HTR2B / 5-HT2B Receptor

5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled

G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various ergot alkaloid derivatives and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Signaling activates a phosphatidylinositol-calcium second messenger system that modulates the activity of phosphatidylinositol 3-kinase and down-stream signaling cascades and promotes the release of Ca2+ ions from intracellular stores. Plays a role in the regulation of dopamine and 5-hydroxytryptamine release, 5-hydroxytryptamine uptake and in the regulation of extracellular dopamine and 5-hydroxytryptamine levels, and thereby affects neural activity. May play a role in the perception of pain. Plays a role in the regulation of behavior, including impulsive behavior. Required for normal proliferation of embryonic cardiac myocytes and normal heart development. Protects cardiomyocytes against apoptosis. Plays a role in the adaptation of pulmonary arteries to chronic hypoxia. Plays a role in vasoconstriction. Required for normal osteoblast function and proliferation, and for maintaining normal bone density. Required for normal proliferation of the interstitial cells of Cajal in the intestine.

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Products

Antibodies (29)

Proteins (4)

Type

Primary (29)

Recombinant (4)

Target

HTR2B / 5-HT2B Receptor (33)

Reactivity

Human (28)

Mouse (6)

Rat (5)

Bovine (3)

Chimpanzee (2)

Dog (3)

Guinea pig (3)

Monkey (1)

Orangutan (2)

Pig (2)

Rabbit (1)

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Application

IHC (14)

IHC-P (6)

WB (24)

ELISA (8)

IF (7)

IP (1)

Peptide-ELISA (5)

Host

rabbit (26)

mouse (1)

rabbit-new zealand white (2)

Product Group

GPCR Database Antibodies (2)

IHCPlus (2)

PathPlus Neuro (2)

Isotype

IgG (15)

IgG2a,k (1)

Clonality

monoclonal mc (1)

polyclonal pc (28)

Clone

4A4 (1)

Format

Biotin Conjugated (1)

FITC Conjugated (1)

HRP Conjugated (1)

Unconjugated (26)

Epitope

aa35-84 (4)

N-Terminus (2)

30-110 aa, N-terminal (1)

Extracellular Domain (1)

aa15-64 (1)

aa233-282 (1)

aa261-310 (1)

aa390-440 (1)

aa440-481 (1)

aa446-478 (1)

aa6-55 (1)

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Publications

No (32)

Yes (1)

Tag

6His-SUMO, N-terminus (1)

GST (1)

GST, N-terminus (2)

Species

Human (4)

Source

E. coli (1)

Wheat Germ Extract (3)

Purification

Purified (2)

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IHC-plus™ HTR2B / 5-HT2B Receptor Antibody LS-B13590

(5.0) Rating

(1) Publication(s)

Antibody:

HTR2B / 5-HT2B Receptor Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$460

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PathPlus™ HTR2B / 5-HT2B Receptor Antibody (Extracellular Domain) LS-A1111

Neuroscience

Fast Shipping

(5.0) Rating

Antibody:

HTR2B / 5-HT2B Receptor Rabbit anti-Human Polyclonal (Extracellular Domain) Antibody

Reactivity:

Human, Monkey

Applications:

IHC, IHC-P

Format:

Unconjugated

Price:

50 µg/$440

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PathPlus™ HTR2B / 5-HT2B Receptor Antibody (N-Terminus) LS-A1187

Neuroscience

Fast Shipping

(5.0) Rating

Antibody:

HTR2B / 5-HT2B Receptor Rabbit anti-Human Polyclonal (N-Terminus) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P

Format:

Unconjugated

Price:

50 µg/$440

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HTR2B / 5-HT2B Receptor Antibody LS-C334205

Antibody:

HTR2B / 5-HT2B Receptor Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, WB

Format:

Unconjugated

Price:

20 µl/$275; 100 µl/$389

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IHC-plus™ HTR2B / 5-HT2B Receptor Antibody (aa15-64) LS-B9273

(4.0) Rating

Antibody:

HTR2B / 5-HT2B Receptor Rabbit anti-Human Polyclonal (aa15-64) Antibody

Reactivity:

Human

Applications:

IF, IHC, IHC-P, Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$440

Select

HTR2B / 5-HT2B Receptor Antibody (aa261-310) LS-C119368

Antibody:

HTR2B / 5-HT2B Receptor Rabbit anti-Human Polyclonal (aa261-310) Antibody

Reactivity:

Human

Applications:

IF, IHC, IHC-P, Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

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HTR2B / 5-HT2B Receptor Antibody (aa35-84) LS-C109575

