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IL12B / IL12 p40
interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)
IL12B / IL12 p40 is a subunit of interleukin 12, a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. Interleukin 12 is a disulfide-linked heterodimer composed of the 40 kD cytokine receptor like subunit encoded by this gene, and a 35 kD subunit encoded by IL12A. This cytokine is expressed by activated macrophages that serve as an essential inducer of Th1 cells development. This cytokine has been found to be important for sustaining a sufficient number of memory/effector Th1 cells to mediate long-term protection to an intracellular pathogen. Overexpression of this gene was observed in the central nervous system of patients with multiple sclerosis (MS), suggesting a role of this cytokine in the pathogenesis of the disease. The promoter polymorphism of this gene has been reported to be associated with the severity of atopic and non-atopic asthma in children.
| Gene Name: | interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40) |
| Family/Subfamily: | Interleukin |
| Synonyms: | IL12B, CLMF p40, IL-12 p40, IL-12 subunit p40, Interleukin-12 beta chain, Interleukin-12 subunit beta, IL12, subunit p40, Interleukinl-12, Interleukin 12, p40, NKSF, CLMF, CLMF2, IL-12B, NKSF2 |
| Target Sequences: | NM_002187 NP_002178.2 P29460 |
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Antibodies
(124)
Type
Primary
(124)
Target
IL12B / IL12 p40
(124)
Reactivity
Human
(43)
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(26)
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(18)
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(8)
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(8)
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(8)
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(1)
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(8)
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(7)
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(20)
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(1)
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(4)
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(104)
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(6)
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(53)
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(5)
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rabbit
(104)
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(13)
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(2)
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(5)
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(36)
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(9)
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(1)
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(1)
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(1)
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(20)
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(104)
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(2)
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(2)
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(2)
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(6)
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(8)
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(14)
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(3)
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(6)
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(6)
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(11)
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(11)
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(60)
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(7)
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(2)
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(2)
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(2)
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aa211-222
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aa228-277
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Publications
No
(124)
IL12B / IL12 p40 Rabbit anti-Human Polyclonal (aa264-290) Antibody
Human
Flo, IHC, IHC-P, WB
Unconjugated
400 µl/$393
IL12B / IL12 p40 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
50 µg/$294; 100 µg/$360
IL12B / IL12 p40 Rabbit anti-Human Polyclonal (aa23-328) (HRP) Antibody
Human
ELISA, IHC, WB
HRP Conjugated
50 µg/$294; 100 µg/$360
IL12B / IL12 p40 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA, IHC, WB
Biotin Conjugated
50 µg/$294; 100 µg/$360
IL12B / IL12 p40 Mouse anti-Human Monoclonal (I-1A4) Antibody
Human
ELISA, IHC-Fr
Unconjugated
0.5 mg/$534
IL12B / IL12 p40 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
IL12B / IL12 p40 Goat anti-Human Polyclonal (aa278-292) Antibody
Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µg/$503
IL12B / IL12 p40 Mouse anti-Human Monoclonal (2H6) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$423
IL12B / IL12 p40 Rabbit anti-Mouse Polyclonal (aa196-222) (HRP) Antibody
Mouse
ELISA, WB
HRP Conjugated
200 µl/$952
IL12B / IL12 p40 Goat anti-Mouse Polyclonal (aa211-222) Antibody
Mouse, Rat
Peptide-ELISA, WB
Unconjugated
100 µg/$503
IL12B / IL12 p40 Rabbit anti-Sheep Polyclonal Antibody
Sheep
ELISA, WB
Unconjugated
50 µg/$294; 100 µg/$360
IL12B / IL12 p40 Mouse anti-Human Monoclonal (Preservative Free) (6E3E1A8) Antibody
Human
ELISA
Unconjugated, Preservative Free
20 µl/$271; 100 µl/$412
IL12B / IL12 p40 Mouse anti-Human Monoclonal (Preservative Free) (05) Antibody
Human
ELISA
Unconjugated, Preservative Free
20 µl/$286; 100 µl/$435
IL12B / IL12 p40 Rabbit anti-Mouse Polyclonal (aa35-302) Antibody
Mouse
WB
Unconjugated
100 µl/$301; 200 µl/$340; 500 µl/$470; 1 ml/$535; 2 ml/$698; 5 ml/$1,161
IL12B / IL12 p40 Rabbit anti-Sheep Polyclonal (Biotin) Antibody
Sheep
ELISA, WB
Biotin Conjugated
50 µg/$294; 100 µg/$360
IL12B / IL12 p40 Rabbit anti-Dog Polyclonal (aa23-329) Antibody
Dog
WB
Unconjugated
100 µl/$311; 200 µl/$355; 500 µl/$499; 1 ml/$571; 2 ml/$777; 5 ml/$1,261
IL12B / IL12 p40 Rabbit anti-Human Polyclonal (aa264-290) Antibody
Human
ELISA, Flo, IHC, WB
Unconjugated
200 µl/$734
IL12B / IL12 p40 Rabbit anti-Human Polyclonal (aa264-290) (Biotin) Antibody
Human
ELISA, Flo, IHC, WB
Biotin Conjugated
200 µl/$952
IL12B / IL12 p40 Rabbit anti-Human Polyclonal (aa264-290) (FITC) Antibody
Human
Flo, IHC, WB
FITC Conjugated
200 µl/$952
IL12B / IL12 p40 Rabbit anti-Human Polyclonal (aa264-290) (APC) Antibody
Human
ELISA, Flo, IHC, WB
APC Conjugated
200 µl/$952
IL12B / IL12 p40 Rabbit anti-Human Polyclonal (aa264-290) (PE) Antibody
Human
ELISA, Flo, IHC, WB
PE Conjugated
200 µl/$952
IL12B / IL12 p40 Rabbit anti-Rat Monoclonal (Preservative Free) (010) Antibody
Rat
ELISA
Unconjugated, Preservative Free
100 µl/$412
IL12B / IL12 p40 Rabbit anti-Rat Monoclonal (Preservative Free) (106) Antibody
Rat
ELISA
Unconjugated, Preservative Free
100 µl/$412
IL12B / IL12 p40 Rabbit anti-Rat Polyclonal Antibody
Rat
ELISA, IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
IL12B / IL12 p40 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
Viewing 1-25
of 124
product results
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