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Human Immunoglobulin G1 (IgG1) is the most abundant subclass of Immunoglobulin G, the most common antibody circulating in the blood. IgG helps protect against infection by binding to various pathogens as part of the secondary immune response. IgG1 has a molecular mass of 146 kD, a mean adult serum level of 6.98 g/l, and a half life of around 21 days. Deficiencies in IgG1 can result in lower total levels of immunoglobulin (hypogammaglobulinemia) and are associated with a propensity for recurrent infection (PMID 25368619).
Target Name: | Human IgG1 |
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