Antibody:

HTR2B / 5-HT2B Receptor Rabbit anti-Human Polyclonal (aa35-84) Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

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HTR2B / 5-HT2B Receptor Antibody (aa35-84, FITC) LS-C426037

Antibody:

HTR2B / 5-HT2B Receptor Rabbit anti-Human Polyclonal (aa35-84) (FITC) Antibody

Reactivity:

Bovine, Human

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• FITC

• Unconjugated
• FITC

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HTR2B / 5-HT2B Receptor Antibody (aa446-478) LS-C407814

Antibody:

HTR2B / 5-HT2B Receptor Rabbit anti-Human Polyclonal (aa446-478) Antibody

Reactivity:

Rabbit, Dog, Guinea pig, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

10 µg/$318; 100 µg/$470

Select

HTR2B / 5-HT2B Receptor Antibody LS-C746820

Antibody:

HTR2B / 5-HT2B Receptor Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Unconjugated

Price:

20 µl/$275; 100 µl/$389

Select

HTR2B / 5-HT2B Receptor Antibody LS-C823355

Antibody:

HTR2B / 5-HT2B Receptor Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, WB

Format:

Unconjugated

Price:

100 µg/$357

Select

HTR2B / 5-HT2B Receptor Antibody LS-C809329

Antibody:

HTR2B / 5-HT2B Receptor Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IF, IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

Select

HTR2B / 5-HT2B Receptor Antibody LS-C675873

Antibody:

HTR2B / 5-HT2B Receptor Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P

Format:

Unconjugated

Price:

50 µl/$294; 100 µl/$360

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HTR2B / 5-HT2B Receptor Antibody (30-110 aa, N-terminal) LS-C386169

Antibody:

HTR2B / 5-HT2B Receptor Rabbit anti-Human Polyclonal (30-110 aa, N-terminal) Antibody

Reactivity:

Human

Applications:

ELISA, IF, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

Select

HTR2B / 5-HT2B Receptor Antibody LS-C826781

Antibody:

HTR2B / 5-HT2B Receptor Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, WB

Format:

Unconjugated

Price:

100 µg/$357

Select

HTR2B / 5-HT2B Receptor Antibody LS-C403799

Antibody:

HTR2B / 5-HT2B Receptor Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

Select

HTR2B / 5-HT2B Receptor Antibody (aa233-282) LS-C200061

Antibody:

HTR2B / 5-HT2B Receptor Rabbit anti-Human Polyclonal (aa233-282) Antibody

Reactivity:

Human

Applications:

IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

Select

HTR2B / 5-HT2B Receptor Antibody (aa390-440) LS-C829726

Antibody:

HTR2B / 5-HT2B Receptor Rabbit-New Zealand White anti-Mouse Polyclonal (aa390-440) Antibody

Reactivity:

Mouse

Applications:

IHC, WB

Format:

Unconjugated

Price:

100 µl/$393

Select

HTR2B / 5-HT2B Receptor Antibody LS-C767375

Antibody:

HTR2B / 5-HT2B Receptor Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

Select

HTR2B / 5-HT2B Receptor Antibody LS-C400532

Antibody:

HTR2B / 5-HT2B Receptor Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

Select

HTR2B / 5-HT2B Receptor Antibody (clone 4A4) LS-C197473

Antibody:

HTR2B / 5-HT2B Receptor Mouse anti-Human Monoclonal (4A4) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$423

Select

HTR2B / 5-HT2B Receptor Antibody (aa440-481) LS-C829546

Antibody:

HTR2B / 5-HT2B Receptor Rabbit-New Zealand White anti-Human Polyclonal (aa440-481) Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

100 µl/$393

Select

HTR2B / 5-HT2B Receptor Antibody (aa6-55) LS-C292077

Antibody:

HTR2B / 5-HT2B Receptor Rabbit anti-Human Polyclonal (aa6-55) Antibody

Reactivity:

Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

Select

HTR2B / 5-HT2B Receptor Antibody (N-Terminus) LS-C352333

Antibody:

HTR2B / 5-HT2B Receptor Rabbit anti-Human Polyclonal (N-Terminus) Antibody

Reactivity:

Human

Applications:

IP, WB

Format:

Unconjugated

Price:

100 µl/$299

Select

HTR2B / 5-HT2B Receptor Antibody LS-C95998

Antibody:

HTR2B / 5-HT2B Receptor Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA

Format:

Unconjugated

Price:

100 µg/$407

Viewing 1-25 of 33 product results

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