IL12A / p35

interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)

IL12A / p35 is a subunit of a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. The cytokine is a disulfide-linked heterodimer composed of the 35-kD subunit encoded by this gene, and a 40-kD subunit that is a member of the cytokine receptor family. This cytokine is required for the T-cell-independent induction of interferon (IFN)-gamma, and is important for the differentiation of both Th1 and Th2 cells. The responses of lymphocytes to this cytokine are mediated by the activator of transcription protein STAT4. Nitric oxide synthase 2A (NOS2A/NOS2) is found to be required for the signaling process of this cytokine in innate immunity.

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Products

Proteins (12)

Type

Over-Expression Cell Culture Supernatant (1)

Over-Expression Lysate (1)

Recombinant (10)

Target

IL12A / p35 (12)

Publications

No (12)

Tag

6His, C-terminus (1)

6His, N-terminus (2)

GST, N-terminus (1)

His (1)

His, N-Terminal (3)

His-S (1)

His-T7 (1)

Species

Human (7)

Mouse (2)

Pig (1)

Rat (2)

Source

E. coli (6)

HEK 293 Cells (2)

Mammalian Cells (3)

Wheat Germ Extract (1)

Purification

Purified (3)

Low Endotoxin Level

Low endotoxin level (2)

Biologically Active

Biologically active (1)

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Mouse IL12A / p35 Protein (Recombinant His, N-Terminal) (aa23-215) - LS-G23862

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

25.4 kDa

Price:

10 µg/$284; 50 µg/$462; 100 µg/$737; 200 µg/$922; 1 mg/$2,042; 500 µg/$1,577; 5 mg/$3,221; 2 mg/$2,231

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Human IL12A / p35 Protein (Recombinant) (aa23-219) - LS-G5725

Source:

Mammalian Cells

Tag:

None

Biological Activity:

Biologically active

Molecular Weight:

75 kDa

Price:

10 µg/$388; 500 µg/$3,025; 100 µg/$1,466

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Human IL12A / p35 Protein (Recombinant GST, N-terminus) (aa144-253) - LS-G58982

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human IL12A / p35 Protein (Recombinant His, N-Terminal) - LS-G132803

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

55kDa

Price:

10 µg/$291; 50 µg/$502; 200 µg/$1,002; 100 µg/$802; 1 mg/$2,144; 500 µg/$1,668; 5 mg/$3,501; 2 mg/$2,334

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Rat IL12A / p35 Protein (Recombinant 6His, C-terminus) (Met23-Ser335) - LS-G140712

Source:

Mammalian Cells

Tag:

6His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

59.3 kDa

Price:

10 µg/$317; 50 µg/$524

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Mouse IL12A / p35 Protein (Recombinant His-T7) (aa23-215) - LS-G24596

Source:

E. coli

Tag:

His-T7

Molecular Weight:

25.4 kDa

Price:

10 µg/$289; 50 µg/$490; 100 µg/$782; 200 µg/$977; 1 mg/$2,114; 500 µg/$1,640; 5 mg/$3,417; 2 mg/$2,304

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Rat IL12A / p35 Protein (Recombinant His) (aa23-215) - LS-G23895

Source:

E. coli

Tag:

His

Molecular Weight:

25.5 kDa

Price:

10 µg/$282; 50 µg/$450; 100 µg/$717; 200 µg/$897; 1 mg/$2,010; 500 µg/$1,547; 5 mg/$3,137; 2 mg/$2,198

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Pig IL12A / p35 Protein (Recombinant His-S) (aa26-215) - LS-G23863

Source:

E. coli

Tag:

His-S

Molecular Weight:

24.6 kDa

Price:

10 µg/$289; 50 µg/$490; 100 µg/$782; 200 µg/$977; 1 mg/$2,114; 500 µg/$1,640; 5 mg/$3,417; 2 mg/$2,304

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Human IL12A / p35 Protein (Over-Expression Lysate 6His, N-terminus) (Arg23-Ser219) - LS-G26772

Source:

HEK 293 Cells

Tag:

6His, N-terminus

Molecular Weight:

22 kDa

Price:

100 µg/$298

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Human IL12A / p35 Protein (Over-Expression Cell Culture Supernatant 6His, N-terminus) (Arg23-Ser219) - LS-G26917

Source:

HEK 293 Cells

Tag:

6His, N-terminus

Molecular Weight:

22 kDa

Price:

200 µl/$283

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Human IL12A / p35 Protein (Recombinant His, N-Terminal) (aa23-219) - LS-G11412

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

28.9 kDa

Price:

10 µg/$283; 50 µg/$452; 100 µg/$722; 200 µg/$902; 1 mg/$2,016; 500 µg/$1,553; 5 mg/$3,151; 2 mg/$2,204

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Human IL12A / p35 Protein (Recombinant) (Arg23-Ser219) - LS-G140485

Source:

Mammalian Cells

Tag:

None

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

57.2 kDa

Price:

10 µg/$317; 50 µg/$524

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