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IGFBP2 / IGF-BP53

insulin-like growth factor binding protein 2, 36kDa

Inhibits IGF-mediated growth and developmental rates. IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.

Gene Name: insulin-like growth factor binding protein 2, 36kDa
Synonyms: IGFBP2, BP2, IGFBP-2, IGF-binding protein 2, IBP-2, IBP2, IGF-BP53
Target Sequences: NM_000597 NP_000588.2 P18065

Publications (1)

1
Linking patient outcome to high throughput protein expression data identifies novel regulators of colorectal adenocarcinoma aggressiveness. French CL, Ye F, Revetta F, Zhang B, Coffey RJ, Washington MK, Deane NG, Beauchamp RD, Weaver AM. F1000Research. 2015 4:99. (WB; Human) [Full Text Article] [PubMed:26097693] [PMC:PMC4457132]

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Products
Proteins (12)
Over-Expression Cell Culture Supernatant (1)
Over-Expression Lysate (3)
Recombinant (8)
IGFBP2 / IGF-BP53 (12)
No (12)
Fc (1)
GST (1)
His, C-Terminal (1)
His, N-Terminal (2)
His-GST (1)
His-S (1)
His-T7 (1)
Myc-DDK (Flag) (3)
Human (8)
Mouse (2)
Rat (1)
293T Cells (1)
E. coli (3)
HEK 293 Cells (5)
High Five Cells (1)
Human Cells (1)
Wheat Germ Extract (1)
Purified (3)
Low endotoxin level (3)
Biologically active (2)
Select
HEK 293 Cells
His, C-Terminal
Biologically active
Less than 0.2 EU/µg protein (determined by LAL method).
6-20 kDa (SDS-PAGE)
50 µg/$432; 10 µg/$262; 1 mg/$2,449
IGFBP2 / IGF-BP53 Protein - Recombinant  Insulin Like Growth Factor Binding Protein 2 By SDS-PAGE
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E. coli
His-T7
23.7 kDa
10 µg/$282; 50 µg/$447; 100 µg/$715; 200 µg/$892; 1 mg/$2,005; 500 µg/$1,543; 5 mg/$3,123; 2 mg/$2,192
Select
High Five Cells
None
Biologically active
Less than 0.1 ng/µg of protein (less than 1EU/µg).
31.5 kDa
5 µg/$268; 20 µg/$349
IGFBP2 / IGF-BP53 Protein - Purified recombinant protein IGFBP2 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
35 kDa
20 µg/$1,107
IGFBP2 / IGF-BP53 Protein - Recombinant Insulin Like Growth Factor Binding Protein 2 By SDS-PAGE
Select
E. coli
His-GST
61.6 kDa
10 µg/$281; 50 µg/$442; 100 µg/$705; 200 µg/$882; 1 mg/$1,989; 500 µg/$1,529; 5 mg/$3,081; 2 mg/$2,176
Select
E. coli
His-S
35.0 kDa
10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119
IGFBP2 / IGF-BP53 Protein - 12.5% SDS-PAGE of human IGFBP2 stained with Coomassie Blue
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Wheat Germ Extract
GST
61.5 kDa
2 µg/$439
Select
293T Cells
Myc-DDK (Flag)
35 kDa
20 µg/$150
Select
HEK 293 Cells
His, N-Terminal
~31 kDa
200 µl/$283
Select
HEK 293 Cells
His, N-Terminal
~31 kDa
100 µg/$298
IGFBP2 / IGF-BP53 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
35 kDa
100 µg/$494
Select
Human Cells
Fc
Less than 1.0 EU/µg protein (determined by LAL method).
56.6 kDa
100 µg/$926
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).