Human IgE

Immunoglobulin E (IgE) is a kind of antibody (or immunoglobulin (Ig) "isotype") that has only been found in mammals. Monomers of IgE consist of two heavy chains (epsilon chain) and two light chains, with the epsilon chain containing 4 Ig-like constant domains. IgE's main function is immunity to parasites such as helminths like Schistosoma mansoni, Trichinella spiralis, and Fasciola hepatica. IgE is utilized during immune defense against certain protozoan parasites such as Plasmodium falciparum. IgE also has an essential role in type I hypersensitivity, which manifests various allergic diseases, such as allergic asthma, most types of sinusitis, allergic rhinitis, food allergies, and specific types of chronic urticaria and atopic dermatitis. IgE also plays a pivotal role in responses to allergens, such as: anaphylactic drugs, bee stings, and antigen preparations used in desensitization immunotherapy. Although IgE is typically the least abundant isotype—blood serum IgE levels in a normal ("non-atopic") individual are only 0.05% of the Ig concentration, compared to 75% for the IgGs at 10 mg/ml, which are the isotypes responsible for most of the classical adaptive immune response—it is capable of triggering the most powerful inflammatory reactions.

Human IgE Target Details

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Products

Antibodies (91)

Type

Secondary (91)

Target

Human IgE (91)

Reactivity

Human (90)

Monkey (4)

Application

IHC (29)

IHC-Fr (3)

IHC-P (4)

WB (36)

Flo (25)

CMIA (1)

Colorimetry (1)

DB (3)

ELISA (80)

ELISPOT (1)

ICC (13)

ID (12)

IF (11)

IP (14)

ISH (1)

Peptide-ELISA (2)

RIA (3)

Turbidimetry (1)

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Host

rabbit (6)

mouse (49)

goat (36)

Isotype

IgE (2)

IgG (23)

IgG1 (19)

IgG1,k (2)

IgG2a (12)

IgG2b (13)

IgG2b,k (1)

Clonality

monoclonal mc (49)

polyclonal pc (42)

Clone

1497CT272.23.66 (1)

1497CT744.79.17 (1)

1A2 (1)

4G7 (2)

4H10 (4)

B2687M (1)

BE5 (5)

F4-#16 (1)

Fc-2001 (1)

M94176 (1)

MH25/1 (1)

MHE-18 (1)

NI 307 (5)

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Format

AP Conjugated (6)

APC Conjugated (4)

Azide-free (1)

Biotin Conjugated (12)

Concentrated (1)

FITC Conjugated (14)

HRP Conjugated (13)

PE Conjugated (7)

TRITC Conjugated (2)

Unconjugated (33)

Epitope

aa246-275 (6)

Publications

No (91)

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Mouse Anti-Human IgE Secondary Antibody (clone MHE-18) LS-C40848

Antibody:

Human IgE Mouse anti-Human Monoclonal (MHE-18) Antibody

Reactivity:

Human

Applications:

ELISA, Flo

Format:

Unconjugated

Price:

100 µg/$283

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Mouse Anti-Human IgE Secondary Antibody (clone BE5) LS-C45962

Antibody:

Human IgE Mouse anti-Human Monoclonal (BE5) Antibody

Reactivity:

Human

Applications:

ELISA, Flo

Format:

Unconjugated

Price:

0.1 mg/$281

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Mouse Anti-Human IgE Secondary Antibody (clone BE5, FITC) LS-C46388

Antibody:

Human IgE Mouse anti-Human Monoclonal (FITC) (BE5) Antibody

Reactivity:

Human

Applications:

ELISA, Flo

Format:

FITC Conjugated

Price:

0.1 mg/$316

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Mouse Anti-Human IgE Secondary Antibody (clone BE5, PE) LS-C46492

Antibody:

Human IgE Mouse anti-Human Monoclonal (PE) (BE5) Antibody

Reactivity:

Human

Applications:

ELISA, Flo

Format:

PE Conjugated

Price:

0.1 mg/$344

• Unconjugated
• FITC
• PE

• Unconjugated
• FITC
• PE

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Goat Anti-Human IgE Secondary Antibody LS-C59147

Antibody:

Human IgE Goat anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

1 mg/$396

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Goat Anti-Human IgE Secondary Antibody (FITC) LS-C123814

Antibody:

Human IgE Goat anti-Human Polyclonal (FITC) Antibody

Reactivity:

Human

Applications:

Flo, ICC, IF, IHC

Format:

FITC Conjugated

Price:

1 mg/$558

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Goat Anti-Human IgE Secondary Antibody LS-C316443

Antibody:

Human IgE Goat anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, Flo, ID, IHC, IP, WB

Format:

Unconjugated

Price:

2 mg/$457

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Goat Anti-Human IgE Secondary Antibody (HRP) LS-C315482

Antibody:

