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IHH
Indian hedgehog
Intercellular signal essential for a variety of patterning events during development. Binds to the patched (PTC) receptor, which functions in association with smoothened (SMO), to activate the transcription of target genes. Implicated in endochondral ossification: may regulate the balance between growth and ossification of the developing bones. Induces the expression of parathyroid hormone-related protein (PTHRP).
| Gene Name: | Indian hedgehog |
| Family/Subfamily: | Protease , Cysteine C46 |
| Synonyms: | IHH, Indian hedgehog, Indian hedgehog homolog, Indian hedgehog protein, HHG2, BDA1, HHG-2 |
| Target Sequences: | BC034757 Q14623 Q14623 |
Publications (1)
1
Indian Hedgehog release from TNF-activated renal epithelia drives local and remote organ fibrosis. Eoin D O'Sullivan, Katie J Mylonas, Cuiyan Xin, David P Baird, Cyril Carvalho, Marie-Helena Docherty, Ross Campbell, Kylie P Matchett, Scott H Waddell, Alexander D Walker, Kevin M Gallagher, Siyang Jia, Steve Leung, Alexander Laird, Julia Wilflingseder, Michaela Willi, Maximilian Reck, Sarah Finnie, Angela Pisco, Sabrina Gordon-Keylock, Alexander Medvinsky, Luke Boulter, Neil C Henderson, Kristina Kirschner, Tamir Chandra, Bryan R Conway, Jeremy Hughes, Laura Denby, Joseph V Bonventre, David A F. Science translational medicine. 2023 May;15:eabn0736. [Full Text Article]
[PubMed:37256934]
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IHH Rabbit anti-Human Polyclonal (aa24-73) Antibody
Mouse, Wallaby, Human
IHC, IHC-Pfa, WB
Unconjugated
100 µl/$397
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$730
Sandwich
96-Well Strip Plate
Rat
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$783
Sandwich
96-Well Strip Plate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$748
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
IHH Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
20 µl/$275; 100 µl/$389
IHH Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
IHH Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
IHH Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$460
Sandwich
96-Well Strip Plate
Mouse
31.2 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
IHH Rabbit anti-Human Polyclonal (aa51-80) Antibody
Human
ELISA, IHC, WB
Unconjugated
200 µl/$734
IHH Rabbit anti-Human Polyclonal (aa51-80) (APC) Antibody
Human
ELISA, IHC, WB
APC Conjugated
200 µl/$952
IHH Rabbit anti-Human Polyclonal (N-Terminus) Antibody
IHC, IP, WB
Unconjugated
200 µl/$734
IHH Rabbit anti-Human Polyclonal (N-Terminus) (APC) Antibody
Human
ELISA, IHC, IP, WB
APC Conjugated
200 µl/$952
IHH Mouse anti-Human Monoclonal (2G9) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$423
IHH Rabbit anti-Human Polyclonal (aa169-200) Antibody
Mouse, Human
ELISA, WB
Unconjugated
200 µl/$734
IHH Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
IHH Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Human
WB
Unconjugated
100 µl/$321
E. coli
None
Biologically active
19.8 kDa
5 µg/$282; 100 µg/$1,116; 500 µg/$2,095
IHH Rabbit anti-Human Polyclonal (aa240-399) Antibody
Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
IHH Rabbit anti-Human Polyclonal (aa51-80) Antibody
Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
IHH Rat anti-Mouse Monoclonal Antibody
Mouse
ELISA, WB
Unconjugated
500 µg/$1,079
IHH Rabbit anti-Mouse Polyclonal (aa169-200) Antibody
Mouse, Human
WB
Unconjugated
400 µl/$393
293T Cells
Myc-DDK (Flag)
45.25 kDa
20 µg/$150
E. coli
His
26.7 kD
1 mg/$1,355; 100 µg/$420; 20 µg/$323
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