IFNL2 / IL28A

interferon, lambda 2

Cytokine with antiviral, antitumour and immunomodulatory activities. Plays a critical role in the antiviral host defense, predominantly in the epithelial tissues. Acts as a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IFNLR1, and receptor engagement leads to the activation of the JAK/STAT signaling pathway resulting in the expression of IFN-stimulated genes (ISG), which mediate the antiviral state. Has a restricted receptor distribution and therefore restricted targets: is primarily active in epithelial cells and this cell type-selective action is because of the epithelial cell-specific expression of its receptor IFNLR1. Seems not to be essential for early virus-activated host defense in vaginal infection, but plays an important role in Toll-like receptor (TLR)-induced antiviral defense. Plays a significant role in the antiviral immune defense in the intestinal epithelium. Exerts an immunomodulatory effect by up-regulating MHC class I antigen expression.

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Products

Antibodies (47)

ELISA Kits (14)

Proteins (9)

Type

Development Kit (1)

Over-Expression Lysate (2)

Primary (47)

Recombinant (7)

Sandwich (11)

Sandwich CLIA (2)

Target

IFNL2 / IL28A (70)

Reactivity

Human (54)

Mouse (10)

Rat (2)

Application

IHC (3)

IHC-P (1)

WB (43)

ELISA (10)

IF (1)

Neut (1)

Peptide-ELISA (1)

Host

rabbit (19)

mouse (27)

rat (1)

Product Group

DevKit DuoPlus (1)

IHCPlus (1)

Isotype

IgG (5)

IgG1 (3)

IgG2b (1)

IgG2b,k (24)

Clonality

monoclonal mc (29)

polyclonal pc (18)

Clone

11n112 (1)

129 (1)

1H10 (1)

6H9E6 (1)

7B9A4 (1)

C9 (8)

Format

12 x 8-Well Microstrips (1)

96-Well Microplate (2)

96-Well Strip Plate (10)

Antibody Pair and Standard (1)

APC (4)

APC Conjugated (4)

Biotin Conjugated (5)

Cy3 Conjugated (4)

Cy7 Conjugated (4)

FITC Conjugated (4)

HRP Conjugated (4)

PE Conjugated (4)

Preservative Free (1)

Unconjugated (18)

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Epitope

aa26-200 (8)

Internal (1)

aa20-193 (1)

aa61-92 (1)

Publications

No (70)

Sample Type

Cell Culture Supernatants (6)

Cell Lysates (5)

Plasma (13)

Serum (13)

Tissue Homogenates (5)

Tag

6His, C-terminus (2)

His (1)

His, N-Terminal (1)

His-GST (1)

Myc-DDK (Flag) (2)

Species

Human (7)

Mouse (1)

Source

293T Cells (1)

E. coli (5)

HEK 293 Cells (1)

Human Cells (1)

Mammalian Cells (1)

Purification

Purified (3)

Low Endotoxin Level

Low endotoxin level (4)

Biologically Active

Biologically active (2)

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IHC-plus™ IFNL2 / IL28A Antibody LS-B7476

(4.0) Rating

Antibody:

IFNL2 / IL28A Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$485

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IFNL2 / IL28A Antibody (Biotin) LS-C104833

Antibody:

IFNL2 / IL28A Rabbit anti-Human Polyclonal (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Biotin Conjugated

Price:

25 µg/$356; 50 µg/$396

• Unconjugated
• Biotin

• Unconjugated
• Biotin

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Human IFNL2 / IL28A (Sandwich ELISA) ELISA Kit - LS-F4909

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.78 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$798

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Mouse IFNL2 / IL28A (CLIA) ELISA Kit - LS-F26272

Type:

Sandwich CLIA

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

1.37 - 1000 pg/ml

Detection:

Chemiluminescent

Sample Types:

Plasma, Serum

Price:

1 Plate/$871

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IFNL2 / IL28A Antibody (clone 1H10) LS-C666409

Antibody:

IFNL2 / IL28A Mouse anti-Human Monoclonal (1H10) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$361

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IFNL2 / IL28A Antibody (clone 7B9A4) LS-C669400

Antibody:

IFNL2 / IL28A Mouse anti-Human Monoclonal (7B9A4) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µl/$459

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IFNL2 / IL28A Antibody (clone 129, Preservative Free) LS-C819353

Antibody:

IFNL2 / IL28A Rabbit anti-Mouse Monoclonal (Preservative Free) (129) Antibody

Reactivity:

Mouse

Applications:

ELISA

Format:

Unconjugated, Preservative Free

Price:

100 µl/$412

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Human IFNL2 / IL28A (Sandwich ELISA) ELISA Kit - LS-F645

Type:

Sandwich

Format:

12 x 8-Well Microstrips

Reactivity:

Human

Range:

125 - 8000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Plasma, Serum

Price:

