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IL12A / p35

interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)

IL12A / p35 is a subunit of a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. The cytokine is a disulfide-linked heterodimer composed of the 35-kD subunit encoded by this gene, and a 40-kD subunit that is a member of the cytokine receptor family. This cytokine is required for the T-cell-independent induction of interferon (IFN)-gamma, and is important for the differentiation of both Th1 and Th2 cells. The responses of lymphocytes to this cytokine are mediated by the activator of transcription protein STAT4. Nitric oxide synthase 2A (NOS2A/NOS2) is found to be required for the signaling process of this cytokine in innate immunity.

Gene Name: interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)
Family/Subfamily: Interleukin
Synonyms: IL12A, CLMF p35, IL-12, subunit p35, IL-12A, Interleukin-12 alpha chain, NFSK, p35, Interleukin-12 subunit alpha, NKSF1, CLMF, IL-12 subunit p35, IL35 subunit, Interleukin 12, p35
Target Sequences: NM_000882 NP_000873.2 P29459

Publications (1)

1
IL35-Producing B Cells Promote the Development of Pancreatic Neoplasia. Pylayeva-Gupta Y, Das S, Handler JS, Hajdu CH, Coffre M, Koralov SB, Bar-Sagi D. Cancer discovery. 2016 6:247-55. (WB; Human) [Full Text Article] [PubMed:26715643] [PMC:PMC5709038]

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ELISA Kits (21)
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IL12A / p35 (21)
Human (5)
Mouse (3)
Rat (3)
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Goat (1)
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96-Well Microplate (3)
96-Well Strip Plate (17)
Antibody Pair and Standard (1)
No (21)
Cell Culture Supernatants (8)
Cell Lysates (7)
Plasma (18)
Serum (18)
Tissue Homogenates (11)
IL12A / p35 ELISA Kit
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Sandwich
96-Well Strip Plate
Human
31.2 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates
1 Plate/$441
IL12A / p35 ELISA Kit
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Sandwich
96-Well Strip Plate
Human
1.56 - 100 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$723
IL12A / p35 ELISA Kit
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Sandwich
96-Well Strip Plate
Dog
15.63 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$748
IL12A / p35 ELISA Kit
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Sandwich
96-Well Microplate
Mouse
15.625 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$586
IL12A / p35 ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
15.63 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$782
IL12A / p35 ELISA Kit
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Sandwich
96-Well Strip Plate
Chicken
15.63 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$715
IL12A / p35 ELISA Kit
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Sandwich
96-Well Strip Plate
Rat
15.63 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$715
IL12A / p35 ELISA Kit
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Sandwich
96-Well Strip Plate
Bovine
7.81 - 500 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$779
IL12A / p35 ELISA Kit
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Sandwich
96-Well Strip Plate
Goat
15.63 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$795
IL12A / p35 ELISA Kit
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Sandwich
96-Well Strip Plate
Horse
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$795
IL12A / p35 ELISA Kit
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Sandwich
96-Well Strip Plate
Pig
15.63 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$779
IL12A / p35 ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$585
IL12A / p35 ELISA Kit
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Custom
96-Well Strip Plate
Rat
Colorimetric - 450nm (TMB)
1 Plate/$585
IL12A / p35 ELISA Kit
Select
Custom
96-Well Strip Plate
Pig
Colorimetric - 450nm (TMB)
1 Plate/$669
IL12A / p35 ELISA Kit
Select
Custom
96-Well Strip Plate
Dog
Colorimetric - 450nm (TMB)
1 Plate/$669
IL12A / p35 ELISA Kit
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Sandwich
96-Well Strip Plate
Bovine
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
IL12A / p35 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
IL12A / p35 ELISA Kit
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Sandwich
96-Well Strip Plate
Bovine
6.25 - 400 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$1,002
IL12A / p35 ELISA Kit
Select
Development Kit
Antibody Pair and Standard
Human
15.62 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
500 Wells/$1,182; 1000 Wells/$1,747
IL12A / p35 ELISA Kit
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Sandwich
96-Well Microplate
Rat
15.625 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$586
IL12A / p35 ELISA Kit
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Sandwich
96-Well Microplate
Human
7.813 - 500 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$586
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).