IL12RB2

interleukin 12 receptor, beta 2

IL12RB2 is a type I transmembrane protein identified as a subunit of the interleukin 12 receptor complex. The coexpression of this and IL12RB1 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. The expression of this gene is up-regulated by interferon gamma in Th1 cells, and plays a role in Th1 cell differentiation. The up-regulation of this gene is found to be associated with a number of infectious diseases, such as Crohn's disease and leprosy, which is thought to contribute to the inflammatory response and host defense. Several transcript variants encoding different isoforms and non-protein coding transcripts have been found for this gene.

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Antibodies (65)

Proteins (13)

ELISA Kits (2)

Type

Custom (1)

Over-Expression Lysate (2)

Primary (65)

Recombinant (11)

Sandwich (1)

Target

IL12RB2 (80)

Reactivity

Human (49)

Mouse (24)

Rat (3)

Bovine (3)

Chimpanzee (3)

Pig (3)

Application

IHC (9)

IHC-P (1)

WB (55)

Flo (9)

Bind (1)

ELISA (14)

Func (1)

IF (1)

Peptide-ELISA (1)

SDS-PAGE (1)

Host

rabbit (60)

mouse (5)

Product Group

IHCPlus (1)

Isotype

IgG (21)

IgG1 (2)

IgG2a (1)

IgG2a,k (1)

Clonality

monoclonal mc (4)

polyclonal pc (61)

Clone

2H6 (1)

305719 (1)

Format

96-Well Microplate (1)

96-Well Strip Plate (1)

APC (4)

APC Conjugated (7)

Azide-free (1)

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Cy3 Conjugated (4)

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FITC Conjugated (8)

HRP Conjugated (8)

PE Conjugated (7)

Unconjugated (19)

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Epitope

aa559-647 (16)

aa285-441 (8)

aa455-606 (8)

aa756-783 (7)

aa326-375 (4)

aa24-622 (2)

aa323-695 (1)

Publications

No (80)

Sample Type

Plasma (1)

Serum (1)

Tissue Homogenates (1)

Tag

6His, N-terminus (1)

Fc, C-terminus (2)

GST (1)

GST, N-terminus (1)

His (3)

His,C-terminus (2)

His-GST (1)

Myc-DDK (Flag) (2)

Species

Human (6)

Mouse (6)

Source

293T Cells (1)

E. coli (4)

HEK 293 Cells (3)

Human Cells (1)

Mammalian Cells (1)

Wheat Germ Extract (2)

Yeast (1)

Purification

Purified (3)

Low Endotoxin Level

Low endotoxin level (4)

Biologically Active

Biologically active (1)

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IHC-plus™ IL12RB2 Antibody (aa756-783) LS-B10479

(4.0) Rating

Antibody:

IL12RB2 Rabbit anti-Human Polyclonal (aa756-783) Antibody

Reactivity:

Human

Applications:

Flo, IHC, IHC-P, WB

Format:

Unconjugated

Price:

200 µl/$460

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IL12RB2 Antibody LS-C143930

Antibody:

IL12RB2 Mouse anti-Human Monoclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µg/$896

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IL12RB2 Antibody (aa285-441) LS-C294829

Antibody:

IL12RB2 Rabbit anti-Mouse Polyclonal (aa285-441) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$306; 200 µl/$347; 500 µl/$484; 1 ml/$553; 2 ml/$737; 5 ml/$1,206

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IL12RB2 Antibody (aa24-622, PE) LS-C125812

Antibody:

IL12RB2 Mouse anti-Human Monoclonal (aa24-622) (PE) Antibody

Reactivity:

Mouse, Human

Applications:

Flo

Format:

PE Conjugated

Price:

100 Tests/$872

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Human IL12RB2 Protein (Recombinant 6His, N-terminus) (aa24-622) - LS-G23450

Source:

Yeast

Tag:

6His, N-terminus

Molecular Weight:

69.7 kD

Price:

100 µg/$446; 20 µg/$336; 1 mg/$1,460

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Human IL12RB2 Protein (Recombinant His-GST) (aa559-647) - LS-G13308

Source:

E. coli

Tag:

His-GST

Molecular Weight:

42.6 kDa

Price:

10 µg/$281; 50 µg/$442; 100 µg/$707; 200 µg/$885; 1 mg/$1,994; 500 µg/$1,534; 5 mg/$3,095; 2 mg/$2,181