1 Plate/$534

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IFNL2 / IL28A Antibody (clone 6H9E6) LS-C669402

Antibody:

IFNL2 / IL28A Mouse anti-Human Monoclonal (6H9E6) Antibody

Reactivity:

Human

Applications:

ELISA, IF, WB

Format:

Unconjugated

Price:

100 µl/$459

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IFNL2 / IL28A Antibody LS-C666410

Antibody:

IFNL2 / IL28A Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$386

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IFNL2 / IL28A Antibody LS-C743272

Antibody:

IFNL2 / IL28A Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

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IFNL2 / IL28A Antibody LS-C802417

Antibody:

IFNL2 / IL28A Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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IFNL2 / IL28A Antibody LS-C487564

Antibody:

IFNL2 / IL28A Rabbit anti-Mouse Polyclonal Antibody

Reactivity:

Mouse

Applications:

ELISA

Format:

Unconjugated

Price:

100 µl/$412

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IFNL2 / IL28A Antibody LS-C487565

Antibody:

IFNL2 / IL28A Rabbit anti-Mouse Polyclonal Antibody

Reactivity:

Mouse

Applications:

ELISA

Format:

Unconjugated

Price:

100 µl/$412

Select

IFNL2 / IL28A Antibody (aa20-193, clone 11n112) LS-C184832

Antibody:

IFNL2 / IL28A Rat anti-Mouse Monoclonal (aa20-193) (11n112) Antibody

Reactivity:

Mouse

Applications:

Neut

Format:

Unconjugated

Price:

500 µg/$1,089

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IFNL2 / IL28A Antibody (clone C9) LS-C664020

Antibody:

IFNL2 / IL28A Mouse anti-Human Monoclonal (C9) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$309; 200 µl/$351; 500 µl/$492; 1 ml/$563; 2 ml/$758; 5 ml/$1,233

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IFNL2 / IL28A Antibody (clone C9, Cy3) LS-C701115

Antibody:

IFNL2 / IL28A Mouse anti-Human Monoclonal (Cy3) (C9) Antibody

Reactivity:

Human

Applications:

WB

Format:

Cy3 Conjugated

Price:

100 µl/$407; 200 µl/$492; 500 µl/$853; 1 ml/$1,013; 2 ml/$1,315; 5 ml/$2,465

• Unconjugated
• Cy3

• Unconjugated
• Cy3

Select

IFNL2 / IL28A Antibody LS-C664021

Antibody:

IFNL2 / IL28A Mouse anti-Human Monoclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$309; 200 µl/$351; 500 µl/$492; 1 ml/$563; 2 ml/$758; 5 ml/$1,233

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IFNL2 / IL28A Antibody (Cy3) LS-C701120

Antibody:

IFNL2 / IL28A Mouse anti-Human Monoclonal (Cy3) Antibody

Reactivity:

Human

Applications:

WB

Format:

Cy3 Conjugated

Price:

100 µl/$407; 200 µl/$492; 500 µl/$853; 1 ml/$1,013; 2 ml/$1,315; 5 ml/$2,465

• Unconjugated
• Cy3

• Unconjugated
• Cy3

Select

IFNL2 / IL28A Antibody LS-C664022

Antibody:

IFNL2 / IL28A Mouse anti-Human Monoclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$309; 200 µl/$351; 500 µl/$492; 1 ml/$563; 2 ml/$758; 5 ml/$1,233

Select

IFNL2 / IL28A Antibody (Cy3) LS-C701119

Antibody:

IFNL2 / IL28A Mouse anti-Human Monoclonal (Cy3) Antibody

Reactivity:

Human

Applications:

WB

Format:

Cy3 Conjugated

Price:

100 µl/$407; 200 µl/$492; 500 µl/$853; 1 ml/$1,013; 2 ml/$1,315; 5 ml/$2,465

• Unconjugated
• Cy3

• Unconjugated
• Cy3

Select

IFNL2 / IL28A Antibody LS-C314037

Antibody:

IFNL2 / IL28A Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

50 µl/$321; 100 µl/$403

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IFNL2 / IL28A Antibody (aa26-200) LS-C314815

Antibody:

IFNL2 / IL28A Rabbit anti-Human Polyclonal (aa26-200) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$303; 200 µl/$343; 500 µl/$476; 1 ml/$543; 2 ml/$715; 5 ml/$1,182

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IFNL2 / IL28A Antibody (aa61-92) LS-C97857

Antibody:

IFNL2 / IL28A Rabbit anti-Human Polyclonal (aa61-92) Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Unconjugated

Price:

400 µl/$393

Select

IFNL2 / IL28A Antibody (Internal) LS-C353673

Antibody:

IFNL2 / IL28A Rabbit anti-Human Polyclonal (Internal) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

30 µl/$255; 50 µl/$271; 100 µl/$299; 200 µl/$351

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