Human IgE Goat anti-Human Polyclonal (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, ID, IHC, IP, WB

Format:

HRP Conjugated

Price:

1 mg/$387

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Goat Anti-Human IgE Secondary Antibody (Biotin) LS-C315481

Antibody:

Human IgE Goat anti-Human Polyclonal (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, ID, IHC, IP, WB

Format:

Biotin Conjugated

Price:

1 mg/$375

Select

Goat Anti-Human IgE Secondary Antibody (FITC) LS-C315483

Antibody:

Human IgE Goat anti-Human Polyclonal (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, ID, IF, IHC, IP, WB

Format:

FITC Conjugated

Price:

1 mg/$364

Select

Goat Anti-Human IgE Secondary Antibody (AP) LS-C315479

Antibody:

Human IgE Goat anti-Human Polyclonal (AP) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, ID, IHC, IP, WB

Format:

AP Conjugated

Price:

1 mg/$421

Select

Goat Anti-Human IgE Secondary Antibody (TRITC) LS-C315484

Antibody:

Human IgE Goat anti-Human Polyclonal (TRITC) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, ID, IF, IHC, IP, WB

Format:

TRITC Conjugated

Price:

1 mg/$364

• Unconjugated
• HRP
• Biotin
• FITC
• AP
• TRITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC
  • AP
  • TRITC

Select

Mouse Anti-Human IgE Secondary Antibody (clone MH25/1, Concentrated) LS-C153044

Antibody:

Human IgE Mouse anti-Human Monoclonal (Concentrated) (MH25/1) Antibody

Reactivity:

Human

Applications:

IHC, IHC-Fr, IHC-P

Format:

Unconjugated, Concentrated

Price:

1 ml/$495

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Mouse Anti-Human IgE Secondary Antibody LS-C68463

Antibody:

Human IgE Mouse anti-Human Monoclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, IHC-Fr, IHC-P, RIA

Format:

Unconjugated

Price:

1 ml/$883

Select

Mouse Anti-Human IgE Secondary Antibody (clone 1A2, HRP) LS-C57677

Antibody:

Human IgE Mouse anti-Human Monoclonal (HRP) (1A2) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

HRP Conjugated

Price:

0.5 mg/$846

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Goat Anti-Human IgE Secondary Antibody LS-C129939

Antibody:

Human IgE Goat anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA

Format:

Unconjugated

Price:

2 mg/$672

Select

Mouse Anti-Human IgE Secondary Antibody (HRP) LS-C68493

Antibody:

Human IgE Mouse anti-Human Monoclonal (HRP) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

HRP Conjugated

Price:

100 µg/$548; 500 µg/$1,201

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Rabbit Anti-Human IgE Secondary Antibody (Azide-free, HRP) LS-C259934

Antibody:

Human IgE Rabbit anti-Human Polyclonal (aa246-275) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

Select

Goat Anti-Human IgE Secondary Antibody (HRP) LS-C315495

Antibody:

Human IgE Goat anti-Human Polyclonal (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, ID, IHC, IP, WB

Format:

HRP Conjugated

Price:

1 mg/$482

Select

Goat Anti-Human IgE Secondary Antibody (TRITC) LS-C315496

Antibody:

Human IgE Goat anti-Human Polyclonal (TRITC) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, ID, IF, IHC, IP, WB

Format:

TRITC Conjugated

Price:

1 mg/$459

• HRP
• TRITC

• HRP
• TRITC

Select

Mouse Anti-Human IgE Secondary Antibody (clone 4G7) LS-C45963

Antibody:

Human IgE Mouse anti-Human Monoclonal (4G7) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

Unconjugated

Price:

0.1 mg/$281

Select

Mouse Anti-Human IgE Secondary Antibody LS-C68481

Antibody:

Human IgE Mouse anti-Human Monoclonal Antibody

Reactivity:

Human

Applications:

ELISA

Format:

Unconjugated

Price:

1 mg/$577

Select

Mouse Anti-Human IgE Secondary Antibody (HRP) LS-C68491

Antibody:

Human IgE Mouse anti-Human Monoclonal (HRP) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

HRP Conjugated

Price:

100 µg/$430; 500 µg/$771

Select

Goat Anti-Human IgE Secondary Antibody (FITC) LS-C129933

Antibody:

Human IgE Goat anti-Human Polyclonal (FITC) Antibody

Reactivity:

Human, Monkey

Applications:

Flo

Format:

FITC Conjugated

Price:

1 mg/$611

Select

Mouse Anti-Human IgE Secondary Antibody (clone NI 307, FITC) LS-C346793

Antibody:

Human IgE Mouse anti-Human Monoclonal (FITC) (NI 307) Antibody

Reactivity:

Human

Applications:

ELISA, ICC, IF, IHC, IHC-Fr

Format:

FITC Conjugated

Price:

0.2 mg/$598

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