/$286; 100 µl/$435
IL12RB2 Antibody - Western blot of recombinant IL12RB2.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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IL12RB2 Rabbit anti-Mouse Polyclonal (aa455-606) Antibody
Mouse
WB
Unconjugated
100 µl/$306; 200 µl/$347; 500 µl/$484; 1 ml/$553; 2 ml/$737; 5 ml/$1,206
IL12RB2 Antibody - Western blot of recombinant IL12RB2.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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IL12RB2 Rabbit anti-Mouse Polyclonal (aa455-606) (Biotin) Antibody
Mouse
WB
Biotin Conjugated
100 µl/$316; 200 µl/$361; 500 µl/$511; 1 ml/$587; 2 ml/$809; 5 ml/$1,317
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IL12RB2 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
100 µg/$749
IL12RB2 Antibody - IL12RB2 antibody Western Blot of 721_B. Antibody dilution: 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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IL12RB2 Rabbit anti-Human Polyclonal (aa326-375) Antibody
Human
WB
Unconjugated
100 µl/$424
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).