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IL12RB2 Antibody LS-C672013

Antibody:

IL12RB2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

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IL12RB2 Antibody (Biotin) LS-C672014

Antibody:

IL12RB2 Rabbit anti-Human Polyclonal (Biotin) Antibody

Reactivity:

Human

Format:

Biotin Conjugated

Price:

50 µg/$294; 100 µg/$360

• Unconjugated
• Biotin

• Unconjugated
• Biotin

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IL12RB2 Antibody (aa24-622, clone 305719, APC) LS-C125813

Antibody:

IL12RB2 Mouse anti-Human Monoclonal (aa24-622) (APC) (305719) Antibody

Reactivity:

Human

Applications:

Flo

Format:

APC Conjugated

Price:

100 Tests/$884

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IL12RB2 Antibody (aa455-606, Biotin) LS-C299860

Antibody:

IL12RB2 Rabbit anti-Mouse Polyclonal (aa455-606) (Biotin) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$316; 200 µl/$361; 500 µl/$511; 1 ml/$587; 2 ml/$809; 5 ml/$1,317

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IL12RB2 Antibody (aa756-783) LS-C322201

Antibody:

IL12RB2 Rabbit anti-Human Polyclonal (aa756-783) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IHC, WB

Format:

Unconjugated

Price:

200 µl/$734

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IL12RB2 Antibody (aa756-783, Biotin) LS-C215241

Antibody:

IL12RB2 Rabbit anti-Human Polyclonal (aa756-783) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IHC, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

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IL12RB2 Antibody (aa756-783, FITC) LS-C215242

Antibody:

IL12RB2 Rabbit anti-Human Polyclonal (aa756-783) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IHC, WB

Format:

FITC Conjugated

Price:

200 µl/$952

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IL12RB2 Antibody (aa756-783, APC) LS-C215240

Antibody:

IL12RB2 Rabbit anti-Human Polyclonal (aa756-783) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IHC, WB

Format:

APC Conjugated

Price:

200 µl/$952

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IL12RB2 Antibody (aa756-783, Azide-free, HRP) LS-C215244

Antibody:

IL12RB2 Rabbit anti-Human Polyclonal (aa756-783) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IHC, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

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IL12RB2 Antibody (aa756-783, PE) LS-C215245

Antibody:

IL12RB2 Rabbit anti-Human Polyclonal (aa756-783) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IHC, WB

Format:

PE Conjugated

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• APC
• HRP, Azide-free
• PE

• Unconjugated
• Biotin
• FITC
• More...
  • APC
  • HRP, Azide-free
  • PE

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IL12RB2 Antibody (clone 2H6) LS-C197525

Antibody:

IL12RB2 Mouse anti-Human Monoclonal (2H6) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$423

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IL12RB2 Antibody LS-C781096

Antibody:

IL12RB2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$357

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IL12RB2 Antibody (aa323-695) LS-C185526

Antibody:

IL12RB2 Rabbit anti-Human Polyclonal (aa323-695) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$450

Select

Mouse IL12RB2 Protein (Recombinant His,C-terminus) (Met1-Asn637) - LS-G51409

Source:

HEK 293 Cells

Tag:

His,C-terminus

Application:

Bind ELISA Func SDS-PAGE

Biological Activity:

Biologically active

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

The secreted recombinant mouse IL12RB2 consists of 625 amino acids and has a predicted molecular mass of 70 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rmIL12RB2 is approximately 120-130 kDa due to glycosylation.

Price:

100 µg/$441; 1 mg/$2,003

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IL12RB2 Antibody LS-C487312

Antibody:

IL12RB2 Rabbit anti-Mouse Polyclonal Antibody

Reactivity:

Mouse

Applications:

ELISA

Format:

Unconjugated

Price:

100 µl/$412

Select

Mouse IL12RB2 Protein (Recombinant His,C-terminus) (Met1-Asn637) - LS-G138179

Source:

HEK 293 Cells

Tag:

His,C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

70 kDa

Price:

100 µg/$721

Select

IL12RB2 Antibody LS-C406474

Antibody:

IL12RB2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

Select

IL12RB2 Antibody LS-C403238

Antibody:

IL12RB2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

Select

IL12RB2 Antibody LS-C804112

Antibody:

IL12RB2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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