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IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Promotes cell migration.
Gene Name: | insulin-like growth factor binding protein 1 |
Synonyms: | IGFBP1, AFBP, Amniotic fluid binding protein, Binding protein-26, Binding protein-25, Binding protein-28, IGF-binding protein 1, IGF-BP25, IBP1, HIGFBP-1, PP12, Placental protein 12, IBP-1, IGFBP-1 |
Target Sequences: | NM_000596 NP_000587.1 P08833 |
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