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IL10RA

interleukin 10 receptor, alpha

IL10RA is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene.

Gene Name: interleukin 10 receptor, alpha
Family/Subfamily: Interleukin
Synonyms: IL10RA, CD210, CD210a, CD210 antigen, IBD28, IL-10R subunit 1, Il-10r, IL-10R subunit alpha, Interleukin 10 receptor, alpha, IL10R, Interleukin-10 receptor, HIL-10R, CDW210A, IL-10 receptor subunit alpha, IL-10R1, IL-10RA, Interleukin-10 receptors, IL-10 RA
Target Sequences: NM_001558 NP_001549.2 Q13651

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Products
Proteins (12)
Over-Expression Cell Culture Supernatant (1)
Over-Expression Lysate (2)
Recombinant (9)
IL10RA (12)
No (12)
6His, N-terminus (1)
His (2)
His, C-Terminal (1)
His, N-Terminal (1)
His,C-terminus (1)
His-GST (1)
Human IgG1 Fc, N-terminus (1)
Myc-DDK (Flag) (3)
Human (9)
Mouse (1)
Rat (1)
293T Cells (1)
E. coli (4)
HEK 293 Cells (4)
Human (1)
Insect Cells (1)
Mammalian Cells (1)
Purified (2)
Low endotoxin level (4)
Biologically active (1)
IL10RA Protein - Purified recombinant protein IL10RA was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
60.8 kDa
20 µg/$1,107
IL10RA Protein
Select
Insect Cells
His
Less than 1.0 EU/µg protein (determined by LAL method).
50 µg/$361; 250 µg/$985; 10 µg/$261
IL10RA Protein - Eukaryotic Interleukin 10 By SDS-PAGE
Select
Human
None
20.3kDa
50 µg/$737; 10 µg/$328; 200 µg/$1,345; 100 µg/$1,139; 1 mg/$2,624; 500 µg/$2,120; 5 mg/$5,153; 2 mg/$2,815
Select
E. coli
His, C-Terminal
Less than 1.0 EU/µg protein (determined by LAL method).
25.2kD
10 µg/$321; 50 µg/$534; 500 µg/$1,869; 1 mg/$2,991
Select
E. coli
His, N-Terminal
24 kDa
10 µg/$265; 50 µg/$315
IL10RA Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
62.9 kDa
100 µg/$494
IL10RA Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
62.9 kDa
20 µg/$150
Select
HEK 293 Cells
Human IgG1 Fc, N-terminus
Biologically active
Less than 5.0 EU/mg protein (determined by LAL method).
~70 kDa (SDS-PAGE)
50 µg/$442
Select
Mammalian Cells
His,C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
25.2 kDa
10 µg/$317; 50 µg/$524
Select
HEK 293 Cells
6His, N-terminus
24 kDa
200 µl/$283
IL10RA Protein - Recombinant Interleukin 10 Receptor Alpha By SDS-PAGE
Select
E. coli
His
13.5 kDa
10 µg/$292; 50 µg/$512; 100 µg/$817; 200 µg/$1,018; 1 mg/$2,168; 500 µg/$1,690; 5 mg/$3,571; 2 mg/$2,359
IL10RA Protein - Recombinant Interleukin 10 Receptor Alpha By SDS-PAGE
Select
E. coli
His-GST
58.7 kDa
10 µg/$296; 50 µg/$537; 100 µg/$860; 200 µg/$1,057; 1 mg/$2,229; 500 µg/$1,745; 5 mg/$3,753; 2 mg/$2,420
Viewing 1-12 of 12 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).