ID3

inhibitor of DNA binding 3, dominant negative helix-loop-helix protein

Transcriptional regulator (lacking a basic DNA binding domain) which negatively regulates the basic helix-loop-helix (bHLH) transcription factors by forming heterodimers and inhibiting their DNA binding and transcriptional activity. Implicated in regulating a variety of cellular processes, including cellular growth, senescence, differentiation, apoptosis, angiogenesis, and neoplastic transformation. Involved in myogenesis by inhibiting skeletal muscle and cardiac myocyte differentiation and promoting muscle precursor cells proliferation. Inhibits the binding of E2A-containing protein complexes to muscle creatine kinase E-box enhancer. Regulates the circadian clock by repressing the transcriptional activator activity of the CLOCK-ARNTL/BMAL1 heterodimer.

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Products

Proteins (5)

Type

Over-Expression Lysate (2)

Recombinant (3)

Target

ID3 (5)

Publications

No (5)

Tag

GST (1)

GST, N-terminus (1)

Myc-DDK (Flag) (3)

Species

Human (4)

Source

293T Cells (1)

HEK 293 Cells (2)

Wheat Germ Extract (2)

Purification

Purified (1)

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Human ID3 Protein (Recombinant GST, N-terminus) (aa1-83) - LS-G58931

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human ID3 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G65450

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

12.8 kDa

Price:

20 µg/$1,107

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Human ID3 Protein (Recombinant GST) (Full Length) - LS-G28963

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

38.72 kDa

Price:

10 µg/$479; 25 µg/$670

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Human ID3 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G75590

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

12.8 kDa

Price:

20 µg/$150

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ID3 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G118147

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

12.8 kDa

Price:

100 µg/$494

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