IL-10

interleukin 10

IL-10 is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. Mutations in this gene are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis.

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Proteins (70)

Type

Over-Expression Lysate (2)

Recombinant (68)

Target

IL-10 (70)

Product Group

Coronavirus Antibodies Proteins cDNAs (70)

Cytokine Release Syndrome (70)

Cytokine Release Syndrome Proteins (70)

Format

Animal-free (1)

Publications

No (70)

Tag

10His, C-terminus (2)

10His, N-terminus + Myc, C-terminus (1)

6His, N-terminus (1)

6His-B2M, N-terminus (1)

6His-SUMO, N-terminus (1)

GST (2)

GST, N-terminus (1)

His (9)

His, N-Terminal (5)

His,C-terminus (1)

His-GST (2)

His-GST, N-terminus (1)

His-S (1)

His-T7 (4)

Human IgG1 Fc (1)

Human Mutant IgG1 Fc (1)

Mouse Mutant IgG2a Fc (1)

Myc-DDK (Flag) (3)

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Species

Bovine (3)

Dog (2)

Horse (1)

Human (31)

Marmoset (1)

Mouse (14)

Pig (1)

Rabbit (2)

Rat (7)

Rhesus monkey (6)

Sheep (1)

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Source

293F Cells (4)

293T Cells (1)

Baculovirus (2)

CHO Cells (6)

E. coli (35)

HEK 293 Cells (6)

Human (1)

Human Cells (1)

Mammalian Cells (2)

NS1 Cells (1)

Wheat Germ Extract (2)

Yeast (6)

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Purification

Purified (28)

Low Endotoxin Level

Low endotoxin level (27)

Biologically Active

Biologically active (24)

Animal-free

Animal-free (1)

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Rabbit IL-10 Protein (Recombinant His, N-Terminal) (Ser19-Ser178) - LS-G132770

Source:

293F Cells

Tag:

His, N-Terminal

Molecular Weight:

20kDa

Price:

10 µg/$321; 50 µg/$692; 200 µg/$1,284; 100 µg/$1,082; 1 mg/$2,544; 500 µg/$2,042; 5 mg/$4,831; 2 mg/$2,736

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Human IL-10 Protein (Recombinant) (aa19-178) - LS-G5731

Source:

E. coli

Tag:

None

Biological Activity:

Biologically active

Molecular Weight:

18.6 kDa

Price:

10 µg/$388; 100 µg/$1,466; 500 µg/$3,025

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Rhesus monkey IL-10 Protein (Recombinant 10His, C-terminus) (aa19-178) - LS-G57044

Source:

Mammalian Cells

Tag:

10His, C-terminus

Price:

100 µg/$1,009; 20 µg/$431; 1 mg/$3,451

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Rabbit IL-10 Protein (Recombinant His, N-Terminal) (Ser19-Ser178) - LS-G132662

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

22.1kDa

Price:

10 µg/$297; 50 µg/$542; 200 µg/$1,065; 100 µg/$865; 1 mg/$2,239; 500 µg/$1,755; 5 mg/$3,781; 2 mg/$2,430

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Mouse IL-10 Protein (Recombinant) - LS-G199

Source:

E. coli

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 0.1 ng/µg of protein (less than 1EU/µg).

Molecular Weight:

18.7 kDa

Price:

2 µg/$268; 10 µg/$349

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Human IL-10 Protein (Recombinant His,C-terminus) - LS-G134254

Source:

HEK 293 Cells

Tag:

His,C-terminus

Biological Activity:

Biologically active

Endotoxin Level:

Less than 0.01 EU/µg protein (determined by LAL method).

