Orders Processing,
Shipping & Receiving,
Warehouse
2 Shaker Rd Suites
B001/B101
Shirley, MA 01464
Production Lab
Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036
Serine protease that cleaves beta-casein/CSN2 as well as several extracellular matrix (ECM) proteoglycans such as decorin/DCN, biglycan/BGN and fibronectin/FN1. Inhibits signaling mediated by TGF-beta family proteins possibly indirectly by degradation of these ECM proteoglycans By similarity. May act as a tumor suppressor. Negatively regulates, in vitro, trophoblast invasion during placental development and may be involved in the development of the placenta in vivo. May also have a role in ovarian development, granulosa cell differentiation and luteinization.
Gene Name: | HtrA serine peptidase 3 |
Family/Subfamily: | Protease , Serine S1C |
Synonyms: | HTRA3, HtrA serine peptidase 3, Serine protease HTRA3, Tasp, Probable serine protease HTRA3, PRSP |
Target Sequences: | NM_053044 NP_444272.1 P83110 |
If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.