Human IgE

Immunoglobulin E (IgE) is a kind of antibody (or immunoglobulin (Ig) "isotype") that has only been found in mammals. Monomers of IgE consist of two heavy chains (epsilon chain) and two light chains, with the epsilon chain containing 4 Ig-like constant domains. IgE's main function is immunity to parasites such as helminths like Schistosoma mansoni, Trichinella spiralis, and Fasciola hepatica. IgE is utilized during immune defense against certain protozoan parasites such as Plasmodium falciparum. IgE also has an essential role in type I hypersensitivity, which manifests various allergic diseases, such as allergic asthma, most types of sinusitis, allergic rhinitis, food allergies, and specific types of chronic urticaria and atopic dermatitis. IgE also plays a pivotal role in responses to allergens, such as: anaphylactic drugs, bee stings, and antigen preparations used in desensitization immunotherapy. Although IgE is typically the least abundant isotype—blood serum IgE levels in a normal ("non-atopic") individual are only 0.05% of the Ig concentration, compared to 75% for the IgGs at 10 mg/ml, which are the isotypes responsible for most of the classical adaptive immune response—it is capable of triggering the most powerful inflammatory reactions.

Human IgE Target Details

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Products

ELISA Kits (7)

Type

Sandwich (6)

Sandwich CLIA (1)

Target

Human IgE (7)

Reactivity

Human (7)

Format

12 x 8-Well Microstrips (1)

96-Well Microplate (1)

96-Well Strip Plate (5)

Publications

No (7)

Sample Type

Ascites (1)

Cell Culture Supernatants (1)

Cell Lysates (1)

Cell Supernatant (1)

Hybridoma Cell Supernatants (1)

Plasma (7)

Serum (6)

Tissue Homogenates (1)

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Human IgE (Sandwich ELISA) ELISA Kit - LS-F10549

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

1.56 - 100 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$344

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Human IgE (Sandwich ELISA) ELISA Kit - LS-F5244

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

1.56 - 100 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$764

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Human IgE (Sandwich ELISA) ELISA Kit - LS-F10433

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

1 - 500 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Ascites, Hybridoma Cell Supernatants, Plasma

Price:

1 Plate/$741

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Human IgE (Sandwich ELISA) ELISA Kit - LS-F10004

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

62.5 - 4000 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$675

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Human IgE (CLIA) ELISA Kit - LS-F30249

Type:

Sandwich CLIA

Format:

12 x 8-Well Microstrips

Reactivity:

Human

Range:

0.625 - 40 ng/ml

Detection:

Chemiluminescent

Sample Types:

Plasma, Serum

Price:

1 Plate/$656

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Human IgE (Sandwich ELISA) ELISA Kit - LS-F74943

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

3.13 - 200 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Supernatant, Plasma, Serum

Price:

1 Plate/$598

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Human IgE (Sandwich ELISA) ELISA Kit - LS-F27012

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

50 - 1000 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$805

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