Human IgA

Immunoglobulin A (IgA, also referred to as sIgA) is an antibody that plays a critical role in mucosal immunity. More IgA is produced in mucosal linings than all other types of antibody combined; between three and five grams are secreted into the intestinal lumen each day. This accumulates up to 15% of the total immunoglobulin produced in the entire body. IgA has two subclasses (IgA1 and IgA2) and can exist in a dimeric form called secretory IgA (sIgA). In its secretory form, IgA is the main immunoglobulin found in mucous secretions, including tears, saliva, sweat, colostrum and secretions from the genitourinary tract, gastrointestinal tract, prostate and respiratory epithelium. It is also found in small amounts in blood. The secretory component of sIgA protects the immunoglobulin from being degraded by proteolytic enzymes, thus sIgA can survive in the harsh gastrointestinal tract environment and provide protection against microbes that multiply in body secretions. sIgA can also inhibit inflammatory effects of other immunoglobulins. IgA is a poor activator of the complement system, and opsonises only weakly. Its heavy chains are of the type alpha.

Human IgA Target Details

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Products

ELISA Kits (6)

Type

Sandwich (5)

Sandwich CLIA (1)

Target

Human IgA (6)

Reactivity

Human (6)

Format

12 x 8-Well Microstrips (1)

96-Well Microplate (1)

96-Well Strip Plate (4)

Publications

No (6)

Sample Type

Cell Supernatant (1)

Plasma (6)

Saliva (1)

Serum (6)

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Human IgA (Sandwich ELISA) ELISA Kit - LS-F5591

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

1.56 - 100 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Saliva, Serum

Price:

1 Plate/$685

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Human IgA (Sandwich ELISA) ELISA Kit - LS-F10060

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

0.24 - 1000 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$563

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Human IgA (Sandwich ELISA) ELISA Kit - LS-F74947

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

6.25 - 400 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Supernatant, Plasma, Serum

Price:

1 Plate/$598

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Human IgA (Sandwich ELISA) ELISA Kit - LS-F28770

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

5 - 100 U/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$805

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Human IgA (CLIA) ELISA Kit - LS-F29882

Type:

Sandwich CLIA

Format:

12 x 8-Well Microstrips

Reactivity:

Human

Range:

3.125 - 200 ng/ml

Detection:

Chemiluminescent

Sample Types:

Plasma, Serum

Price:

1 Plate/$656

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Human IgA (Sandwich ELISA) ELISA Kit - LS-F10551

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.312 - 20 µg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$344

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