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Location
Corporate Headquarters
Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
United States
Telephone Numbers
Customer Service: (800) 227-6666 / (650) 697-3600
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Additional Contact Details
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IDS / Iduronate 2 Sulfatase
iduronate 2-sulfatase
Iduronate-2-sulfatase is required for the lysosomal degradation of heparan sulfate and dermatan sulfate. Mutations in this X-chromosome gene that result in enzymatic deficiency lead to the sex-linked Mucopolysaccharidosis Type II, also known as Hunter Syndrome. Iduronate-2-sulfatase has a strong sequence homology with human arylsulfatases A, B, and C, and human glucosamine-6-sulfatase. A splice variant of this gene has been described.
| Gene Name: | iduronate 2-sulfatase |
| Synonyms: | IDS, SIDS, Iduronate 2-sulfatase, MPS2 |
| Target Sequences: | NM_000202 NP_000193.1 P22304 |
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