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Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.
Gene Name: | interferon, gamma |
Family/Subfamily: | Interferon , not assigned-Interferon |
Synonyms: | IFNG, IFG, Immune interferon, IFI, Interferon gamma, IFN-gamma, Interferon, gamma, IFNY |
Target Sequences: | NM_000619 NP_000610.2 P01579 |
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