Molecular Weight:

~18 kDa (SDS-PAGE)

Price:

10 µg/$358

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Mouse IL-10 Protein (Recombinant His, N-Terminal) (Ser19-Ser178) - LS-G132897

Source:

293F Cells

Tag:

His, N-Terminal

Molecular Weight:

22kDa

Price:

10 µg/$283; 50 µg/$452; 200 µg/$902; 100 µg/$722; 1 mg/$2,016; 500 µg/$1,553; 5 mg/$3,151; 2 mg/$2,204

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Human IL-10 Protein (Recombinant GST) (aa19-178) - LS-G22333

Source:

E. coli

Tag:

GST

Molecular Weight:

46 kD

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

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Rhesus monkey IL-10 Protein (Recombinant 10His, N-terminus + Myc, C-terminus) (aa19-178) - LS-G55959

Source:

Baculovirus

Tag:

10His, N-terminus + Myc, C-terminus

Price:

100 µg/$920; 20 µg/$411; 1 mg/$1,808

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Rat IL-10 Protein (Recombinant) - LS-G410

Source:

E. coli

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 0.1 ng/µg of protein (less than 1EU/µg).

Molecular Weight:

18.7 kDa

Price:

2 µg/$268; 10 µg/$349

Select

Human IL-10 Protein (Recombinant His) - LS-G3479

Source:

E. coli

Tag:

His

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Price:

100 µg/$316; 0.5 mg/$526

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Human IL-10 Protein (Recombinant) - LS-G166

Source:

E. coli

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 0.1 ng/µg of protein (less than 1EU/µg).

Molecular Weight:

18.6 kDa

Price:

2 µg/$268; 10 µg/$349

Select

Human IL-10 Protein (Recombinant) - LS-G3641

Source:

E. coli

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 0.01 ng/µg of protein (Less than 0.1 EU/µg).

Price:

2 µg/$281; 10 µg/$369

• Unmodified
• Animal-free

• Unmodified
• Animal-free

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Mouse IL-10 Protein (Recombinant) (aa19-178) - LS-G5881

Source:

E. coli

Tag:

None

Biological Activity:

Biologically active

Molecular Weight:

18.7 kDa

Price:

10 µg/$388; 100 µg/$1,466; 500 µg/$3,025

Select

Human IL-10 Protein (Recombinant GST) (Full Length) - LS-G29042

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

46.9 kDa

Price:

10 µg/$479; 25 µg/$670

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Human IL-10 Protein (Recombinant) - LS-G37685

Tag:

None

Biological Activity:

Biologically active

Molecular Weight:

18.6 kD

Price:

10 µg/$484

Select

Mouse IL-10 Protein (Recombinant) - LS-G37815

Tag:

None

Biological Activity:

Biologically active

Molecular Weight:

18.7 kD

Price:

10 µg/$484

Select

Mouse IL-10 Protein (Recombinant) (Ser19-Ser178) - LS-G39138

Source:

E. coli

Tag:

None

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

18.9kD

Price:

10 µg/$321; 50 µg/$534; 500 µg/$1,585; 1 mg/$2,353

Select

Rat IL-10 Protein (Recombinant) - LS-G37871

Tag:

None

Biological Activity:

Biologically active

Molecular Weight:

18.7 kD

Price:

10 µg/$492

Select

Human IL-10 Protein (Recombinant) (aa19-178) - LS-G55909

Source:

Human

Tag:

None

Price:

50 µg/$837; 10 µg/$345; 200 µg/$1,476; 100 µg/$1,255; 1 mg/$2,783; 500 µg/$2,279; 5 mg/$5,860; 2 mg/$3,125

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Human IL-10 Protein (Recombinant GST, N-terminus) (aa74-178) - LS-G58979

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human IL-10 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G87440

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

20.52 kDa

Price:

20 µg/$150

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Rhesus monkey IL-10 Protein (Recombinant 10His, C-terminus) (aa19-178) - LS-G55988

Source:

Baculovirus

Tag:

10His, C-terminus

Price:

100 µg/$810; 20 µg/$387; 1 mg/$1,678

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Human IL-10 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G70560

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

18.6 kDa

Price:

20 µg/$1,107

Select

Human IL-10 Protein (Recombinant) (Ser19-Asn178) - LS-G39443

Source:

Human Cells

Tag:

None

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

19.6kD

Price:

10 µg/$321; 50 µg/$534; 500 µg/$1,680; 1 mg/$2,353

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