Human IgG2 Fc

The fragment crystallizable region (Fc region) is the tail region of an antibody that interacts with cell surface receptors called Fc receptors and some proteins of the complement system. This property allows antibodies to activate the immune system. In IgG, IgA and IgD antibody isotypes, the Fc region is composed of two identical protein fragments, derived from the second and third constant domains of the antibody's two heavy chains; IgM and IgE Fc regions contain three heavy chain constant domains (CH domains 2–4) in each polypeptide chain. The Fc regions of IgGs bear a highly conserved N-glycosylation site. Glycosylation of the Fc fragment is essential for Fc receptor-mediated activity. The N-glycans attached to this site are predominantly core-fucosylated diantennary structures of the complex type. In addition, small amounts of these N-glycans also bear bisecting GlcNAc and a-2,6 linked sialic acid residues.

Human IgG2 Fc Target Details

☰ Filters

Products

Proteins (3)

Type

Recombinant (3)

Target

Human IgG2 Fc (3)

Publications

No (3)

Species

Human (3)

Source

Human Cells (1)

Mammalian Cells (2)

Purification

Purified (1)

Low Endotoxin Level

Low endotoxin level (3)

Select

Human IgG2 Fc Protein (Recombinant) (Val104-Lys326) - LS-G138585

Source:

Mammalian Cells

Tag:

None

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

25.1 kDa

Price:

10 µg/$233; 50 µg/$277

Select

Human IgG2 Fc Protein (Recombinant) (Glu99-Lys326) - LS-G138584

Source:

Mammalian Cells

Tag:

None

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

25.7 kDa

Price:

10 µg/$233; 50 µg/$277

Select

Human IgG2 Fc Protein (Recombinant) (Glu99-Lys327) - LS-G97571

Source:

Human Cells

Tag:

None

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

25 kDa

Price:

100 µg/$418; 1 mg/$1,400

Viewing 1-3 of 3 product results

(0) Selected Add Selected To Cart Compare Selected Email Selected Clear Selected Top Of Search

---

Filtered By:

Products: Proteins

Clear Filters

If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.