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IFNAR1 / IFNAR
interferon (alpha, beta and omega) receptor 1
Associates with IFNAR2 to form the type I interferon receptor. Receptor for interferons alpha and beta. Binding to type I IFNs triggers tyrosine phosphorylation of a number of proteins including JAKs, TYK2, STAT proteins and IFNR alpha- and beta-subunits themselves. Can also transduce IFNB signals without the help of IFNAR2, and not activating the Jak-STAT pathway.
| Gene Name: | interferon (alpha, beta and omega) receptor 1 |
| Family/Subfamily: | Interferon Receptor , not assigned-Interferon Receptor |
| Synonyms: | IFNAR1, Alpha-type antiviral protein, Beta-type antiviral protein, CRF2-1, IFN-alpha/beta receptor 1, IFN-alpha-REC, IFN-R-1, IFNAR, IFNBR, IFRC, Interferon-beta receptor 1, Interferon-alpha receptor, Type I interferon receptor 1 |
| Target Sequences: | NM_000629 NP_000620.2 P17181 |
Publications (1)
1
Interferon-ß sensitizes human glioblastoma cells to the cyclin-dependent kinase inhibitor, TG02. Birthe Lohmann, Emilie Le Rhun, Manuela Silginer, Mirka Epskamp, Michael Weller. Oncology letters. 2020 Apr;19:2649-2656. [Full Text Article]
[PubMed:32218815]
[PMC:PMC7068396]
☰ Filters
Products
Proteins
(17)
Type
Over-Expression Lysate
(2)
Recombinant
(15)
Target
IFNAR1 / IFNAR
(17)
Publications
No
(17)
Tag
6His, C-terminus
(2)
Fc
(1)
GST
(1)
GST, N-terminus
(1)
His
(4)
His, N-terminus
(2)
His,C-terminus
(2)
Myc-DDK (Flag)
(2)
Species
Human
(10)
Monkey-Rhesus
(1)
Mouse
(4)
Rat
(1)
Source
293T Cells
(1)
E. coli
(5)
HEK 293 Cells
(2)
Human
(2)
Human Cells
(3)
Mammalian Cells
(2)
Wheat Germ Extract
(2)
Purification
Purified
(5)
Low Endotoxin Level
Low endotoxin level
(6)
E. coli
His
31.9 kDa
10 µg/$298; 50 µg/$547; 100 µg/$875; 200 µg/$1,073; 1 mg/$2,252; 500 µg/$1,766; 5 mg/$3,823; 2 mg/$2,443
E. coli
His
28.3 kDa
10 µg/$295; 50 µg/$532; 100 µg/$850; 200 µg/$1,049; 1 mg/$2,215; 500 µg/$1,733; 5 mg/$3,711; 2 mg/$2,407
Human
None
20.7kDa
50 µg/$692; 10 µg/$321; 200 µg/$1,284; 100 µg/$1,082; 1 mg/$2,544; 500 µg/$2,042; 5 mg/$4,831; 2 mg/$2,736
E. coli
His
24.5 kDa
10 µg/$297; 50 µg/$542; 100 µg/$865; 200 µg/$1,065; 1 mg/$2,239; 500 µg/$1,755; 5 mg/$3,781; 2 mg/$2,430
Human
None
19.8kDa
50 µg/$632; 10 µg/$311; 200 µg/$1,200; 100 µg/$1,008; 1 mg/$2,430; 500 µg/$1,934; 5 mg/$4,411; 2 mg/$2,623
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
Wheat Germ Extract
GST
89.9 kDa
2 µg/$439
HEK 293 Cells
Myc-DDK (Flag)
63.53 kDa
100 µg/$494
Human Cells
His
Less than 1.0 EU/µg protein (determined by LAL method).
48.6 kDa
100 µg/$843
Human Cells
Fc
Less than 1.0 EU/µg protein (determined by LAL method).
74 kDa
100 µg/$843
293T Cells
Myc-DDK (Flag)
63.53 kDa
20 µg/$150
E. coli
His, N-terminus
20 kDa
20 µg/$251; 100 µg/$281
E. coli
His, N-terminus
29.36 kDa
20 µg/$270; 100 µg/$390
HEK 293 Cells
His,C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
47 kDa
100 µg/$721
Mammalian Cells
His,C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
48.4 kDa
10 µg/$288; 50 µg/$436
Mammalian Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
48.2 kDa
10 µg/$269; 50 µg/$368
Human Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
48.18kD
10 µg/$269; 50 µg/$372; 500 µg/$1,585; 1 mg/$2,157
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product results
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